Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling

Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities

(2014) Che-Hong Chen et al.   PHYSIOLOGICAL REVIEWS

Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models

(2013) Hussain Contractor et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health

(2012) Tiago R. Figueira et al.   ANTIOXIDANTS & REDOX SIGNALING

Lipid peroxidation dysregulation in ischemic stroke: Plasma 4-HNE as a potential biomarker?

(2012) Wan-Chi Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease

(2012) Hao Zhang et al.   EUROPEAN HEART JOURNAL

An Update on Cardioprotection

(2012) Paul Z. Gerczuk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondria as a Therapeutic Target in Heart Failure

(2012) Marina Bayeva et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Protein Quality Control Disruption by PKCβII in Heart Failure; Rescue by the Selective PKCβII Inhibitor, βIIV5-3

(2012) Julio C. B. Ferreira et al.   PLoS One

Exercise Training Restores Cardiac Protein Quality Control in Heart Failure

(2012) Juliane C. Campos et al.   PLoS One

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

Nitroglycerin Use in Myocardial Infarction Patients

(2011) Julio C.B. Ferreira et al.   CIRCULATION JOURNAL

Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy

(2011) Julio C.B. Ferreira et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ALDH2 Activator Inhibits Increased Myocardial Infarction Injury by Nitroglycerin Tolerance

(2011) L. Sun et al.   Science Translational Medicine

Mitochondrial aldehyde dehydrogenase and cardiac diseases

(2010) Che-Hong Chen et al.   CARDIOVASCULAR RESEARCH

Aerobic exercise training improves skeletal muscle function and Ca2+ handling-related protein expression in sympathetic hyperactivity-induced heart failure

(2010) C. R. Bueno et al.   JOURNAL OF APPLIED PHYSIOLOGY

PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses

(2010) Suresh Selvaraj Palaniyandi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: Role of protein phosphatases

(2010) Heng Ma et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant

(2010) Samantha Perez-Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal

(2009) Bradford G. Hill et al.   BIOCHEMICAL JOURNAL

Ischaemic preconditioning improves proteasomal activity and increases the degradation of  PKC during reperfusion

(2009) E. N. Churchill et al.   CARDIOVASCULAR RESEARCH

Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCɛ) knockout mice

(2009) Grant R. Budas et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Aldehyde Dehydrogenase 2 in Cardiac Protection: A New Therapeutic Target?

(2009) Grant R. Budas et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Myocardial ischaemia inhibits mitochondrial metabolism of 4-hydroxy-trans-2-nonenal

(2008) Bradford G. Hill et al.   BIOCHEMICAL JOURNAL

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

(2008) Che-Hong Chen et al.   SCIENCE