Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in the Era of the Human Microbiome: Persistent Pathogens Drive Chronic Symptoms by Interfering With Host Metabolism, Gene Expression, and Immunity

Vaginal microbiota and susceptibility to HIV

(2018) McKenna C. Eastment et al.   AIDS

Implants induce a new niche for microbiomes

(2018) Tim H. Jakobsen et al.   APMIS

No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases

(2018) Douglas B. Kell et al.   BIOLOGICAL REVIEWS

The microbiome and autoimmunity: a paradigm from the gut–liver axis

(2018) Bo Li et al.   Cellular & Molecular Immunology

Does the microbiome and virome contribute to myalgic encephalomyelitis/chronic fatigue syndrome?

(2018) Fiona Newberry et al.   CLINICAL SCIENCE

Reaction of Amyloid-β Peptide Antibody with Different Infectious Agents Involved in Alzheimer’s Disease

(2018) Aristo Vojdani et al.   JOURNAL OF ALZHEIMERS DISEASE

Bacteriophages of the Urinary Microbiome

(2018) Taylor Miller-Ensminger et al.   JOURNAL OF BACTERIOLOGY

Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function

(2018) Shirin Hosseini et al.   JOURNAL OF NEUROSCIENCE

Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity

(2018) John B. Harley et al.   NATURE GENETICS

Current understanding of the human microbiome

(2018) Jack A Gilbert et al.   NATURE MEDICINE

Convergence of placenta biology and genetic risk for schizophrenia

(2018) Gianluca Ursini et al.   NATURE MEDICINE

Streptococcus pneumoniae: transmission, colonization and invasion

(2018) Jeffrey N. Weiser et al.   NATURE REVIEWS MICROBIOLOGY

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

(2018) William A. Eimer et al.   NEURON

Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

(2018) Trinitat Cambras et al.   PLoS One

The safety and quality of pork and poultry meat imports for the common European market received at border inspection post Hamburg Harbour between 2014 and 2015

(2018) Wiebke Jansen et al.   PLoS One

Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions

(2018) Emrah Altindis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

Translocation of a gut pathobiont drives autoimmunity in mice and humans

(2018) S. Manfredo Vieira et al.   SCIENCE

Archaea Are Interactive Components of Complex Microbiomes

(2018) Christine Moissl-Eichinger et al.   TRENDS IN MICROBIOLOGY

Culturing of female bladder bacteria reveals an interconnected urogenital microbiota

(2018) Krystal Thomas-White et al.   Nature Communications

The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression

(2018) Smruti Pushalkar et al.   Cancer Discovery

Infection of Fungi and Bacteria in Brain Tissue From Elderly Persons and Patients With Alzheimer’s Disease

(2018) Ruth Alonso et al.   Frontiers in Aging Neuroscience

Post-Ebola Syndrome among Ebola Virus Disease Survivors in Montserrado County, Liberia 2016

(2018) Himiede W. Wilson et al.   Biomed Research International

A selective gut bacterial bile salt hydrolase alters host metabolism

(2018) Lina Yao et al.   eLife

Identification and Characterization of Blood and Neutrophil-Associated Microbiomes in Patients with Severe Acute Pancreatitis Using Next-Generation Sequencing

(2018) Qiurong Li et al.   Frontiers in Cellular and Infection Microbiology

Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia

(2018) Loes M. Olde Loohuis et al.   Translational Psychiatry

Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model

(2018) Jonas Blomberg et al.   Frontiers in Immunology

Humans as holobionts: implications for prevention and therapy

(2018) Maarten van de Guchte et al.   Microbiome

Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia

(2018) Giuseppe Ercoli et al.   Nature Microbiology

The extracellular domain of Staphylococcus aureus LtaS binds insulin and induces insulin resistance during infection

(2018) Yu Liu et al.   Nature Microbiology

Murine colitis reveals a disease-associated bacteriophage community

(2018) Breck A. Duerkop et al.   Nature Microbiology

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

Function and functional redundancy in microbial systems

(2018) Stilianos Louca et al.   Nature Ecology & Evolution

Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease

(2018) Sandro Da Mesquita et al.   NATURE

Structure and Distribution of an Unrecognized Interstitium in Human Tissues

(2018) Petros C. Benias et al.   Scientific Reports

Parkinson’s disease and bacteriophages as its overlooked contributors

(2018) George Tetz et al.   Scientific Reports

AtopobiumandFusobacteriumas novel candidates for sarcoidosis-associated microbiota

(2017) Alexandra Zimmermann et al.   EUROPEAN RESPIRATORY JOURNAL

Myalgic encephalomyelitis/chronic fatigue syndrome and gulf war illness patients exhibit increased humoral responses to the herpesviruses-encoded dUTPase: Implications in disease pathophysiology

(2017) Peter Halpin et al.   JOURNAL OF MEDICAL VIROLOGY

Strains, functions and dynamics in the expanded Human Microbiome Project

(2017) Jason Lloyd-Price et al.   NATURE

The commensal lifestyle of Staphylococcus aureus and its interactions with the nasal microbiota

(2017) Bernhard Krismer et al.   NATURE REVIEWS MICROBIOLOGY

Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes

(2017) Martha Scott Tomlinson et al.   PLoS One

Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells

(2017) Gal Haimovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokine signature associated with disease severity in chronic fatigue syndrome patients

(2017) Jose G. Montoya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Numerous uncharacterized and highly divergent microbes which colonize humans are revealed by circulating cell-free DNA

(2017) Mark Kowarsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

(2017) Guoyan Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comorbidity in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Nationwide Population-Based Cohort Study

(2017) Jesús Castro-Marrero et al.   PSYCHOSOMATICS

Microbiota dysbiosis in select human cancers: Evidence of association and causality

(2017) Jie Chen et al.   SEMINARS IN IMMUNOLOGY

Characterization of the EBV-Induced Persistent DNA Damage Response

(2017) et al.   Viruses-Basel

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

(2017) Sophie Nguyen et al.   mBio

First Insights into the Diverse Human Archaeome: Specific Detection of Archaea in the Gastrointestinal Tract, Lung, and Nose and on Skin

(2017) Kaisa Koskinen et al.   mBio

The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases

(2017) Chen Chen et al.   Nature Communications

The blood DNA virome in 8,000 humans

(2017) Ahmed Moustafa et al.   PLoS Pathogens

HHV-6A/6B Infection of NK Cells Modulates the Expression of miRNAs and Transcription Factors Potentially Associated to Impaired NK Activity

(2017) Roberta Rizzo et al.   Frontiers in Microbiology

Methylation of the Vitamin D Receptor (VDR) Gene, Together with Genetic Variation, Race, and Environment Influence the Signaling Efficacy of the Toll-Like Receptor 2/1-VDR Pathway

(2017) Vanessa Meyer et al.   Frontiers in Immunology

Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome

(2017) Dorottya Nagy-Szakal et al.   Microbiome

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Diagnosis and Management in Young People: A Primer

(2017) Peter C. Rowe et al.   Frontiers in Pediatrics

Epigenetic Matters: The Link between Early Nutrition, Microbiome, and Long-term Health Development

(2017) Flavia Indrio et al.   Frontiers in Pediatrics

Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection

(2017) William A Fischer et al.   Open Forum Infectious Diseases

The Microbiota of Breast Tissue and Its Association with Breast Cancer

(2016) Camilla Urbaniak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome

(2016) Madlen Loebel et al.   BRAIN BEHAVIOR AND IMMUNITY

Comprehensive detection and identification of bacterial DNA in the blood of patients with sepsis and healthy volunteers using next-generation sequencing method - the observation of DNAemia

(2016) T. Gosiewski et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Microbes and Alzheimer’s Disease

(2016) Ruth F. Itzhaki et al.   JOURNAL OF ALZHEIMERS DISEASE

Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages

(2016) Michihiro Hashimoto et al.   JOURNAL OF IMMUNOLOGY

The Lung Microbiome, Immunity, and the Pathogenesis of Chronic Lung Disease

(2016) David N. O’Dwyer et al.   JOURNAL OF IMMUNOLOGY

Mortality of people with chronic fatigue syndrome: a retrospective cohort study in England and Wales from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Clinical Record Interactive Search (CRIS) Register

(2016) Emmert Roberts et al.   LANCET

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

(2016) G B Rogers et al.   MOLECULAR PSYCHIATRY

Uncovering Earth’s virome

(2016) David Paez-Espino et al.   NATURE

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

NCBI prokaryotic genome annotation pipeline

(2016) Tatiana Tatusova et al.   NUCLEIC ACIDS RESEARCH

IMG/VR: a database of cultured and uncultured DNA Viruses and retroviruses

(2016) David Paez-Espino et al.   NUCLEIC ACIDS RESEARCH

Extracellular vesicles and viruses: Are they close relatives?

(2016) Esther Nolte-‘t Hoen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic features of chronic fatigue syndrome

(2016) Robert K. Naviaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The epigenetic landscape of T cell exhaustion

(2016) D. R. Sen et al.   SCIENCE

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

The human milk microbiome and factors influencing its composition and activity

(2016) Carlos Gomez-Gallego et al.   Seminars in Fetal & Neonatal Medicine

Comprehensive description of blood microbiome from healthy donors assessed by 16S targeted metagenomic sequencing

(2016) Sandrine Païssé et al.   TRANSFUSION

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

(2016) Amy Langdon et al.   Genome Medicine

Microbial Changes during Pregnancy, Birth, and Infancy

(2016) Meital Nuriel-Ohayon et al.   Frontiers in Microbiology

Dysbiosis May Trigger Autoimmune Diseases via Inappropriate Post-Translational Modification of Host Proteins

(2016) Aaron Lerner et al.   Frontiers in Microbiology

Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome

(2016) Ludovic Giloteaux et al.   Microbiome

Research on the human virome: where are we and what is next

(2016) Shimian Zou et al.   Microbiome

Measles virus induces persistent infection by autoregulation of viral replication

(2016) Tomomitsu Doi et al.   Scientific Reports

Extensive Strain-Level Copy-Number Variation across Human Gut Microbiome Species

(2015) Sharon Greenblum et al.   CELL

Metabolism Links Bacterial Biofilms and Colon Carcinogenesis

(2015) Caroline H. Johnson et al.   Cell Metabolism

On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death

(2015) Douglas B. Kell et al.   Integrative Biology

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

(2015) Eoin F. McKinney et al.   NATURE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Crosstalk between the microbiome and cancer cells by quorum sensing peptides

(2015) Evelien Wynendaele et al.   PEPTIDES

Prion aggregates transfer through tunneling nanotubes in endocytic vesicles

(2015) Seng Zhu et al.   Prion

Right Arcuate Fasciculus Abnormality in Chronic Fatigue Syndrome

(2015) Michael M. Zeineh et al.   RADIOLOGY

Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality

(2015) M. J. Mina et al.   SCIENCE

Functional signatures of oral dysbiosis during periodontitis progression revealed by microbial metatranscriptome analysis

(2015) Susan Yost et al.   Genome Medicine

Distinct plasma immune signatures in ME/CFS are present early in the course of illness

(2015) M. Hornig et al.   Science Advances

The Characterization of Novel Tissue Microbiota Using an Optimized 16S Metagenomic Sequencing Pipeline

(2015) Jérôme Lluch et al.   PLoS One

Different Brain Regions are Infected with Fungi in Alzheimer’s Disease

(2015) Diana Pisa et al.   Scientific Reports

Managing Cytokine Release Syndrome Associated With Novel T Cell-Engaging Therapies

(2014) Shannon L. Maude et al.   CANCER JOURNAL

Defining dysbiosis and its influence on host immunity and disease

(2014) Charisse Petersen et al.   CELLULAR MICROBIOLOGY

Helicobacter pylori Infection Introduces DNA Double-Strand Breaks in Host Cells

(2014) Katsuhiro Hanada et al.   INFECTION AND IMMUNITY

Transcriptome Analysis Reveals Human Cytomegalovirus Reprograms Monocyte Differentiation toward an M1 Macrophage

(2014) G. Chan et al.   JOURNAL OF IMMUNOLOGY

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Enteric bacteria promote human and mouse norovirus infection of B cells

(2014) M. K. Jones et al.   SCIENCE

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

The status of and future research into Myalgic Encephalomyelitis and Chronic Fatigue Syndrome: the need of accurate diagnosis, objective assessment, and acknowledging biological and clinical subgroups

(2014) Frank N. M. Twisk   Frontiers in Physiology

High-throughput 16S rRNA gene sequencing reveals alterations of intestinal microbiota in myalgic encephalomyelitis/chronic fatigue syndrome patients

(2013) Marc Frémont et al.   ANAEROBE

Reprogramming Adult Schwann Cells to Stem Cell-like Cells by Leprosy Bacilli Promotes Dissemination of Infection

(2013) Toshihiro Masaki et al.   CELL

Transplantation-Associated Long-Term Immunosuppression Promotes Oral Colonization by Potentially Opportunistic Pathogens without Impacting Other Members of the Salivary Bacteriome

(2013) Patricia I. Diaz et al.   Clinical and Vaccine Immunology

The human microbiome and autoimmunity

(2013) Amy D. Proal et al.   CURRENT OPINION IN RHEUMATOLOGY

Immunostimulation in the treatment for chronic fatigue syndrome/myalgic encephalomyelitis

(2013) Amy D. Proal et al.   IMMUNOLOGIC RESEARCH

HIV and co-infections

(2013) Christina C. Chang et al.   IMMUNOLOGICAL REVIEWS

Chronic fatigue syndrome from vagus nerve infection: A psychoneuroimmunological hypothesis

(2013) Michael B. VanElzakker   MEDICAL HYPOTHESES

Tumour heterogeneity in the clinic

(2013) Philippe L. Bedard et al.   NATURE

Brain Microbial Populations in HIV/AIDS: α-Proteobacteria Predominate Independent of Host Immune Status

(2013) William G. Branton et al.   PLoS One

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

(2013) Jennifer L. Pluznick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging world of the fungal microbiome

(2013) Gary B. Huffnagle et al.   TRENDS IN MICROBIOLOGY

Bacterial Adaptation through Loss of Function

(2013) Alison K. Hottes et al.   PLoS Genetics

The Genetic Basis of Escherichia coli Pathoadaptation to Macrophages

(2013) Migla Miskinyte et al.   PLoS Pathogens

The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery

(2012) Raul Cabrera-Rubio et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Effect ofAspergillus fumigatusInfection on Vitamin D Receptor Expression in Cystic Fibrosis

(2012) Catherine A. Coughlan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

HIV & immune reconstitution inflammatory syndrome (IRIS)

(2012) SurendraK Sharma et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

Hijacking Mitochondria: Bacterial Toxins that Modulate Mitochondrial Function

(2012) Jhih-Hang Jiang et al.   IUBMB LIFE

MicroRNA-21 targets the vitamin D–dependent antimicrobial pathway in leprosy

(2012) Philip T Liu et al.   NATURE MEDICINE

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Immunostimulation in the era of the metagenome

(2011) Amy D Proal et al.   Cellular & Molecular Immunology

Multidrug-Resistant Enterococci in Animal Meat and Faeces and Co-Transfer of Resistance from an Enterococcus durans to a Human Enterococcus faecium

(2011) Carla Vignaroli et al.   CURRENT MICROBIOLOGY

Pathobionts of the gastrointestinal microbiota and inflammatory disease

(2011) Janet Chow et al.   CURRENT OPINION IN IMMUNOLOGY

Moving pictures of the human microbiome

(2011) J Gregory Caporaso et al.   GENOME BIOLOGY

Immune reconstitution inflammatory syndrome in patients starting antiretroviral therapy for HIV infection: a systematic review and meta-analysis

(2010) Monika Müller et al.   LANCET INFECTIOUS DISEASES

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome and Unmasking of Tuberculosis by Antiretroviral Therapy

(2009) Graeme Meintjes et al.   CLINICS IN CHEST MEDICINE

Human Pathogens Abundant in the Bacterial Metagenome of Cigarettes

(2009) Amy R. Sapkota et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

BAK1 gene variation and abdominal aortic aneurysms

(2009) Bruce Gottlieb et al.   HUMAN MUTATION

Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence

(2009) J. Chia et al.   JOURNAL OF CLINICAL PATHOLOGY

The human superorganism – Of microbes and men

(2009) Roy D. Sleator   MEDICAL HYPOTHESES

Antimicrobial Activity of Human Prion Protein Is Mediated by Its N-Terminal Region

(2009) Mukesh Pasupuleti et al.   PLoS One

Insights into the Molecular Basis of L-Form Formation and Survival in Escherichia coli

(2009) William A. Glover et al.   PLoS One

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opportunistic pathogens enriched in showerhead biofilms

(2009) L. M. Feazel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

(2009) Juan C. Salazar et al.   PLoS Pathogens

Chronic Fatigue Syndrome after Human Parvovirus B19 Infection without Persistent Viremia

(2008) Mariko Seishima et al.   DERMATOLOGY