Beneficial Effects of Pomegranate on Lipid Metabolism in Metabolic Disorders

Bioactivity and biotechnological production of punicic acid

(2018) Roman Holic et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Ellagic acid mitigates arsenic-trioxide-induced mitochondrial dysfunction and cytotoxicity in SH-SY5Y cells

(2018) Fakiha Firdaus et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells

(2018) Francisco Les et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cholesterol-lowering effects of dietary pomegranate extract and inulin in mice fed an obesogenic diet

(2018) Jieping Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Pomegranate peel polyphenols inhibits inflammation in LPS-induced RAW264.7 macrophages via the suppression of MAPKs activation

(2018) Lin Du et al.   Journal of Functional Foods

Punicic acid: A potential compound of pomegranate seed oil in Type 2 diabetes mellitus management

(2018) Yaser Khajebishak et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Subclinical hypothyroidism, lipid metabolism and cardiovascular disease

(2017) Alessandro P Delitala et al.   European Journal of Internal Medicine

Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and HypertensionNovelty and Significance

(2017) Stefan Engeli et al.   HYPERTENSION

Pomegranate juice and its main polyphenols exhibit direct effects on amine oxidases from human adipose tissue and inhibit lipid metabolism in adipocytes

(2017) Francisco Les et al.   Journal of Functional Foods

Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways

(2017) Animesh Mandal et al.   Nutrients

Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease

(2016) William Herrington et al.   CIRCULATION RESEARCH

Pomegranate peel extract polyphenols induced apoptosis in human hepatoma cells by mitochondrial pathway

(2016) Bingbing Song et al.   FOOD AND CHEMICAL TOXICOLOGY

Ellagic acid confers protection against gentamicin-induced oxidative damage, mitochondrial dysfunction and apoptosis-related nephrotoxicity

(2016) Mohammad Reza Sepand et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Antimicrobial activity of pomegranate peel extracts as affected by cultivar

(2016) Ema C Rosas-Burgos et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Punicalagin attenuates palmitate-induced lipotoxicity in HepG2 cells by activating the Keap1-Nrf2 antioxidant defense system

(2016) Chunhong Yan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

(2016) Dongryeol Ryu et al.   NATURE MEDICINE

Neuroprotective Effects of Pomegranate Peel Extract after Chronic Infusion with Amyloid-β Peptide in Mice

(2016) Maressa Caldeira Morzelle et al.   PLoS One

Comparison of potential preventive effects of pomegranate flower, peel and seed oil on insulin resistance and inflammation in high-fat and high-sucrose diet-induced obesity mice model

(2016) Arij Harzallah et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Effect Of Walnut Leaf, Coriander And Pomegranate On Blood Glucose And Histopathology Of Pancreas Of Alloxan Induced Diabetic Rats

(2016) G Jelodar et al.   African Journal of Traditional Complementary and Alternative Medicines

Pomegranate extract decreases oxidative stress and alleviates mitochondrial impairment by activating AMPK-Nrf2 in hypothalamic paraventricular nucleus of spontaneously hypertensive rats

(2016) Wenyan Sun et al.   Scientific Reports

Chemical fingerprint and quantitative analysis for quality control of polyphenols extracted from pomegranate peel by HPLC

(2015) Jianke Li et al.   FOOD CHEMISTRY

Meat composition, fatty acid profile and oxidative stability of meat from broilers supplemented with pomegranate (Punica granatum L.) by-products

(2015) Sonia Tabasum Ahmed et al.   FOOD CHEMISTRY

Pomegranate peel extract decreases small intestine lipid peroxidation by enhancing activities of major antioxidant enzymes

(2015) Kaïs H Al-Gubory et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Effects of ellagic acid-rich extract of pomegranates peel on regulation of cholesterol metabolism and its molecular mechanism in hamsters

(2015) Run Liu et al.   Food & Function

Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation

(2015) Ke Cao et al.   Scientific Reports

Pomegranate(Punicagranatum)juice decreases lipid peroxidation, but has no effect on plasma advanced glycated end-products in adults with type 2 diabetes: a randomized double-blind clinical trial

(2015) Golbon Sohrab et al.   Food & Nutrition Research

Mitochondrial Dysfunction in Obesity-Associated Nonalcoholic Fatty Liver Disease: The Protective Effects of Pomegranate with Its Active Component Punicalagin

(2014) Xuan Zou et al.   ANTIOXIDANTS & REDOX SIGNALING

Pomegranate juice consumption increases GSH levels and reduces lipid and protein oxidation in human blood

(2014) Chrysoula M. Matthaiou et al.   FOOD AND CHEMICAL TOXICOLOGY

Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review

(2014) Imen Belhadj Slimen et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats

(2014) Maha A.E. Ahmed et al.   LIFE SCIENCES

Triterpenes as uncompetitive inhibitors of α-glucosidase from flowers ofPunica granatumL.

(2014) Riham Salah El Dine et al.   NATURAL PRODUCT RESEARCH

Omega-3 Fatty Acids, Hepatic Lipid Metabolism, and Nonalcoholic Fatty Liver Disease

(2013) E. Scorletti et al.   Annual Review of Nutrition

MnSOD in Oxidative Stress Response-Potential Regulation via Mitochondrial Protein Influx

(2013) Demet Candas et al.   ANTIOXIDANTS & REDOX SIGNALING

Ellagic acid improves hepatic steatosis and serum lipid composition through reduction of serum resistin levels and transcriptional activation of hepatic ppara in obese, diabetic KK-Ay mice

(2013) Yukihiro Yoshimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria

(2013) Irina V. Perevoshchikova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

(2013) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of cholesterol and bile acid homeostasis by the cholesterol 7α-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice

(2013) Tiangang Li et al.   HEPATOLOGY

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

Antioxidant and antibacterial potential of pomegranate peel extracts

(2013) Shalini Malviya et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Pomegranate vinegar attenuates adiposity in obese rats through coordinated control of AMPK signaling in the liver and adipose tissue

(2013) Elly Ok et al.   Lipids in Health and Disease

Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review

(2013) Janett Barbaresko et al.   NUTRITION REVIEWS

Hypolipidemic effect of fruit fibers in rats fed with high dietary fat

(2013) O.A. Esmael et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Pharmacologic agents for type 2 diabetes therapy and regulation of adipogenesis

(2013) A. Cignarelli et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

High-Density Lipoprotein Function, Dysfunction, and Reverse Cholesterol Transport

(2012) Edward A. Fisher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

Transcriptional regulation of cholesterol and bile acid metabolism after dietary soyabean meal treatment in Atlantic salmon (Salmo salar L.)

(2012) Trond M. Kortner et al.   BRITISH JOURNAL OF NUTRITION

Recent Advancements in the LC- and GC-Based Analysis of Malondialdehyde (MDA): A Brief Overview

(2012) Martin Giera et al.   CHROMATOGRAPHIA

Characterization and evaluation of major anthocyanins in pomegranate (Punica granatum L.) peel of different cultivars and their development phases

(2012) Xueqing Zhao et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats

(2012) Sunil K. Panchal et al.   EUROPEAN JOURNAL OF NUTRITION

Extraction optimization of oleanolic and ursolic acids from pomegranate (Punica granatum L.) flowers

(2012) Quanjuan Fu et al.   FOOD AND BIOPRODUCTS PROCESSING

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

(2012) Michael H. Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome

(2012) Anneke M.J. van Hees et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Rapid and Comprehensive Evaluation of (Poly)phenolic Compounds in Pomegranate (Punica granatum L.) Juice by UHPLC-MSn

(2012) Pedro Mena et al.   MOLECULES

Obesity: The preventive role of the pomegranate (Punica granatum)

(2012) May Nasser Al-Muammar et al.   NUTRITION

Pomegranate as a Functional Food and Nutraceutical Source

(2012) Suzanne D. Johanningsmeier et al.   Annual Review of Food Science and Technology

Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress

(2011) S. Gómez-Zorita et al.   BRITISH JOURNAL OF NUTRITION

Antioxidant Capacities of Phenolic Compounds and Tocopherols from Tunisian Pomegranate (Punica granatum) Fruits

(2011) Walid Elfalleh et al.   JOURNAL OF FOOD SCIENCE

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pomegranate and its Many Functional Components as Related to Human Health: A Review

(2010) M. Viuda-Martos et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Colon Cancer Chemopreventive Activities of Pomegranate Ellagitannins and Urolithins

(2010) Sashi G. Kasimsetty et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

(2010) Sander Michel Houten et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Ellagic acid protects hepatocytes from damage by inhibiting mitochondrial production of reactive oxygen species

(2009) Jung Me Hwang et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-microbial activities of pomegranate rind extracts: enhancement by cupric sulphate against clinical isolates of S. aureus, MRSA and PVL positive CA-MSSA

(2009) Simon WJ Gould et al.   BMC Complementary and Alternative Medicine

TNF-α, a potent lipid metabolism regulator

(2009) Xiuping Chen et al.   CELL BIOCHEMISTRY AND FUNCTION

Anti-inflammatory effects of Punica granatum Linne in vitro and in vivo

(2009) Chia-Jung Lee et al.   FOOD CHEMISTRY

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY

Punicic Acid from Trichosanthes kirilowii Seed Oil Is Rapidly Metabolized to Conjugated Linoleic Acid in Rats

(2009) Gao-Feng Yuan et al.   JOURNAL OF MEDICINAL FOOD

Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells

(2008) Mika Sekiya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diabetes-related metabolic perturbations in cardiac myocyte

(2008) D. Feuvray et al.   DIABETES & METABOLISM

Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels

(2008) L. Li et al.   DIABETES OBESITY & METABOLISM

Antidiabetic effect of Punica granatum flowers: Effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes

(2008) Priyanka Bagri et al.   FOOD AND CHEMICAL TOXICOLOGY

Pomegranate Phenolics from the Peels, Arils, and Flowers Are Antiatherogenic: Studiesin Vivoin Atherosclerotic Apolipoprotein E-Deficient (E0) Mice andin Vitroin Cultured Macrophages and Lipoproteins

(2008) Michael Aviram et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Medicinal Values of Fruit Peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with Respect to Alterations in Tissue Lipid Peroxidation and Serum Concentration of Glucose, Insulin, and Thyroid Hormones

(2008) Hamendra Singh Parmar et al.   JOURNAL OF MEDICINAL FOOD

Nuclear receptors, mitochondria and lipid metabolism

(2008) William A. Alaynick   MITOCHONDRION

Pomegranate juice: a heart-healthy fruit juice

(2008) Arpita Basu et al.   NUTRITION REVIEWS

The Nrf2–Keap1 defence pathway: Role in protection against drug-induced toxicity

(2007) Ian M. Copple et al.   TOXICOLOGY