Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition

p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer

(2016) Angeles Duran et al.   CANCER CELL

AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27

(2016) Stavros Kopsiaftis et al.   MOLECULAR CANCER RESEARCH

SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer

(2016) W Lu et al.   ONCOGENE

Skp2 Regulates the Expression of MMP-2 and MMP-9, and Enhances the Invasion Potential of Oral Squamous Cell Carcinoma

(2016) Shin-ichi Yamada et al.   PATHOLOGY & ONCOLOGY RESEARCH

The Role of PB1 Domain Proteins in Endothelial Cell Dysfunction and Disease

(2015) Ryan M. Burke et al.   ANTIOXIDANTS & REDOX SIGNALING

Cytoplasmic Accumulation of Sequestosome 1 (p62) Is a Predictor of Biochemical Recurrence, Rapid Tumor Cell Proliferation, and Genomic Instability in Prostate Cancer

(2015) C. Burdelski et al.   CLINICAL CANCER RESEARCH

Acid-induced autophagy protects human lung cancer cells from apoptosis by activating ER stress

(2015) Wen-Yue Xie et al.   EXPERIMENTAL CELL RESEARCH

P62/Ubiquitin IHC Expression Correlated with Clinicopathologic Parameters and Outcome in Gastrointestinal Carcinomas

(2015) Amr Mohamed et al.   Frontiers in Oncology

G226, a novel epipolythiodioxopiperazine derivative, induces autophagy and caspase-dependent apoptosis in human breast cancer cells in vitro

(2014) Peng-xing He et al.   ACTA PHARMACOLOGICA SINICA

Epidermal Growth Factor Receptor Inhibition Slows Progression of Diabetic Nephropathy in Association With a Decrease in Endoplasmic Reticulum Stress and an Increase in Autophagy

(2014) Ming-Zhi Zhang et al.   DIABETES

Phase I dose escalation study of the PKCι inhibitor aurothiomalate for advanced non-small-cell lung cancer, ovarian cancer, and pancreatic cancer

(2013) Aaron S. Mansfield et al.   ANTI-CANCER DRUGS

Effects of aurothiomalate treatment on canine osteosarcoma in a murine xenograft model

(2013) Valery F. Scharf et al.   ANTI-CANCER DRUGS

SQSTM1 Is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer

(2013) Lianjie Li et al.   CANCER CELL

Oesophageal carcinoma

(2013) Arjun Pennathur et al.   LANCET

Inhibition of atypical protein kinase Cι induces apoptosis through autophagic degradation of β-catenin in esophageal cancer cells

(2013) Bo-Shi Wang et al.   MOLECULAR CARCINOGENESIS

Association of p62/SQSTM1 Excess and Oral Carcinogenesis

(2013) Takuma Inui et al.   PLoS One

Structural and biochemical insights into the homotypic PB1-PB1 complex between PKCζ and p62

(2013) Jun Ren et al.   Science China-Life Sciences

Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma

(2012) Daisuke Inoue et al.   CANCER SCIENCE

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

(2010) Terje Høyvarde Clausen et al.   Autophagy

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies

(2009) Serhiy Pankiv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

(2009) Kazuhiro Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Anoikis bySKP2Amplification and Overexpression Promotes Metastasis of Esophageal Squamous Cell Carcinoma

(2009) Xiao-Chun Wang et al.   MOLECULAR CANCER RESEARCH