The airbag problem–a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer’s disease

Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience

(2012) Orwa Aboud et al.   BMC Medicine

Enhanced  -secretase processing alters APP axonal transport and leads to axonal defects

(2012) E. M. Rodrigues et al.   HUMAN MOLECULAR GENETICS

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

(2012) Dimitrije Krstic et al.   Journal of Neuroinflammation

The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked by Prominent RNA Oxidation in Vulnerable Neurons

(2012) Akihiko Nunomura et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex

(2012) Li Sui et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Alzheimer disease pathology and longitudinal cognitive performance in the oldest-old with no dementia

(2012) A. B. Balasubramanian et al.   NEUROLOGY

Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology

(2012) Robert W. Mahley et al.   NEURON

APP Knockout Mice Experience Acute Mortality as the Result of Ischemia

(2012) Maya A. Koike et al.   PLoS One

Overlapping profiles of Abeta peptides in the Alzheimer's disease and pathological aging brains

(2012) Brenda D Moore et al.   Alzheimers Research & Therapy

Extended results of the Alzheimer’s disease anti-inflammatory prevention trial

(2011) John C. Breitner et al.   Alzheimers & Dementia

APP physiological and pathophysiological functions: insights from animal models

(2011) Qinxi Guo et al.   CELL RESEARCH

Cognition and Neuropathology in Aging: Multidimensional Perspectives from the Rush Religious Orders Study and Rush Memory and Aging Project

(2011) S. Negash et al.   Current Alzheimer Research

Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors

(2011) Ling Liu et al.   Journal of Neuroinflammation

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria

(2011) Judith Miklossy   Journal of Neuroinflammation

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

(2011) E Genin et al.   MOLECULAR PSYCHIATRY

Resolving controversies on the path to Alzheimer's therapeutics

(2011) Dennis J Selkoe   NATURE MEDICINE

Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging

(2011) Alexei A. Podtelezhnikov et al.   PLoS One

Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging

(2011) Chera L. Maarouf et al.   PLoS One

The origin and development of plaques and phosphorylated tau are associated with axonopathy in Alzheimer’s disease

(2011) Ai-Wu Xiao et al.   Neuroscience Bulletin

Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes

(2010) Philipp Spitzer et al.   Journal of Neuroinflammation

Regional brain atrophy and functional disconnection across Alzheimer's disease evolution

(2010) T. Gili et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Reimagining Alzheimer's Disease--An Age-Based Hypothesis

(2010) K. Herrup   JOURNAL OF NEUROSCIENCE

Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study

(2010) Patricia L. Kramer et al.   NEUROBIOLOGY OF AGING

Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease

(2010) Brian T. Gold et al.   NEUROIMAGE

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

TNF-α and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects

(2009) Angela R. Kamer et al.   JOURNAL OF NEUROIMMUNOLOGY

Relationships Between Expression of Apolipoprotein E and β-Amyloid Precursor Protein Are Altered in Proximity to Alzheimer β-Amyloid Plaques

(2009) Steven W. Barger et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease

(2009) Akihiko Nunomura et al.   NEUROBIOLOGY OF DISEASE

Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides

(2008) Gorazd B. Stokin et al.   HUMAN MOLECULAR GENETICS

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Aβ levels

(2008) Ana-María Simón et al.   NEUROBIOLOGY OF DISEASE

Protective effects of NSAIDs on the development of Alzheimer disease

(2008) Steven C. Vlad et al.   NEUROLOGY