Characterization of the EBV-Induced Persistent DNA Damage Response

Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection

(2017) Alexander M Price et al.   eLife

Limited nucleotide pools restrict Epstein–Barr virus-mediated B-cell immortalization

(2017) A Y Hafez et al.   Oncogenesis

Danazol Treatment for Telomere Diseases

(2016) Danielle M. Townsley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolic stress is a barrier to Epstein–Barr virus-mediated B-cell immortalization

(2016) Karyn McFadden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Derepression ofhTERTgene expression promotes escape from oncogene-induced cellular senescence

(2016) Priyanka L. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitogen-Induced B-Cell Proliferation Activates Chk2-Dependent G1/S Cell Cycle Arrest

(2014) Pavel A. Nikitin et al.   PLoS One

Stable Cellular Senescence Is Associated with Persistent DDR Activation

(2014) Marzia Fumagalli et al.   PLoS One

STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation

(2014) Siva Koganti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

(2014) Sujoy Chatterjee et al.   Nature Communications

A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

(2013) Giang Huong Nguyen et al.   CHEMISTRY & BIOLOGY

Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein–Barr virus

(2013) S A Kamranvar et al.   ONCOGENE

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

(2012) Anitha Suram et al.   EMBO JOURNAL

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

(2012) Marzia Fumagalli et al.   NATURE CELL BIOLOGY

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

(2012) Graeme Hewitt et al.   Nature Communications

Replication stress induces 53BP1-containing OPT domains in G1 cells

(2011) Jeanine A. Harrigan et al.   JOURNAL OF CELL BIOLOGY

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

An ATM/Chk2-Mediated DNA Damage-Responsive Signaling Pathway Suppresses Epstein-Barr Virus Transformation of Primary Human B Cells

(2010) Pavel A. Nikitin et al.   Cell Host & Microbe

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

(2010) F. Rodier et al.   JOURNAL OF CELL SCIENCE

Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells

(2009) R. T. Calado et al.   BLOOD

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY