Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2

Structure of a volume-regulated anion channel of the LRRC8 family

(2018) Dawid Deneka et al.   NATURE

Structure of the mechanosensitive OSCA channels

(2018) Mingfeng Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels

(2018) Swetha E Murthy et al.   eLife

Cryo-EM structure of the mechanically activated ion channel OSCA1.2

(2018) Sebastian Jojoa-Cruz et al.   eLife

Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM

(2017) Cristina Paulino et al.   NATURE

Cryo-EM structures of the TMEM16A calcium-activated chloride channel

(2017) Shangyu Dang et al.   NATURE

Structure of the mechanically activated ion channel Piezo1

(2017) Kei Saotome et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A

(2017) Cristina Paulino et al.   eLife

Structure-based membrane dome mechanism for Piezo mechanosensitivity

(2017) Yusong R Guo et al.   eLife

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength

(2016) Ruhma Syeda et al.   CELL

Co-expression of mouse TMEM63A, TMEM63B and TMEM63C confers hyperosmolarity activated ion currents in HEK293 cells

(2016) Xin Zhao et al.   CELL BIOCHEMISTRY AND FUNCTION

Structural basis for phospholipid scrambling in the TMEM16 family

(2016) Janine D Brunner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A

(2016) Novandy K. Lim et al.   JOURNAL OF GENERAL PHYSIOLOGY

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

From membrane tension to channel gating: A principal energy transfer mechanism for mechanosensitive channels

(2016) Xuejun C. Zhang et al.   PROTEIN SCIENCE

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Genome-wide survey and expression analysis of the OSCA gene family in rice

(2015) Yunshuang Li et al.   BMC PLANT BIOLOGY

Mechanisms of mechanosensing — mechanosensitive channels, function and re-engineering

(2015) Armagan Kocer   CURRENT OPINION IN CHEMICAL BIOLOGY

Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage

(2015) Xueming Li et al.   JOURNAL OF STRUCTURAL BIOLOGY

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

The role of lipids in mechanosensation

(2015) Christos Pliotas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Transporter Classification Database (TCDB): recent advances

(2015) Milton H. Saier et al.   NUCLEIC ACIDS RESEARCH

The role of lipids in mechanosensation

(2015) Christos Pliotas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes

(2014) Congcong Hou et al.   CELL RESEARCH

X-ray structure of a calcium-activated TMEM16 lipid scramblase

(2014) Janine D. Brunner et al.   NATURE

OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing in Arabidopsis

(2014) Fang Yuan et al.   NATURE

Force Transduction and Lipid Binding in MscL: A Continuum-Molecular Approach

(2014) Juan M. Vanegas et al.   PLoS One

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Plant mechanosensing and Ca2+ transport

(2013) Takamitsu Kurusu et al.   TRENDS IN PLANT SCIENCE

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Bacterial Mechanosensitive Channels—MscS: Evolution's Solution to Creating Sensitivity in Function

(2012) James H. Naismith et al.   Annual Review of Biophysics

Plasma membrane protein OsMCA1 is involved in regulation of hypo-osmotic shock-induced Ca2+ influx and modulates generation of reactive oxygen species in cultured rice cells

(2012) Takamitsu Kurusu et al.   BMC PLANT BIOLOGY

Membrane Topology and Predicted RNA-Binding Function of the ‘Early Responsive to Dehydration (ERD4)’ Plant Protein

(2012) Archana Rai et al.   PLoS One

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Canonical TRP channels and mechanotransduction: from physiology to disease states

(2010) Amanda Patel et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Local calcium signals induced by hyper-osmotic stress in mammalian skeletal muscle cells

(2009) Simona Apostol et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Two MscS Homologs Provide Mechanosensitive Channel Activities in the Arabidopsis Root

(2008) Elizabeth S. Haswell et al.   CURRENT BIOLOGY

Shaping the calcium signature

(2008) Martin R. McAinsh et al.   NEW PHYTOLOGIST

The Structure of an Open Form of an E. coli Mechanosensitive Channel at 3.45 A Resolution

(2008) W. Wang et al.   SCIENCE