Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer’s disease
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer’s disease
Authors
Keywords
Late onset Alzheimer’s disease, Amyloid cascade hypothesis, Anti-amyloid therapy, Amyloid beta, Familial Alzheimer’s disease, Solanezumab, Bapineuzumab, Cholesterol metabolism, Dementia, Neurodegeneration
Journal
BMC Neurology
Volume 14, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-09-01
DOI
10.1186/s12883-014-0169-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The amyloid hypothesis, time to move on: Amyloid is the downstream result, not cause, of Alzheimer's disease
- (2014) David A. Drachman Alzheimers & Dementia
- The role of amyloid-beta in the regulation of memory
- (2014) John E. Morley et al. BIOCHEMICAL PHARMACOLOGY
- Antiamyloid Therapy for Alzheimer's Disease — Are We on the Right Road?
- (2014) Eric Karran et al. NEW ENGLAND JOURNAL OF MEDICINE
- Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
- (2014) Stephen Salloway et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
- (2014) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid-β and Tau
- (2014) George S. Bloom JAMA Neurology
- On the origin of Alzheimer's disease. Trials and tribulations of the amyloid hypothesis
- (2013) Michael A. Castello et al. AGEING RESEARCH REVIEWS
- Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
- (2013) Jessica Freiherr et al. CNS DRUGS
- Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque
- (2013) Jason P. Holland et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Amyloid β precursor protein as a molecular target for amyloid β–induced neuronal degeneration in Alzheimer's disease
- (2013) Elena Anahi Bignante et al. NEUROBIOLOGY OF AGING
- Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity
- (2013) C. R. Jack et al. NEUROLOGY
- Rational heterodoxy: Cholesterol reformation of the amyloid doctrine
- (2012) Michael A. Castello et al. AGEING RESEARCH REVIEWS
- Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease
- (2012) Chaoyun Li et al. AGEING RESEARCH REVIEWS
- National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
- (2012) Bradley T. Hyman et al. Alzheimers & Dementia
- Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls
- (2012) Thomas J. Esparza et al. ANNALS OF NEUROLOGY
- Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis
- (2012) Reisa Sperling et al. LANCET NEUROLOGY
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Role of genes linked to sporadic Alzheimer's disease risk in the production of -amyloid peptides
- (2012) J. Bali et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: implications for early detection and therapy
- (2011) Vincent T. Marchesi FASEB JOURNAL
- Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
- (2011) Heiko Braak et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is ‘too big to fail’
- (2011) Rudy J Castellani et al. JOURNAL OF PATHOLOGY
- Modeling cholesterol metabolism by gene expression profiling in the hippocampus
- (2011) Christopher M. Valdez et al. Molecular BioSystems
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease
- (2011) S. Salloway et al. NEUROLOGY
- Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift
- (2011) Todd E. Golde et al. NEURON
- Soluble amyloid -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration
- (2011) M. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reimagining Alzheimer's Disease--An Age-Based Hypothesis
- (2010) K. Herrup JOURNAL OF NEUROSCIENCE
- Picomolar Amyloid- Positively Modulates Synaptic Plasticity and Memory in Hippocampus
- (2009) D. Puzzo et al. JOURNAL OF NEUROSCIENCE
- Amyloid beta mediates memory formation
- (2009) A. Garcia-Osta et al. LEARNING & MEMORY
- Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly
- (2008) Howard Jay Aizenstein et al. ARCHIVES OF NEUROLOGY
- Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
- (2008) Dennis J. Selkoe BEHAVIOURAL BRAIN RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now