Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives

Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress

(2018) Rongshuang Yuan et al.   BIOMEDICINE & PHARMACOTHERAPY

An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis

(2018) Kandhasamy Sowndhararajan et al.   BIOMEDICINE & PHARMACOTHERAPY

Schisandrin A prevents oxidative stress-induced DNA damage and apoptosis by attenuating ROS generation in C2C12 cells

(2018) Yung Hyun Choi   BIOMEDICINE & PHARMACOTHERAPY

Gomisin G Inhibits the Growth of Triple-Negative Breast Cancer Cells by Suppressing AKT Phosphorylation and Decreasing Cyclin D1

(2018) Sony Maharjan et al.   Biomolecules & Therapeutics

A review of polysaccharides from Schisandra chinensis and Schisandra sphenanthera : Properties, functions and applications

(2018) Zijian Li et al.   CARBOHYDRATE POLYMERS

Characteristics and Antioxidant Activity of Lignans in Schisandra chinensis and Schisandra sphenanthera from Different Locations

(2018) Xinting Wang et al.   CHEMISTRY & BIODIVERSITY

Gomisin A modulates aging progress via mitochondrial biogenesis in human diploid fibroblast cells

(2018) Jeong-Seok Kim et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases

(2018) Minyu Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biochemical deficits and cognitive decline in brain aging: Intervention by dietary supplements

(2018) Jit Poddar et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Muscle-protective effects of Schisandrae Fructus extracts in old mice after chronic forced exercise

(2018) Ki-Young Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of Lignans from Schisandra chinensis Rattan Stems against Aβ1-42-Induced Memory Impairment in Rats and Neurotoxicity in Primary Neuronal Cells

(2018) Bing-You Yang et al.   MOLECULES

New lignan from the rattan stems of Schisandra chinensis

(2018) Bing-You Yang et al.   NATURAL PRODUCT RESEARCH

Protective effects of Schisandrin on high glucose-induced changes of RhoA and eNOS activity in human umbilical vein endothelial cells

(2018) Rong-Jin Zhang et al.   PATHOLOGY RESEARCH AND PRACTICE

Three new nortriterpenoids from the rattan stems of Schisandra chinensis

(2018) Bing-You Yang et al.   Phytochemistry Letters

Deoxyschizandrin, Isolated from Schisandra Berries, Induces Cell Cycle Arrest in Ovarian Cancer Cells and Inhibits the Protumoural Activation of Tumour-Associated Macrophages

(2018) Kijun Lee et al.   Nutrients

Sarcopenia: assessment of disease burden and strategies to improve outcomes

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Metabolomics study of the therapeutic mechanism of Schisandra chinensis lignans on aging rats induced by D-galactose

(2018) Jinghui Sun et al.   Clinical Interventions in Aging

Schisandrin B protects human keratinocyte-derived HaCaT�cells from tert-butyl hydroperoxide-induced oxidative damage through activating the Nrf2 signaling pathway

(2018) Ming Ding et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Deoxyschizandrin Loaded Liposomes on the Suppression Lipid Accumulation in 3T3-L1 Adipocytes

(2018) Xiaona Liu et al.   MOLECULES

Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3

(2018) Xuanxuan Dai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells

(2018) Ji-Ye Kee et al.   Frontiers in Pharmacology

Rapid Classification and Identification of Chemical Components of Schisandra Chinensis by UPLC-Q-TOF/MS Combined with Data Post-Processing

(2017) Shenshen Yang et al.   MOLECULES

Schisandra chinensis berry extract protects against steatosis by inhibiting histone acetylation in oleic acid–treated HepG2 cells and in the livers of diet-induced obese mice

(2017) Min-Yu Chung et al.   NUTRITION RESEARCH

Studies on the accumulation of phenolic acids and flavonoids in different in vitro culture systems of Schisandra chinensis (Turcz.) Baill. using a DAD-HPLC method

(2017) Agnieszka Szopa et al.   Phytochemistry Letters

Schisandrin A inhibits dengue viral replication via upregulating antiviral interferon responses through STAT signaling pathway

(2017) Jung-Sheng Yu et al.   Scientific Reports

Schisandrin B regulates lipid metabolism in subcutaneous adipocytes

(2017) Hiu Yee Kwan et al.   Scientific Reports

Metabolic mechanism of a polysaccharide from Schisandra chinensis to relieve chronic fatigue syndrome

(2016) Aiping Chi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Schisandra polysaccharide increased glucose consumption by up-regulating the expression of GLUT-4

(2016) Dun Jin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Schisandrae fructus enhances myogenic differentiation and inhibits atrophy through protein synthesis in human myotubes

(2016) Cy Hyun Kim et al.   International Journal of Nanomedicine

Enzymatic assays and molecular modeling studies of Schisandra chinensis lignans and phenolics from fruit and leaf extracts

(2016) Andrei Mocan et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Antitussive activity of the Schisandra chinensis fruit polysaccharide (SCFP-1) in guinea pigs models

(2016) Shan Zhong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Schisandra chinensis extract ameliorates nonalcoholic fatty liver via inhibition of endoplasmic reticulum stress

(2016) Min-Kyung Jang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Schisandra polysaccharide inhibits hepatic lipid accumulation by downregulating expression of SREBPs in NAFLD mice

(2016) Chun-Mei Wang et al.   Lipids in Health and Disease

Lignans from Schisandra chinensis ameliorate cognition deficits and attenuate brain oxidative damage induced by D-galactose in rats

(2016) Tingxu Yan et al.   METABOLIC BRAIN DISEASE

A Continuous Procedure Based on Column Chromatography to Purify Anthocyanins from Schisandra chinensis by a Macroporous Resin plus Gel Filtration Chromatography

(2016) Daran Yue et al.   MOLECULES

Oxidative Stress Related Diseases in Newborns

(2016) Yasemin Ozsurekci et al.   Oxidative Medicine and Cellular Longevity

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

(2016) Agnieszka Szopa et al.   PHYTOCHEMISTRY REVIEWS

The importance of applied light quality on the production of lignans and phenolic acids in Schisandra chinensis (Turcz.) Baill. cultures in vitro

(2016) Agnieszka Szopa et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Natural phytochemicals and probiotics as bioactive ingredients for functional foods: Extraction, biochemistry and protected-delivery technologies

(2016) Beatriz Vieira da Silva et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Regulation of AMP-activated protein kinase by natural and synthetic activators

(2016) David Grahame Hardie   Acta Pharmaceutica Sinica B

Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response

(2016) Pou Kuan Leong et al.   PLoS One

Antidiabetic Effect of Polyphenolic Extracts from Selected Edible Plants as α-Amylase, α -Glucosidase and PTP1B Inhibitors, and β Pancreatic Cells Cytoprotective Agents - A Comparative Study

(2015) Małgorzata Zakłos-Szyda et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Schisandrae FructusInhibits IL-1β-Induced Matrix Metalloproteinases and Inflammatory Mediators Production in SW1353 Human Chondrocytes by Suppressing NF-κB and MAPK Activation

(2015) Jin-Woo Jeong et al.   DRUG DEVELOPMENT RESEARCH

Schisanhenol derivatives and their biological evaluation against tobacco mosaic virus (TMV)

(2015) Qing-Yao Wang et al.   FITOTERAPIA

The ability ofSchisandra chinensisfruit to inhibit the growth of foodborne pathogenic bacteria and the viability and heat resistance ofBacillus cereusspores

(2015) Xuezhi Bai et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in mice

(2015) JOO WAN KIM et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Dibenzocyclooctadiene lignans from Schisandra spp. selectively inhibit the growth of the intracellular bacteria Chlamydia pneumoniae and Chlamydia trachomatis

(2015) Elina Hakala et al.   JOURNAL OF ANTIBIOTICS

Highly oxygenated triterpenoids from the roots ofSchisandra chinensisand their anti-inflammatory activities

(2015) Qiu-Yan Song et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Identification and analysis of anthocyanin components in fruit color variation in Schisandra chinensis

(2015) Jingjing Liao et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Schisandra chinensis fruit modulates the gut microbiota composition in association with metabolic markers in obese women: a randomized, double-blind placebo-controlled study

(2015) Mi-young Song et al.   NUTRITION RESEARCH

Induction of reactive oxygen species–mediated apoptosis by purified Schisandrae semen essential oil in human leukemia U937 cells through activation of the caspase cascades and nuclear relocation of mitochondrial apoptogenic factors

(2015) Gyeong Jin Yu et al.   NUTRITION RESEARCH

Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in Mice

(2015) Joo Wan Kim et al.   Oxidative Medicine and Cellular Longevity

Isolation and anti-hepatitis B virus activity of dibenzocyclooctadiene lignans from the fruits of Schisandra chinensi s

(2015) Yongbo Xue et al.   PHYTOCHEMISTRY

Extracts and lignans of Schisandra chinensis fruit alter lipid and glucose metabolism in vivo and in vitro

(2015) Haitao Liu et al.   Journal of Functional Foods

Effects of combined dietary supplementation with fenofibrate and Schisandrae Fructus pulp on lipid and glucose levels and liver function in normal and hypercholesterolemic mice

(2015) Si-Yuan Pan et al.   Drug Design Development and Therapy

Schisandrin B Prevents Doxorubicin Induced Cardiac Dysfunction by Modulation of DNA Damage, Oxidative Stress and Inflammation through Inhibition of MAPK/p53 Signaling

(2015) Rajarajan A. Thandavarayan et al.   PLoS One

The Protecting Effect of Deoxyschisandrin and Schisandrin B on HaCaT Cells against UVB-Induced Damage

(2015) Wei Hou et al.   PLoS One

Antibacterial and antioxidant activities and chemical compositions of volatile oils extracted fromSchisandra chinensisBaill. seeds using simultaneous distillation extraction method, and comparison with Soxhlet and microwave-assisted extraction

(2014) Hui Teng et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Antidiabetic Effect of Schisandrae Chinensis Fructus Involves Inhibition of the Sodium Glucose Cotransporter

(2014) Yue Qu et al.   DRUG DEVELOPMENT RESEARCH

Phytochemical investigation of sesquiterpenes from the fruits of Schisandra chinensis and their cytotoxic activity

(2014) A. Venkanna et al.   FITOTERAPIA

Molecular mechanisms of antiproliferative effects induced by Schisandra-derived dibenzocyclooctadiene lignans (+)-deoxyschisandrin and (−)-gomisin N in human tumour cell lines

(2014) Elisabetta Casarin et al.   FITOTERAPIA

Schisandra polysaccharide evokes immunomodulatory activity through TLR 4-mediated activation of macrophages

(2014) Ting Zhao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antitumor and antiangiogenic activity of Schisandra chinensis polysaccharide in a renal cell carcinoma model

(2014) Hai-Ming Qu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Schisandrae semen essential oil attenuates oxidative stress-induced cell damage in C2C12 murine skeletal muscle cells through Nrf2-mediated upregulation of HO-1

(2014) JI SOOK KANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Omija Fruit Extract Improves Endurance and Energy Metabolism by Upregulating PGC-1α Expression in the Skeletal Muscle of Exercised Rats

(2014) Young-Je Kim et al.   JOURNAL OF MEDICINAL FOOD

Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis

(2014) ZHIYUAN WU et al.   Molecular Medicine Reports

Comparative Studies on Polyphenolic Composition, Antioxidant and Antimicrobial Activities of Schisandra chinensis Leaves and Fruits

(2014) Andrei Mocan et al.   MOLECULES

Schizandra chinensisextracts induce apoptosis in human gastric cancer cells via JNK/p38 MAPK activation and the ROS-mediated/mitochondria-dependent pathway

(2014) Hyun Sul Kim et al.   PHARMACEUTICAL BIOLOGY

Schisandraceae triterpenoids: a review

(2014) Yong-Gang Xia et al.   PHYTOCHEMISTRY REVIEWS

SCP, a polysaccharide from Schisandra chinensis, induces apoptosis in human renal cell carcinoma Caki-1 cells through mitochondrial-dependent pathway via inhibition of ERK activation

(2014) Shi-Jian Liu et al.   TUMOR BIOLOGY

Protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase inhibitory activities of Schisandra chinensis (Turcz.) Baill

(2014) Linlin Fang et al.   Journal of Functional Foods

Nrf2-Mediated HO-1 Induction Contributes to Antioxidant Capacity of a Schisandrae Fructus Ethanol Extract in C2C12 Myoblasts

(2014) Ji Kang et al.   Nutrients

In vitro Cell Migration and Invasion Assays

(2014) Calvin R. Justus et al.   Jove-Journal of Visualized Experiments

Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis (Turcz.) Baill

(2013) Ting Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

Antioxidant and anti-proliferative activities of five compounds from Schisandra chinensis fruit

(2013) Likang Zhang et al.   INDUSTRIAL CROPS AND PRODUCTS

Extraction optimization of polysaccharides of Schisandrae Fructus and evaluation of their analgesic activity

(2013) Chun Ye et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The SLC2 (GLUT) family of membrane transporters

(2013) Mike Mueckler et al.   MOLECULAR ASPECTS OF MEDICINE

Comprehensive chemical analysis of Schisandra chinensis by HPLC–DAD–MS combined with chemometrics

(2013) Haitao Liu et al.   PHYTOMEDICINE

Nortriterpenoids from Schisandra chinensis and their absolute configurational assignments by electronic circular dichroism study

(2013) Yi-Ming Shi et al.   TETRAHEDRON

Analysis of lignans in Schisandra chinensis fruits, leaves, biomasses from in vitro cultures and food supplements

(2013) Radosław J. Ekiert et al.   Journal of Functional Foods

Isolation and physicochemical characterization of polysaccharide fractions isolated from Schisandra chinensis

(2012) Haibin Tong et al.   CHEMISTRY OF NATURAL COMPOUNDS

Anti-obesity effect of Schisandra chinensis in 3T3-L1 cells and high fat diet-induced obese rats

(2012) Hyoung Joon Park et al.   FOOD CHEMISTRY

Content and Color Stability of Anthocyanins Isolated from Schisandra chinensis Fruit

(2012) Chunhui Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Schisandrin B Attenuates Cancer Invasion and Metastasis Via Inhibiting Epithelial-Mesenchymal Transition

(2012) Zhen Liu et al.   PLoS One

Inhibitory effect of Schisandra chinensis leaf polysaccharide against L5178Y lymphoma

(2011) Chunlin Xu et al.   CARBOHYDRATE POLYMERS

Schisandrin B protects against solar irradiation-induced oxidative injury in BJ human fibroblasts

(2011) Po Yee Chiu et al.   FITOTERAPIA

In Vitro and in Vivo Anti-Hyperglycemic Effects of Omija (Schizandra chinensis) Fruit

(2011) Sung-Hoon Jo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The lignan-rich fractions of Fructus Schisandrae improve insulin sensitivity via the PPAR-γ pathways in in vitro and in vivo studies

(2011) Dae Young Kwon et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of GLUT4 expression on insulin resistance in patients with advanced liver cirrhosis

(2011) Wei-feng Shan et al.   Journal of Zhejiang University-SCIENCE B

Nortriterpenoids and Lignans from the Fruit of Schisandra chinensis

(2010) Yong-Bo Xue et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue

(2010) Philip Y. Lam et al.   FITOTERAPIA

Fatty acid synthase inhibitory activity of dibenzocyclooctadiene lignans isolated from Schisandra chinensis

(2010) MinKyun Na et al.   PHYTOTHERAPY RESEARCH

Long-term schisandrin B treatment mitigates age-related impairments in mitochondrial antioxidant status and functional ability in various tissues, and improves the survival of aging C57BL/6J mice

(2009) Kam Ming Ko et al.   BIOFACTORS

Huang-Lian-Jie-Du-Tang Supplemented withSchisandra chinensisBaill. andPolygonatum odoratumDruce Improved Glucose Tolerance by Potentiating Insulinotropic Actions in Islets in 90% Pancreatectomized Diabetic Rats

(2009) Sunmin PARK et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apoptotic effects in hepatic carcinoma

(2009) Hwang   Molecular Medicine Reports

Medicinal Plants and Cancer Chemoprevention

(2008) Avni Desai et al.   CURRENT DRUG METABOLISM

Determination of six lignans in Schisandra chinensis (Turcz.) Baill. Fruits and related Chinese multiherb remedies by HPLC

(2008) Hai Zhang et al.   FOOD CHEMISTRY

Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine

(2008) Alexander Panossian et al.   JOURNAL OF ETHNOPHARMACOLOGY

Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and inhibit associated changes in Ca2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes

(2008) Po Yee Chiu et al.   LIFE SCIENCES

Cellular senescence and organismal aging

(2008) Jessie C. Jeyapalan et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Brain Oxidative Stress as Basic Target of Antioxidant Traditional Oriental Medicines

(2008) Tetsuya Konishi   NEUROCHEMICAL RESEARCH

Isolation and characterization of miscellaneous terpenoids of Schisandra chinensis

(2008) Sheng-Xiong Huang et al.   TETRAHEDRON