- Home
- Publications
- Publication Search
- Publication Details
Title
p62/SQSTM1 – steering the cell through health and disease
Authors
Keywords
-
Journal
JOURNAL OF CELL SCIENCE
Volume 131, Issue 21, Pages jcs222836
Publisher
The Company of Biologists
Online
2018-11-05
DOI
10.1242/jcs.222836
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway
- (2018) Hyunjoo Cha-Molstad et al. Autophagy
- Autophagy-mediated upregulation of cytoplasmic claudin 1 stimulates the degradation of SQSTM1/p62 under starvation
- (2018) Jaewhan Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity
- (2018) Alexia F. Kalogeropulou et al. BIOCHEMICAL JOURNAL
- Nrf2-Keap1 signaling in oxidative and reductive stress
- (2018) Ilaria Bellezza et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor
- (2018) Jianfeng Huang et al. CANCER CELL
- Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
- (2018) Tatsuya Yamada et al. Cell Metabolism
- Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation
- (2018) Daxiao Sun et al. CELL RESEARCH
- Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
- (2018) Sarah Pickles et al. CURRENT BIOLOGY
- p62 filaments capture and present ubiquitinated cargos for autophagy
- (2018) Gabriele Zaffagnini et al. EMBO JOURNAL
- Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis
- (2018) Kentaro Akiyama et al. EXPERIMENTAL ANIMALS
- Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
- (2018) Jakob Mejlvang et al. JOURNAL OF CELL BIOLOGY
- Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes
- (2018) Natalia Rodriguez-Muela et al. JOURNAL OF CLINICAL INVESTIGATION
- Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant
- (2018) Shun Kageyama et al. MOLECULAR AND CELLULAR BIOLOGY
- Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease
- (2018) Ningjing Huang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- A brief history of autophagy from cell biology to physiology and disease
- (2018) Noboru Mizushima NATURE CELL BIOLOGY
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner
- (2018) Maoping Tang et al. NEUROBIOLOGY OF AGING
- TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities
- (2018) Constanza J. Cortes et al. NEUROBIOLOGY OF DISEASE
- Autophagy as a common pathway in amyotrophic lateral sclerosis
- (2018) Dao K.H. Nguyen et al. NEUROSCIENCE LETTERS
- Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition
- (2018) Chao Shi et al. ONCOGENE
- Expression and Clinical Implication of Autophagy-Associated Protein p62 in Osteosarcoma
- (2018) Hangzhan Ma et al. ONCOLOGY
- N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis
- (2018) Young Dong Yoo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis
- (2018) Bernadette Carroll et al. Nature Communications
- DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma
- (2018) Yuki Mizuno et al. Scientific Reports
- High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
- (2018) In-geun Ryoo et al. Redox Biology
- p62-dependent phase separation of patient-derived KEAP1 mutations and NRF2
- (2018) E. W. Cloer et al. MOLECULAR AND CELLULAR BIOLOGY
- Cereblon suppresses the formation of pathogenic protein aggregates in a p62-dependent manner
- (2017) Liang Zhou et al. HUMAN MOLECULAR GENETICS
- Monitoring and Measuring Autophagy
- (2017) Saori R. Yoshii et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Galectin-8–mediated selective autophagy protects against seeded tau aggregation
- (2017) Benjamin Falcon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells
- (2017) Shinwon Ha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy
- (2017) Qiong Lin et al. JOURNAL OF CELL SCIENCE
- Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer
- (2017) Palak Shah et al. MOLECULES
- VPS34 stimulation of p62 phosphorylation for cancer progression
- (2017) X Jiang et al. ONCOGENE
- Distinct roles for motor neuron autophagy early and late in the SOD1G93Amouse model of ALS
- (2017) Noam D. Rudnick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multifunctional p62 Effects Underlie Diverse Metabolic Diseases
- (2017) Min Long et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Autophagy in Measles Virus Infection
- (2017) Aurore Rozières et al. Viruses-Basel
- Distinct Contributions of Autophagy Receptors in Measles Virus Replication
- (2017) Denitsa Petkova et al. Viruses-Basel
- p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis
- (2017) Hyunjoo Cha-Molstad et al. Nature Communications
- Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer
- (2017) Monique Niklaus et al. Oncotarget
- The prognostic value of p62 in solid tumor patients: a meta-analysis
- (2017) Haihua Ruan et al. Oncotarget
- Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors
- (2017) Dmitry M. Ponomarenko et al. Oncotarget
- Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination
- (2017) YouJin Lee et al. Cell Reports
- TBK1: a new player in ALS linking autophagy and neuroinflammation
- (2017) James A. Oakes et al. Molecular Brain
- The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease
- (2017) Elisabeth Stürner et al. Frontiers in Molecular Neuroscience
- Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture
- (2017) Yucel Aydin et al. Scientific Reports
- TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1
- (2016) Kazunori Hashimoto et al. ANTIOXIDANTS & REDOX SIGNALING
- HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis
- (2016) Yoshihisa Watanabe et al. Autophagy
- Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD
- (2016) Alice Goode et al. Autophagy
- Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells
- (2016) Haishan Huang et al. Autophagy
- p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
- (2016) Angeles Duran et al. CANCER CELL
- p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells
- (2016) Atsushi Umemura et al. CANCER CELL
- An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport
- (2016) Marlieke L.M. Jongsma et al. CELL
- Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis
- (2016) Da Hyun Lee et al. FREE RADICAL BIOLOGY AND MEDICINE
- Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice
- (2016) Shinji Hadano et al. HUMAN MOLECULAR GENETICS
- Enhanced p62 Is Responsible for Mitochondrial Pathway-Dependent Apoptosis and Interleukin-1β Production at the Early Phase by Monosodium Urate Crystals in Murine Macrophage
- (2016) Seong-Kyu Kim et al. INFLAMMATION
- Accumulation of phosphorylated p62 is associated with NF-E2-related factor 2 activation in hepatocellular carcinoma
- (2016) Takayuki Shimizu et al. Journal of Hepato-Biliary-Pancreatic Sciences
- LRRK2 interferes with aggresome formation for autophagic clearance
- (2016) Yeojin Bang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis
- (2016) Ji-An Pan et al. MOLECULAR CELL
- p62 improves AD-like pathology by increasing autophagy
- (2016) A Caccamo et al. MOLECULAR PSYCHIATRY
- Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro
- (2016) Carolin Walter et al. NEUROPHARMACOLOGY
- Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases
- (2016) Masaru Kurosawa et al. NEUROSCIENCE RESEARCH
- p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA
- (2016) L-Z Xu et al. ONCOGENE
- Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis
- (2016) Ismail Sergin et al. Science Signaling
- p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
- (2016) Tetsuya Saito et al. Nature Communications
- Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer
- (2016) Anna M. Schläfli et al. Oncotarget
- Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas
- (2016) Olivia Adams et al. Oncotarget
- Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming
- (2016) Irene Riz et al. Oncotarget
- Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease
- (2016) Pingping Song et al. Protein & Cell
- Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis
- (2016) Ismail Sergin et al. Science Signaling
- Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy
- (2016) Sangwook Park et al. PLoS One
- Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity
- (2015) Jeong Su Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
- (2015) Xiaofang Sun et al. HEPATOLOGY
- Ubiquitin conjugating enzyme E2-N and sequestosome-1 (p62) are components of the ubiquitination process mediated by the malin–laforin E3-ubiquitin ligase complex
- (2015) Pablo Sánchez-Martín et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells
- (2015) A. Eino et al. JOURNAL OF CELL SCIENCE
- Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy
- (2015) Davor Ivankovic et al. JOURNAL OF NEUROCHEMISTRY
- Autophagy in adipose tissue of patients with obesity and type 2 diabetes
- (2015) J. Kosacka et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress
- (2015) Huikyong Lee et al. MOLECULAR NEUROBIOLOGY
- Huntingtin functions as a scaffold for selective macroautophagy
- (2015) Yan-Ning Rui et al. NATURE CELL BIOLOGY
- NRF2 regulates serine biosynthesis in non–small cell lung cancer
- (2015) Gina M DeNicola et al. NATURE GENETICS
- SQSTM1splice site mutation in distal myopathy with rimmed vacuoles
- (2015) Robert C. Bucelli et al. NEUROLOGY
- Autophagy in Huntington disease and huntingtin in autophagy
- (2015) Dale D.O. Martin et al. TRENDS IN NEUROSCIENCES
- Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent
- (2015) Maria Giovanna Sabbieti et al. Oncotarget
- Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade
- (2015) Juan F. Linares et al. Cell Reports
- The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
- (2015) Rodolfo Ciuffa et al. Cell Reports
- Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates
- (2015) Junghyun Lim et al. PLoS Genetics
- Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector
- (2015) Franco Venanzi et al. Oncotarget
- Pilot study of p62 DNA vaccine in dogs with mammary tumors
- (2015) Vladimir Gabai et al. Oncotarget
- High Expression of SQSTM1/p62 Protein Is Associated with Poor Prognosis in Epithelial Ovarian Cancer
- (2014) Reiko Iwadate et al. ACTA HISTOCHEMICA ET CYTOCHEMICA
- Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function
- (2014) Alice Goode et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding
- (2014) Frank Christian et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- p62 Deficiency Enhances α-Synuclein Pathology in Mice
- (2014) Kunikazu Tanji et al. BRAIN PATHOLOGY
- Prognostic significance of p62/SQSTM1 subcellular localization and LC3B in oral squamous cell carcinoma
- (2014) J-L Liu et al. BRITISH JOURNAL OF CANCER
- Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
- (2014) Tania Valencia et al. CANCER CELL
- Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages
- (2014) Mario Kratz et al. Cell Metabolism
- SQSTM1 mutations – Bridging Paget disease of bone and ALS/FTLD
- (2014) Sarah L. Rea et al. EXPERIMENTAL CELL RESEARCH
- p62/SQSTM1 is involved in cisplatin resistance in human ovarian cancer cells via the Keap1-Nrf2-ARE system
- (2014) MEIHUI XIA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Interaction of SQSTM1 with the motor protein dynein - SQSTM1 is required for normal dynein function and trafficking
- (2014) L. Calderilla-Barbosa et al. JOURNAL OF CELL SCIENCE
- Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy
- (2014) Hong-Min Ni et al. JOURNAL OF HEPATOLOGY
- Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease
- (2014) Liang Zhou et al. MOLECULAR NEUROBIOLOGY
- Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52
- (2014) Chulman Jo et al. Nature Communications
- LC3 and p62 as Diagnostic Markers of Drug-induced Autophagic Vacuolar Cardiomyopathy
- (2013) Brianne H. Daniels et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Food restriction-induced autophagy modulates degradation of mutant SOD1 in an amyotrophic lateral sclerosis mouse model
- (2013) Kunxi Zhang et al. BRAIN RESEARCH
- Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy
- (2013) Jae Myung Park et al. CANCER BIOLOGY & THERAPY
- Prognostic Impact of p62 Expression in Cutaneous Malignant Melanoma
- (2013) Robert A. Ellis et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Deficiency of p62/Sequestosome 1 Causes Hyperphagia Due to Leptin Resistance in the Brain
- (2013) H. Harada et al. JOURNAL OF NEUROSCIENCE
- Kinetic, Thermodynamic, and Structural Characterizations of the Association between Nrf2-DLGex Degron and Keap1
- (2013) Toshiaki Fukutomi et al. MOLECULAR AND CELLULAR BIOLOGY
- K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells
- (2013) Juan F. Linares et al. MOLECULAR CELL
- Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
- (2013) Yoshinobu Ichimura et al. MOLECULAR CELL
- Autophagy proteins in prostate cancer: Relation with anaerobic metabolism and Gleason score11The study was financially supported by the Tumor and Angiogenesis Research Group.
- (2013) Alexandra Giatromanolaki et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Mixed tau, TDP-43 and p62 pathology in FTLD associated with a C9ORF72 repeat expansion and p.Ala239Thr MAPT (tau) variant
- (2012) Andrew King et al. ACTA NEUROPATHOLOGICA
- The MAPK1/3 pathway is essential for the deregulation of autophagy observed in G2019S LRRK2 mutant fibroblasts
- (2012) José M. Bravo-San Pedro et al. Autophagy
- A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity
- (2012) M. Lamar Seibenhener et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Pathogenesis of Paget Disease of Bone
- (2012) Stuart H. Ralston et al. CALCIFIED TISSUE INTERNATIONAL
- KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma
- (2012) Jianhua Ling et al. CANCER CELL
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma
- (2012) Daisuke Inoue et al. CANCER SCIENCE
- TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
- (2012) Manohar Pilli et al. IMMUNITY
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation
- (2012) A. Aichem et al. JOURNAL OF CELL SCIENCE
- p62 Links β-adrenergic input to mitochondrial function and thermogenesis
- (2012) Timo D. Müller et al. JOURNAL OF CLINICAL INVESTIGATION
- Keap1 degradation by autophagy for the maintenance of redox homeostasis
- (2012) K. Taguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1
- (2011) Steingrim Svenning et al. Autophagy
- Contributions of the Measles Virus Nucleocapsid Gene and the SQSTM1/p62P392L Mutation to Paget's Disease
- (2011) Noriyoshi Kurihara et al. Cell Metabolism
- Autophagy-deficient mice develop multiple liver tumors
- (2011) A. Takamura et al. GENES & DEVELOPMENT
- IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux
- (2011) Huikyong Lee et al. HUMAN MOLECULAR GENETICS
- Crystal Structure of the Ubiquitin-associated (UBA) Domain of p62 and Its Interaction with Ubiquitin
- (2011) Shin Isogai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
- (2011) Yoshihiro Inami et al. JOURNAL OF CELL BIOLOGY
- p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway
- (2011) Angeles Duran et al. MOLECULAR CELL
- Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
- (2011) Gen Matsumoto et al. MOLECULAR CELL
- An MND/ALS phenotype associated withC9orf72repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline
- (2011) Claire Troakes et al. NEUROPATHOLOGY
- p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
- (2010) Terje Høyvarde Clausen et al. Autophagy
- Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
- (2010) Weiliang Fan et al. Autophagy
- p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
- (2010) Derek Narendra et al. Autophagy
- Protein misfolding disorders and macroautophagy
- (2010) Fiona M Menzies et al. CURRENT OPINION IN CELL BIOLOGY
- A functional role for the p62–ERK1 axis in the control of energy homeostasis and adipogenesis
- (2010) Sang Jun Lee et al. EMBO REPORTS
- p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
- (2010) Kei Okatsu et al. GENES TO CELLS
- p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation
- (2010) J. F. Linares et al. MOLECULAR AND CELLULAR BIOLOGY
- A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
- (2010) A. Lau et al. MOLECULAR AND CELLULAR BIOLOGY
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Selective degradation of p62 by autophagy
- (2010) Yoshinobu Ichimura et al. Seminars in Immunopathology
- NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets
- (2009) Vladimir Kirkin et al. Autophagy
- Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
- (2009) Zhaoyu Jin et al. CELL
- Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies
- (2009) Serhiy Pankiv et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling
- (2009) Jed Long et al. JOURNAL OF MOLECULAR BIOLOGY
- Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
- (2009) Jozsef Gal et al. JOURNAL OF NEUROCHEMISTRY
- Oxidative damage to the promoter region of SQSTM1/p62 is common to neurodegenerative disease
- (2009) Yifeng Du et al. NEUROBIOLOGY OF DISEASE
- The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
- (2008) Angeles Duran et al. CANCER CELL
- Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease
- (2008) Yifeng Du et al. FREE RADICAL BIOLOGY AND MEDICINE
- Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
- (2008) Yoshinobu Ichimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice
- (2008) Wei Jin et al. JOURNAL OF CLINICAL INVESTIGATION
- Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
- (2008) J. Ramesh Babu et al. JOURNAL OF NEUROCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now