Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells

PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE Exposure

(2015) H. Huang et al.   CLINICAL CANCER RESEARCH

A Novel Post-translational Modification of Nucleolin, SUMOylation at Lys-294, Mediates Arsenite-induced Cell Death by Regulatinggadd45α mRNA Stability

(2015) Dongyun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability

(2015) Guangxun Gao et al.   Oncotarget

NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression

(2015) Haishan Huang et al.   Oncotarget

Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells

(2015) Jingjie Zhang et al.   Oncotarget

Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation

(2014) J. Zhu et al.   Cancer Prevention Research

p62/SQSTM1 synergizes with autophagy for tumor growth in vivo

(2014) H. Wei et al.   GENES & DEVELOPMENT

Axonal protection by modulation of p62 expression in TNF-induced optic nerve degeneration

(2014) Kaori Kojima et al.   NEUROSCIENCE LETTERS

Current Perspective on the Global and United States Cancer Burden Attributable to Lifestyle and Environmental Risk Factors

(2013) David Schottenfeld et al.   Annual Review of Public Health

p27 suppresses cyclooxygenase-2 expression by inhibiting p38β and p38δ-mediated CREB phosphorylation upon arsenite exposure

(2013) Xun Che et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chronic inflammation and cancer: suppressing the suppressors

(2013) Michal Baniyash et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Lung Cancer in China

(2013) Jun She et al.   CHEST

Knockdown of p62/sequestosome 1 attenuates autophagy and inhibits colorectal cancer cell growth

(2013) Feng Ren et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Arsenic Inhibits Autophagic Flux, Activating the Nrf2-Keap1 Pathway in a p62-Dependent Manner

(2013) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

p62/SQSTM1 Enhances NOD2-Mediated Signaling and Cytokine Production through Stabilizing NOD2 Oligomerization

(2013) Sangwook Park et al.   PLoS One

Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells

(2013) Johanna Viiri et al.   PLoS One

Autophagy is a protective response to ethanol neurotoxicity

(2012) Gang Chen et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Hypoxia, MTOR and autophagy

(2012) Mikhail V. Blagosklonny   Autophagy

Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma

(2012) Daisuke Inoue et al.   CANCER SCIENCE

Hexavalent Chromium Cr(VI) Up-Regulates COX-2 Expression through an NFκB/c-Jun/AP-1–Dependent Pathway

(2012) Zhenghong Zuo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The Chinese Herb Isolate Isorhapontigenin Induces Apoptosis in Human Cancer Cells by Down-regulating Overexpression of Antiapoptotic Protein XIAP

(2012) Yong Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative pulmonary toxicity of inhaled nickel nanoparticles; role of deposited dose and solubility

(2011) Gi Soo Kang et al.   INHALATION TOXICOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Loss of Cytoplasmic CDK1 Predicts Poor Survival in Human Lung Cancer and Confers Chemotherapeutic Resistance

(2011) Chunyu Zhang et al.   PLoS One

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK1 Mediates Degradation HIF-1  by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70

(2010) D. Zhang et al.   CANCER RESEARCH

Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: Short and long-term studies in mice

(2010) Patricia A. Gillespie et al.   Nanotoxicology

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

TNF-α Induction by Nickel Compounds is Specific Through ERKs/AP-1- Dependent Pathway in Human Bronchial Epithelial Cells

(2009) Jin Ding et al.   CURRENT CANCER DRUG TARGETS

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Current concepts on the role of inflammation in COPD and lung cancer

(2009) Hongwei Yao et al.   CURRENT OPINION IN PHARMACOLOGY

Enhanced neointimal hyperplasia and carotid artery remodelling in sequestosome 1 deficient mice

(2009) Rika Sugimoto et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oxidative damage to the promoter region of SQSTM1/p62 is common to neurodegenerative disease

(2009) Yifeng Du et al.   NEUROBIOLOGY OF DISEASE

The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis

(2008) Angeles Duran et al.   CANCER CELL

Yin-Yang Activities and Vicious Cycles in the Tumor Microenvironment

(2008) I. P. Witz   CANCER RESEARCH

c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells

(2008) Dongyun Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Tristetraprolin regulates TNF TNF-α mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways

(2007) Kristen M. Deleault et al.   MOLECULAR IMMUNOLOGY