Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia

Splenic Ly6G high mature and Ly6G int immature neutrophils contribute to eradication of S. pneumoniae

(2017) Justin F. Deniset et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pneumococcal colonization and invasive disease studied in a porcine model

(2016) Astrid de Greeff et al.   BMC MICROBIOLOGY

Identification and treatment of the Staphylococcus aureus reservoir in vivo

(2016) Bas G.J. Surewaard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single Cell Bottlenecks in the Pathogenesis of Streptococcus pneumoniae

(2016) Masamitsu Kono et al.   PLoS Pathogens

Overwhelming Postsplenectomy Infection: A Prospective Multicenter Cohort Study

(2015) Christian Theilacker et al.   CLINICAL INFECTIOUS DISEASES

Antigen targeting reveals splenic CD169+macrophages as promoters of germinal center B-cell responses

(2015) Henrike Veninga et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human spleen microanatomy: why mice do not suffice

(2015) Birte S. Steiniger   IMMUNOLOGY

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

(2015) Sophie M. Lehar et al.   NATURE

British Thoracic Society community acquired pneumonia guideline and the NICE pneumonia guideline: how they fit together

(2015) W. S. Lim et al.   THORAX

Bright Fluorescent Streptococcus pneumoniae for Live-Cell Imaging of Host-Pathogen Interactions

(2014) Morten Kjos et al.   JOURNAL OF BACTERIOLOGY

Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

(2014) Yung-Chi Chang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Community-Acquired Pneumonia

(2014) Daniel M. Musher et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pneumolysin Activates Macrophage Lysosomal Membrane Permeabilization and Executes Apoptosis by Distinct Mechanisms without Membrane Pore Formation

(2014) M. A. Bewley et al.   mBio

The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck

(2014) Alice Gerlini et al.   PLoS Pathogens

A Bacterial Virulence Protein Promotes Pathogenicity by Inhibiting the Bacterium’s Own F1Fo ATP Synthase

(2013) Eun-Jin Lee et al.   CELL

Phenotypic and functional heterogeneity of CD169+ and CD163+ macrophages from porcine lymph nodes and spleen

(2013) Belén Alvarez et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Enhanced, Sialoadhesin-Dependent Uptake of Guillain-Barré Syndrome-Associated Campylobacter jejuni Strains by Human Macrophages

(2013) Astrid P. Heikema et al.   INFECTION AND IMMUNITY

Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells

(2013) W. Van Breedam et al.   JOURNAL OF GENERAL VIROLOGY

The fundamental link between pneumococcal carriage and disease

(2012) Birgit Simell et al.   Expert Review of Vaccines

Sialoadhesin Promotes Rapid Proinflammatory and Type I IFN Responses to a Sialylated Pathogen, Campylobacter jejuni

(2012) M. Klaas et al.   JOURNAL OF IMMUNOLOGY

Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice

(2011) Kimberly M. Davis et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex-Based Differences in Susceptibility to Respiratory and Systemic Pneumococcal Disease in Mice

(2011) Aras Kadioglu et al.   JOURNAL OF INFECTIOUS DISEASES

The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease

(2011) Lynsey Fairbairn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

(2011) Nadine Honke et al.   NATURE IMMUNOLOGY

The pig: a model for human infectious diseases

(2011) François Meurens et al.   TRENDS IN MICROBIOLOGY

Characterization of the Specific Interaction between Sialoadhesin and Sialylated Campylobacter jejuni Lipooligosaccharides

(2010) A. P. Heikema et al.   INFECTION AND IMMUNITY

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion

(2009) Satoshi Uchiyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells

(2009) R. Backer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Porcine myelomonocytic markers and cell populations

(2008) A. Ezquerra et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A dynamic view of the spread and intracellular distribution of Salmonella enterica

(2008) Pietro Mastroeni et al.   NATURE REVIEWS MICROBIOLOGY

Modelling within-Host Spatiotemporal Dynamics of Invasive Bacterial Disease

(2008) Andrew J Grant et al.   PLOS BIOLOGY