Distinct roles for motor neuron autophagy early and late in the SOD1G93Amouse model of ALS
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Distinct roles for motor neuron autophagy early and late in the SOD1G93Amouse model of ALS
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 39, Pages E8294-E8303
Publisher
Proceedings of the National Academy of Sciences
Online
2017-09-14
DOI
10.1073/pnas.1704294114
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy
- (2016) Christopher P Webster et al. EMBO JOURNAL
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- Human TBK1: A Gatekeeper of Neuroinflammation
- (2016) Liyana Ahmad et al. TRENDS IN MOLECULAR MEDICINE
- Common Molecular Pathways in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
- (2016) Jochen H. Weishaupt et al. TRENDS IN MOLECULAR MEDICINE
- The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway
- (2016) Peter M. Sullivan et al. Acta Neuropathologica Communications
- Endolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice
- (2015) Yuxiang Xie et al. NEURON
- Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model
- (2015) Y. Li et al. NEUROSCIENCE
- Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS
- (2015) Shuying Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
- (2015) E. T. Cirulli et al. SCIENCE
- Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis
- (2014) Melissa Nassif et al. Autophagy
- MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis
- (2014) Xiaojie Zhang et al. Autophagy
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
- (2014) Vladimir Rogov et al. MOLECULAR CELL
- Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
- (2014) Jing L Guo et al. NATURE MEDICINE
- Nuclear and cytosolic JNK signalling in neurons
- (2014) Eleanor T. Coffey NATURE REVIEWS NEUROSCIENCE
- Neuronal Matrix Metalloproteinase-9 Is a Determinant of Selective Neurodegeneration
- (2014) Artem Kaplan et al. NEURON
- Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits
- (2014) Guomei Tang et al. NEURON
- Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
- (2014) Francesc Baixauli et al. Frontiers in Immunology
- Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
- (2013) Karen Castillo et al. Autophagy
- Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion
- (2013) Patrick Ejlerskov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Amyotrophic lateral sclerosis—a model of corticofugal axonal spread
- (2013) Heiko Braak et al. Nature Reviews Neurology
- RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse
- (2013) Urmi Bandyopadhyay et al. PLoS One
- Specific Distribution of the Autophagic Protein GABARAPL1/GEC1 in the Developing and Adult Mouse Brain and Identification of Neuronal Populations Expressing GABARAPL1/GEC1
- (2013) Jaclyn Nicole Le Grand et al. PLoS One
- Intricate interplay between astrocytes and motor neurons in ALS
- (2013) H. P. Phatnani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aβ Secretion and Plaque Formation Depend on Autophagy
- (2013) Per Nilsson et al. Cell Reports
- A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
- (2013) Isaac M. Chiu et al. Cell Reports
- Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway
- (2013) Keiichi Inoue et al. PLoS Genetics
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Motor Neuron-specific Disruption of Proteasomes, but Not Autophagy, Replicates Amyotrophic Lateral Sclerosis
- (2012) Yoshitaka Tashiro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
- (2012) Sandra Maday et al. JOURNAL OF CELL BIOLOGY
- Alterations in the motor neuron-renshaw cell circuit in theSod1G93Amouse model
- (2012) Hanna Wootz et al. JOURNAL OF COMPARATIVE NEUROLOGY
- High-contrast en bloc staining of neuronal tissue for field emission scanning electron microscopy
- (2012) Juan Carlos Tapia et al. Nature Protocols
- Regulation of Presynaptic Neurotransmission by Macroautophagy
- (2012) Daniela Hernandez et al. NEURON
- The Role of Atg Proteins in Autophagosome Formation
- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- Rapamycin treatment augments motor neuron degeneration in SOD1G93Amouse model of amyotrophic lateral sclerosis
- (2011) Xiaojie Zhang et al. Autophagy
- Spinal Inhibitory Interneuron Pathology Follows Motor Neuron Degeneration Independent of Glial Mutant Superoxide Dismutase 1 Expression in SOD1-ALS Mice
- (2011) Mehdi Hossaini et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data
- (2011) Brad A Friedman et al. GENOME BIOLOGY
- Motor Neuron Diversity in Development and Disease
- (2010) Kevin C. Kanning et al. Annual Review of Neuroscience
- Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice
- (2009) Chiara Pizzasegola et al. Amyotrophic Lateral Sclerosis
- Autophagy promotes synapse development inDrosophila
- (2009) Wei Shen et al. JOURNAL OF CELL BIOLOGY
- Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
- (2009) Jozsef Gal et al. JOURNAL OF NEUROCHEMISTRY
- Renshaw Cell Recurrent Inhibition Improves Physiological Tremor by Reducing Corticomuscular Coupling at 10 Hz
- (2009) E. R. Williams et al. JOURNAL OF NEUROSCIENCE
- ALS motor phenotype heterogeneity, focality, and spread: Deconstructing motor neuron degeneration
- (2009) J. M. Ravits et al. NEUROLOGY
- A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity
- (2009) Laskaro Zagoraiou et al. NEURON
- No Benefit from Chronic Lithium Dosing in a Sibling-Matched, Gender Balanced, Investigator-Blinded Trial Using a Standard Mouse Model of Familial ALS
- (2009) Alan Gill et al. PLoS One
- A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
- (2008) J. D. Cahoy et al. JOURNAL OF NEUROSCIENCE
- Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
- (2008) Koji Yamanaka et al. NATURE NEUROSCIENCE
- Lithium delays progression of amyotrophic lateral sclerosis
- (2008) F. Fornai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started