Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer’s disease

Early striatal amyloid deposition distinguishes Down syndrome and autosomal dominant Alzheimer's disease from late-onset amyloid deposition

(2018) Ann D. Cohen et al.   Alzheimers & Dementia

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Person-specific contribution of neuropathologies to cognitive loss in old age

(2018) Patricia A. Boyle et al.   ANNALS OF NEUROLOGY

Effects of amyloid pathology and neurodegeneration on cognitive change in cognitively normal adults

(2018) Murat Bilgel et al.   BRAIN

Longitudinal tau PET in ageing and Alzheimer’s disease

(2018) Clifford R Jack et al.   BRAIN

OUP accepted manuscript

(2018)   BRAIN

Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach

(2018) Erika Bereczki et al.   BRAIN

Higher exosomal phosphorylated tau and total tau among veterans with combat-related repetitive chronic mild traumatic brain injury

(2018) Kimbra Kenney et al.   BRAIN INJURY

Fluid and imaging biomarkers for Alzheimer's disease: Where we stand and where to head to

(2018) Adriane Dallanora Henriques et al.   EXPERIMENTAL GERONTOLOGY

Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses

(2018) Anatoliy I. Yashin et al.   EXPERIMENTAL GERONTOLOGY

Alzheimer’s Amyloid-β is an Antimicrobial Peptide: A Review of the Evidence

(2018) Maya L. Gosztyla et al.   JOURNAL OF ALZHEIMERS DISEASE

The Vascular Hypothesis of Alzheimer’s Disease: A Key to Preclinical Prediction of Dementia Using Neuroimaging

(2018) Jack de la Torre   JOURNAL OF ALZHEIMERS DISEASE

A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients

(2018) Diana Furcila et al.   JOURNAL OF ALZHEIMERS DISEASE

From Subjective Cognitive Decline to Alzheimer’s Disease: The Predictive Role of Neuropsychological Assessment, Personality Traits, and Cognitive Reserve. A 7-Year Follow-Up Study

(2018) Valentina Bessi et al.   JOURNAL OF ALZHEIMERS DISEASE

Herpes Viruses and Senile Dementia: First Population Evidence for a Causal Link

(2018) Ruth F. Itzhaki et al.   JOURNAL OF ALZHEIMERS DISEASE

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

(2018) Brian A Gordon et al.   LANCET NEUROLOGY

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions

(2018) Victor L. Villemagne et al.   Nature Reviews Neurology

Memory decline accompanies subthreshold amyloid accumulation

(2018) Susan M. Landau et al.   NEUROLOGY

TREM2 and Amyloid Beta: A Love-Hate Relationship

(2018) Joe Udeochu et al.   NEURON

Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

(2018) Ben Readhead et al.   NEURON

Anti-herpetic Medications and Reduced Risk of Dementia in Patients with Herpes Simplex Virus Infections—a Nationwide, Population-Based Cohort Study in Taiwan

(2018) Nian-Sheng Tzeng et al.   Neurotherapeutics

Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease

(2018) Michael F. Egan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease

(2018) Lawrence S. Honig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Understanding Alzheimer Disease at the Interface between Genetics and Transcriptomics

(2018) Jan Verheijen et al.   TRENDS IN GENETICS

Cognition comes of age: comments on the new FDA draft guidance for early Alzheimer’s disease

(2018) John E. Harrison   Alzheimers Research & Therapy

The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

(2018) Holly M. Brothers et al.   Frontiers in Aging Neuroscience

Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease

(2018) Yakeel T. Quiroz et al.   JAMA Neurology

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

(2018) Ming-Kai Chen et al.   JAMA Neurology

Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort

(2018) Arno de Wilde et al.   JAMA Neurology

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

(2018) Willemijn J. Jansen et al.   JAMA Psychiatry

Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

(2018) Leonardo Iaccarino et al.   NeuroImage-Clinical

Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease

(2018) Neha S. Raghavan et al.   Annals of Clinical and Translational Neurology

Therapeutic implications of how TNF links apolipoprotein E, phosphorylated tau, α-synuclein, amyloid-β and insulin resistance in neurodegenerative diseases

(2018) I A Clark et al.   BRITISH JOURNAL OF PHARMACOLOGY

“End-Stage” Neurofibrillary Tangle Pathology in Preclinical Alzheimer's Disease: Fact or Fiction?

(2018) Erin L. Abner et al.   JOURNAL OF ALZHEIMERS DISEASE

Injury Markers but not Amyloid Markers are Associated with Rapid Progression from Mild Cognitive Impairment to Dementia in Alzheimer's Disease

(2018) Ineke A. van Rossum et al.   JOURNAL OF ALZHEIMERS DISEASE

Clinical Symptoms and Symptom Signatures of Alzheimer's Disease Subgroups

(2018) Khalid Iqbal et al.   JOURNAL OF ALZHEIMERS DISEASE

Detecting Early Preclinical Alzheimer's Disease via Cognition, Neuropsychiatry, and Neuroimaging: Qualitative Review and Recommendations for Testing

(2018) Sylvie Belleville et al.   JOURNAL OF ALZHEIMERS DISEASE

Structures of filaments from Pick’s disease reveal a novel tau protein fold

(2018) Benjamin Falcon et al.   NATURE

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

(2018) Eric McDade et al.   NEUROLOGY

The discovery of Alzheimer-causing mutations in the APP gene and the formulation of the “amyloid cascade hypothesis”

(2017) John Hardy   FEBS Journal

Alzheimer’s Disease: Characterization of the Brain Sites of the Initial Tau Cytoskeletal Pathology Will Improve the Success of Novel Immunological Anti-Tau Treatment Approaches

(2017) Udo Rüb et al.   JOURNAL OF ALZHEIMERS DISEASE

Re-imagining Alzheimer's disease - the diminishing importance of amyloid and a glimpse of what lies ahead

(2017) Kai-Hei Tse et al.   JOURNAL OF NEUROCHEMISTRY

Beyond Amyloid - Widening the View on Alzheimer's Disease

(2017) Christian Behl et al.   JOURNAL OF NEUROCHEMISTRY

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice

(2017) Gargi Banerjee et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Dementia After Moderate-Severe Traumatic Brain Injury: Coexistence of Multiple Proteinopathies

(2017) Kimbra Kenney et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Dementia prevention, intervention, and care

(2017) Gill Livingston et al.   LANCET

Alzheimer Disease

(2017) Richard J. Caselli et al.   MAYO CLINIC PROCEEDINGS

Longitudinal changes of tau PET imaging in relation to hypometabolism in prodromal and Alzheimer’s disease dementia

(2017) K Chiotis et al.   MOLECULAR PSYCHIATRY

Study partners should be required in preclinical Alzheimer’s disease trials

(2017) Joshua D. Grill et al.   Alzheimers Research & Therapy

β-Amyloid Prions and the Pathobiology of Alzheimer’s Disease

(2017) Joel C. Watts et al.   Cold Spring Harbor Perspectives in Medicine

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

(2017) Rahul S. Desikan et al.   PLOS MEDICINE

APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases

(2017) Hélène-Marie Lanoiselée et al.   PLOS MEDICINE

Association of Longitudinal Cognitive Decline With Amyloid Burden in Middle-aged and Older Adults

(2017) Michelle E. Farrell et al.   JAMA Neurology

Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα

(2017) Bruce G. Mockett et al.   Frontiers in Molecular Neuroscience

Neuropathologic Studies of the Baltimore Longitudinal Study of Aging (BLSA)

(2017) Richard J. O'Brien et al.   JOURNAL OF ALZHEIMERS DISEASE

A Physiological Role for Amyloid-β Protein: Enhancement of Learning and Memory

(2017) John E. Morley et al.   JOURNAL OF ALZHEIMERS DISEASE

Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging

(2017) Allissa A. Dillman et al.   Scientific Reports

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

(2016) Bruno Vasconcelos et al.   ACTA NEUROPATHOLOGICA

Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease

(2016) Olav M. Andersen et al.   ACTA NEUROPATHOLOGICA

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

(2016) Bruno Dubois et al.   Alzheimers & Dementia

Beta-amyloid and cognitive decline in late middle age: Findings from the Wisconsin Registry for Alzheimer's Prevention study

(2016) Lindsay R. Clark et al.   Alzheimers & Dementia

Molecular genetics of early-onset Alzheimer's disease revisited

(2016) Rita Cacace et al.   Alzheimers & Dementia

Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability

(2016) Martijn C. de Wilde et al.   Alzheimers & Dementia

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Microbes and Alzheimer’s Disease

(2016) Ruth F. Itzhaki et al.   JOURNAL OF ALZHEIMERS DISEASE

The amyloid cascade hypothesis: are we poised for success or failure?

(2016) Eric Karran et al.   JOURNAL OF NEUROCHEMISTRY

Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents

(2016) Ian A. Clark et al.   Journal of Neuroinflammation

“New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)

(2016) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression

(2016) T. Saito et al.   JOURNAL OF NEUROSCIENCE

A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences

(2016) Yat-Fung Shea et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial

(2016) Serge Gauthier et al.   LANCET

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study

(2016) Panagiotis Fotiadis et al.   LANCET NEUROLOGY

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

(2016) Bob Olsson et al.   LANCET NEUROLOGY

Suspected non-Alzheimer disease pathophysiology — concept and controversy

(2016) Clifford R. Jack et al.   Nature Reviews Neurology

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

(2016) Clifford R. Jack et al.   NEUROLOGY

Amyloid pathology and axonal injury after brain trauma

(2016) Gregory Scott et al.   NEUROLOGY

Relation of genomic variants for Alzheimer disease dementia to common neuropathologies

(2016) Jose M. Farfel et al.   NEUROLOGY

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase

(2016) Linfeng Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Alzheimer’s Disease Assessment Scale–Cognitive subscale variants in mild cognitive impairment and mild Alzheimer’s disease: change over time and the effect of enrichment strategies

(2016) Jana Podhorna et al.   Alzheimers Research & Therapy

Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease

(2016) Gregory S. Day et al.   JAMA Neurology

Heterogeneity in Suspected Non–Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals

(2016) Elizabeth C. Mormino et al.   JAMA Neurology

Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression

(2016) Henrik Zetterberg et al.   JAMA Neurology

Genes associated with Alzheimer's disease: an overview and current status

(2016) Mohan Giri et al.   Clinical Interventions in Aging

Helicobacter Pylori: A Nobel Pursuit?

(2016) Barry Marshall et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

(2015) Hlin Kvartsberg et al.   Alzheimers & Dementia

Emerging Concepts in Alzheimer's Disease

(2015) Harry V. Vinters   Annual Review of Pathology-Mechanisms of Disease

Alzheimer’s disease in the 100 years since Alzheimer’s death

(2015) Natalie S. Ryan et al.   BRAIN

Is amyloid-β harmful to the brain? Insights from human imaging studies

(2015) William Jagust   BRAIN

Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology

(2015) Katharina Stratmann et al.   BRAIN PATHOLOGY

Amyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's disease

(2015) I A Clark et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer's Disease

(2015) Huntington Potter et al.   Current Alzheimer Research

Herding, social influences and behavioural bias in scientific research: Simple awareness of the hidden pressures and beliefs that influence our thinking can help to preserve objectivity

(2015) M. Baddeley   EMBO REPORTS

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Prevalence of Amyloid PET Positivity in Dementia Syndromes

(2015) Rik Ossenkoppele et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia

(2015) Willemijn J. Jansen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Differentiated clinical presentation of early and late-onset Alzheimer’s disease: is 65 years of age providing a reliable threshold?

(2015) Antonio Palasí et al.   JOURNAL OF NEUROLOGY

Amyloid deposition in Parkinson's disease and cognitive impairment: A systematic review

(2015) Myria Petrou et al.   MOVEMENT DISORDERS

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

Cognitive impairment 18 years before clinical diagnosis of Alzheimer disease dementia

(2015) Kumar B. Rajan et al.   NEUROLOGY

Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons

(2015) Patricia A. Boyle et al.   NEUROLOGY

Hippocampal plasticity during the progression of Alzheimer’s disease

(2015) E.J. Mufson et al.   NEUROSCIENCE

The keystone of Alzheimer pathogenesis might be sought in Aβ physiology

(2015) D. Puzzo et al.   NEUROSCIENCE

SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer´s disease: appealing for ESI-IM-MS

(2015) Rosa Pujol-Pina et al.   Scientific Reports

Early astrocytosis in autosomal dominant Alzheimer’s disease measured in vivo by multi-tracer positron emission tomography

(2015) Michael Schöll et al.   Scientific Reports

Cerebrospinal fluid VILIP-1 and YKL-40, candidate biomarkers to diagnose, predict and monitor Alzheimer’s disease in a memory clinic cohort

(2015) Maartje I. Kester et al.   Alzheimers Research & Therapy

Historic evidence to support a causal relationship between spirochetal infections and Alzheimer’s disease

(2015) Judith Miklossy   Frontiers in Aging Neuroscience

Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease

(2015) Maartje I. Kester et al.   JAMA Neurology

Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred

(2015) Adam S. Fleisher et al.   JAMA Neurology

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

(2015) Amy M Pooler et al.   Acta Neuropathologica Communications

Different Brain Regions are Infected with Fungi in Alzheimer’s Disease

(2015) Diana Pisa et al.   Scientific Reports

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Mild to moderate Alzheimer dementia with insufficient neuropathological changes

(2014) Alberto Serrano-Pozo et al.   ANNALS OF NEUROLOGY

The complexities of the pathology–pathogenesis relationship in Alzheimer disease

(2014) Rudy J. Castellani et al.   BIOCHEMICAL PHARMACOLOGY

Is synaptic loss a unique hallmark of Alzheimer's disease?

(2014) Stephen W. Scheff et al.   BIOCHEMICAL PHARMACOLOGY

Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer’s disease

(2014) Michael A Castello et al.   BMC Neurology

The dark sides of amyloid in Alzheimer's disease pathogenesis

(2014) Pierpaolo Sorrentino et al.   FEBS LETTERS

Quantifying the quiet epidemic

(2014) Duncan Wilson   HISTORY OF THE HUMAN SCIENCES

Advances in the prevention of Alzheimer's disease and dementia

(2014) A. Solomon et al.   JOURNAL OF INTERNAL MEDICINE

Mild Cognitive Impairment and Asymptomatic Alzheimer Disease Subjects

(2014) Diego Iacono et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

The Role of SORL1 in Alzheimer’s Disease

(2014) Rui-Hua Yin et al.   MOLECULAR NEUROBIOLOGY

SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease

(2014) Ann Brinkmalm et al.   Molecular Neurodegeneration

The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials

(2014) Reisa Sperling et al.   NEURON

ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

(2014) Takahisa Kanekiyo et al.   NEURON

Unbiased Approaches to Biomarker Discovery in Neurodegenerative Diseases

(2014) Alice S. Chen-Plotkin   NEURON

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease

(2014) A. M. Fagan et al.   Science Translational Medicine

Amyloid Burden, Neuroinflammation, and Links to Cognitive Decline After Ischemic Stroke

(2014) Alexander Thiel et al.   STROKE

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

(2014) Gary W. Beecham et al.   PLoS Genetics

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples

(2013) Andrew D. Watt et al.   ACTA NEUROPATHOLOGICA

Much of late life cognitive decline is not due to common neurodegenerative pathologies

(2013) Patricia A. Boyle et al.   ANNALS OF NEUROLOGY

Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus

(2013) Margaret M Ryan et al.   BMC GENOMICS

Dissecting phenotypic traits linked to human resilience to Alzheimer’s pathology

(2013) Beatriz G. Perez-Nievas et al.   BRAIN

Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles

(2013) C. H. Andrade-Moraes et al.   BRAIN

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

The Nun Study: Risk Factors for Pathology and Clinical-Pathologic Correlations

(2013) James A. Mortimer   Current Alzheimer Research

Overview and Findings from the Religious Orders Study

(2013) David A. Bennett et al.   Current Alzheimer Research

Confluence of α-Synuclein, Tau, and β-Amyloid Pathologies in Dementia With Lewy Bodies

(2013) Martí Colom-Cadena et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Aβ-independent processes—rethinking preclinical AD

(2013) Gaël Chételat   Nature Reviews Neurology

Alzheimer disease therapy—moving from amyloid-β to tau

(2013) Ezio Giacobini et al.   Nature Reviews Neurology

Microglia: A new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research

(2013) Gary P. Morris et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later

(2013) C. M. Roe et al.   NEUROLOGY

Brain  -amyloid load approaches a plateau

(2013) C. R. Jack et al.   NEUROLOGY

A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease

(2013) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

(2013) T. L. S. Benzinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the subject of rigor in the study of amyloid β-protein assembly

(2013) David B Teplow   Alzheimers Research & Therapy

Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

(2013) Benjamin Lam et al.   Alzheimers Research & Therapy

Genetic Susceptibility for Alzheimer Disease Neuritic Plaque Pathology

(2013) Joshua M. Shulman et al.   JAMA Neurology

Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease

(2013) Gaël Chételat et al.   NeuroImage-Clinical

The airbag problem–a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer’s disease

(2013) Dimitrije Krstic et al.   Acta Neuropathologica Communications

Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease

(2012) Marta Pera et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Putting the Alzheimer's cognitive test to the test II: Rasch Measurement Theory

(2012) Jeremy Hobart et al.   Alzheimers & Dementia

Amyloid deposition, hypometabolism, and longitudinal cognitive decline

(2012) Susan M. Landau et al.   ANNALS OF NEUROLOGY

Brain injury biomarkers are not dependent on β-amyloid in normal elderly

(2012) David S. Knopman et al.   ANNALS OF NEUROLOGY

Subjective Cognition and Amyloid Deposition Imaging

(2012) Audrey Perrotin   ARCHIVES OF NEUROLOGY

Alzheimer's therapeutics: Continued clinical failures question the validity of the amyloid hypothesis—but what lies beyond?

(2012) Kevin Mullane et al.   BIOCHEMICAL PHARMACOLOGY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010

(2012) Thomas G. Beach et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

(2012) Rebecca E. Amariglio et al.   NEUROPSYCHOLOGIA

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of Brief Cognitive Tests and CSF Biomarkers in Predicting Alzheimer’s Disease in Mild Cognitive Impairment: Six-Year Follow-Up Study

(2012) Sebastian Palmqvist et al.   PLoS One

Alzheimer’s disease is not “brain aging”: neuropathological, genetic, and epidemiological human studies

(2011) Peter T. Nelson et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Revised criteria for diagnosis of Alzheimer’s disease: National Institute on Aging-Alzheimer's Association diagnostic guidelines for Alzheimer's disease

(2011) Zaven S. Khachaturian   Alzheimers & Dementia

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

(2011) Victor L. Villemagne et al.   ANNALS OF NEUROLOGY

Longitudinal Change of Biomarkers in Cognitive Decline

(2011) Raymond Y. Lo   ARCHIVES OF NEUROLOGY

Evidence for Ordering of Alzheimer Disease Biomarkers

(2011) Clifford R. Jack   ARCHIVES OF NEUROLOGY

Autosomal Recessive Causes Likely in Early-Onset Alzheimer Disease

(2011) Thomas S. Wingo   ARCHIVES OF NEUROLOGY

The amyloid cascade hypothesis has misled the pharmaceutical industry

(2011)   BIOCHEMICAL SOCIETY TRANSACTIONS

Cerebrovascular lesions induce transient  -amyloid deposition

(2011) M. Garcia-Alloza et al.   BRAIN

Are Tangles as Toxic as They Look?

(2011) Tara L. Spires-Jones et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Alzheimer Disease Pathology in Subjects Without Dementia in 2 Studies of Aging: The Nun Study and the Adult Changes in Thought Study

(2011) Karen S. SantaCruz et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is ‘too big to fail’

(2011) Rudy J Castellani et al.   JOURNAL OF PATHOLOGY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Increased tau phosphorylation and beta amyloid in the hipocampus of mouse pups by early life lead exposure

(2010) N. Li et al.   ACTA BIOLOGICA HUNGARICA

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

Correlating familial Alzheimer’s disease gene mutations with clinical phenotype

(2010) Natalie S Ryan et al.   Biomarkers in Medicine

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

(2010) Victoria E. Johnson et al.   NATURE REVIEWS NEUROSCIENCE

Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging

(2010) Christopher C. Rowe et al.   NEUROBIOLOGY OF AGING

Are Aβ and Its Derivatives Causative Agents or Innocent Bystanders in AD?

(2010) Nikolaos K. Robakis   Neurodegenerative Diseases

Neurodegenerative basis of age-related cognitive decline

(2010) R. S. Wilson et al.   NEUROLOGY

The roles of TNF in brain dysfunction and disease

(2010) Ian A. Clark et al.   PHARMACOLOGY & THERAPEUTICS

Plasma F2-isoprostane level and cognitive function over eight years in non-demented older adults: Findings from the Health ABC Study

(2010) A.J. Fiocco et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

The neuropathology of probable Alzheimer disease and mild cognitive impairment

(2009) Julie A. Schneider et al.   ANNALS OF NEUROLOGY

Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease

(2009) Clifford R. Jack et al.   BRAIN

Amyloid beta mediates memory formation

(2009) A. Garcia-Osta et al.   LEARNING & MEMORY

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

(2009) Joseph L. Price et al.   NEUROBIOLOGY OF AGING

The Nun Study: Clinically silent AD, neuronal hypertrophy, and linguistic skills in early life

(2009) D. Iacono et al.   NEUROLOGY

Age, Neuropathology, and Dementia

(2009) George M. Savva et al.   NEW ENGLAND JOURNAL OF MEDICINE

Distinct patterns of brain activity in young carriers of the APOE- 4 allele

(2009) N. Filippini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Comorbidity of HIV-Associated Neurocognitive Disorders and Alzheimer’s Disease: A Foreseeable Medical Challenge in Post-HAART Era

(2008) Jiqing Xu et al.   Journal of Neuroimmune Pharmacology

Alzheimer Disease Pathology As a Host Response

(2008) Rudy J. Castellani et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY