The role of lipids in mechanosensation

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

(2015) Koji Tanaka et al.   Nature Communications

Probing the Structure of the Mechanosensitive Channel of Small Conductance in Lipid Bilayers with Pulsed Electron-Electron Double Resonance

(2014) Richard Ward et al.   BIOPHYSICAL JOURNAL

Bacterial mechanosensitive channels: progress towards an understanding of their roles in cell physiology

(2014) Ian R Booth   CURRENT OPINION IN MICROBIOLOGY

Membrane proteins bind lipids selectively to modulate their structure and function

(2014) Arthur Laganowsky et al.   NATURE

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

(2014) Stephen G. Brohawn et al.   NATURE

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

(2014) Jinfeng Teng et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Piezo channels: from structure to function

(2014) Linda Volkers et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+channels

(2014) Stephen G. Brohawn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Feeling the hidden mechanical forces in lipid bilayer is an original sense

(2014) A. Anishkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ThePDB_REDOserver for macromolecular structure model optimization

(2014) Robbie P. Joosten et al.   IUCrJ

Better models by discarding data?

(2013) K. Diederichs et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanosensitive channels and bacterial cell wall integrity: does life end with a bang or a whimper?

(2013) M. Reuter et al.   Journal of the Royal Society Interface

Quantification of free cysteines in membrane and soluble proteins using a fluorescent dye and thermal unfolding

(2013) Emma Branigan et al.   Nature Protocols

Stiffened lipid platforms at molecular force foci

(2013) A. Anishkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Open and shut: Crystal structures of the dodecylmaltoside solubilized mechanosensitive channel of small conductance fromEscherichia coliandHelicobacter pyloriat 4.4 Å and 4.1 Å resolutions

(2013) Jeffrey Y. Lai et al.   PROTEIN SCIENCE

Selectivity mechanism of the mechanosensitive channel MscS revealed by probing channel subconducting states

(2013) C. D. Cox et al.   Nature Communications

Bacterial Mechanosensitive Channels—MscS: Evolution's Solution to Creating Sensitivity in Function

(2012) James H. Naismith et al.   Annual Review of Biophysics

Sensing and Responding to Membrane Tension: The Bacterial MscL Channel as a Model System

(2012) Irene Iscla et al.   BIOPHYSICAL JOURNAL

Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS

(2012) T. Nomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy

(2012) C. Pliotas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K+ channels

(2012) D. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

(2012) S. G. Brohawn et al.   SCIENCE

Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1

(2012) A. N. Miller et al.   SCIENCE

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Bacterial Mechanosensitive Channels as a Paradigm for Mechanosensory Transduction

(2011) Boris Martinac   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

From Coarse Grained to Atomistic: A Serial Multiscale Approach to Membrane Protein Simulations

(2011) Phillip J. Stansfeld et al.   Journal of Chemical Theory and Computation

Mechanosensitive Channels: What Can They Do and How Do They Do It?

(2011) Elizabeth S. Haswell et al.   STRUCTURE

Biological membranes: the importance of molecular detail

(2011) Anthony G. Lee   TRENDS IN BIOCHEMICAL SCIENCES

Eukaryotic Mechanosensitive Channels

(2010) Jóhanna Árnadóttir et al.   Annual Review of Biophysics

Mechanosensitive Channels in Microbes

(2010) Ching Kung et al.   Annual Review of Microbiology

Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei

(2010) GREGORY S. RICHMOND et al.   PARASITOLOGY

YbdG inEscherichia coliis a threshold-setting mechanosensitive channel with MscM activity

(2010) Ulrike Schumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tryptophan in the Pore of the Mechanosensitive Channel MscS

(2009) Tim Rasmussen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation

(2009) Andriy Anishkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles for lipids in shaping membrane-protein function

(2009) Rob Phillips et al.   NATURE

PoreWalker: A Novel Tool for the Identification and Characterization of Channels in Transmembrane Proteins from Their Three-Dimensional Structure

(2009) Marialuisa Pellegrini-Calace et al.   PLoS Computational Biology

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Mechanosensitive Channel MscS in the Open State: Modeling of the Transition, Explicit Simulations, and Experimental Measurements of Conductance

(2008) Andriy Anishkin et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Structure of an Open Form of an E. coli Mechanosensitive Channel at 3.45 A Resolution

(2008) W. Wang et al.   SCIENCE

A Structural Mechanism for MscS Gating in Lipid Bilayers

(2008) V. Vasquez et al.   SCIENCE

Coarse-Grained MD Simulations of Membrane Protein-Bilayer Self-Assembly

(2008) Kathryn A. Scott et al.   STRUCTURE