Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation

Residual Inflammatory Risk on Treatment With PCSK9 Inhibition and Statin Therapy

(2018) Aruna D. Pradhan et al.   CIRCULATION

Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moietyin vitroandin vivo: Implication in atherosclerosis

(2017) Jianhong Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of foam cell formation in atherosclerosis

(2017) Dimitry A. Chistiakov et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Role of Rab5 in the formation of macrophage-derived foam cell

(2017) Lokwern Chan et al.   Lipids in Health and Disease

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

(2017) Chen-Song Zhang et al.   NATURE

Advances in new therapeutic targets for atherosclerosis

(2017) W. H. Wilson Tang et al.   Nature Reviews Cardiology

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

(2017) Ismail Sergin et al.   Nature Communications

Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction

(2017) Juan Tang et al.   Nature Communications

Familial hypercholesterolaemia

(2017) Joep C. Defesche et al.   Nature Reviews Disease Primers

Do theApoe−/−andLdlr−/–Mice Yield the Same Insight on Atherogenesis?Highlights: Table.

(2016) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prostaglandin E2promotes hepatic bile acid synthesis by an E prostanoid receptor 3-mediated hepatocyte nuclear receptor 4α/cholesterol 7α-hydroxylase pathway in mice

(2016) Shuai Yan et al.   HEPATOLOGY

Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque

(2016) Chang Pan et al.   Oncotarget

Degradation and beyond

(2015) Ismail Sergin et al.   CURRENT OPINION IN LIPIDOLOGY

Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial

(2015) Frederick J Raal et al.   LANCET

ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis

(2015) Shengfang Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aldehyde dehydrogenase-2 protects against myocardial infarction-related cardiac fibrosis through modulation of the Wnt/β-catenin signaling pathway

(2015) Yingchun Zhou et al.   Therapeutics and Clinical Risk Management

Metformin Inhibits Monocyte-to-Macrophage Differentiation via AMPK-Mediated Inhibition of STAT3 Activation: Potential Role in Atherosclerosis

(2015) Sathish Babu Vasamsetti et al.   DIABETES

Association between Glu504Lys Polymorphism of ALDH2 Gene and Cancer Risk: A Meta-Analysis

(2015) Qiang Cai et al.   PLoS One

V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation

(2014) Oliver Florey et al.   Autophagy

Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling

(2014) Katia M.S. Gomes et al.   CARDIOVASCULAR RESEARCH

AAV Vectors Expressing LDLR Gain-of-Function Variants Demonstrate Increased Efficacy in Mouse Models of Familial Hypercholesterolemia

(2014) Suryanarayan Somanathan et al.   CIRCULATION RESEARCH

ALDH2, a novel protector against stroke?

(2013) Aijun Sun et al.   CELL RESEARCH

ALDH2 protects against stroke by clearing 4-HNE

(2013) Jin-Min Guo et al.   CELL RESEARCH

Association of genetic polymorphisms in ADH and ALDH2 with risk of coronary artery disease and myocardial infarction: A meta-analysis

(2013) Hongguang Han et al.   GENE

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

(2012) Annika Höhn et al.   FREE RADICAL BIOLOGY AND MEDICINE

A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

(2012) Min Yuan et al.   Nature Protocols

V-ATPase engagement in autophagic processes

(2011) Dalibor Mijaljica et al.   Autophagy

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Malondialdehyde inhibits an AMPK-mediated nuclear translocation and repression activity of ALDH2 in transcription

(2010) Ji-Woong Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial aldehyde dehydrogenase and cardiac diseases

(2010) Che-Hong Chen et al.   CARDIOVASCULAR RESEARCH

Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde

(2010) Heng Ma et al.   EUROPEAN HEART JOURNAL

Refined Geographic Distribution of the OrientalALDH2*504Lys(nee487Lys) Variant

(2009) Hui Li et al.   ANNALS OF HUMAN GENETICS

P68 RNA helicase is a nucleocytoplasmic shuttling protein

(2009) Haizhen Wang et al.   CELL RESEARCH