Alzheimer’s disease is not “brain aging”: neuropathological, genetic, and epidemiological human studies

Validation of anti-aging drugs by treating age-related diseases

(2016) Mikhail V. Blagosklonny   Aging-US

Sources of variability in estimates of the prevalence of Alzheimer’s disease in the United States

(2011) Robert S. Wilson et al.   Alzheimers & Dementia

Trends in the incidence and prevalence of Alzheimer’s disease, dementia, and cognitive impairment in the United States

(2011) Walter A. Rocca et al.   Alzheimers & Dementia

Operationalizing diagnostic criteria for Alzheimer’s disease and other age-related cognitive impairment—Part 2

(2011) Sudha Seshadri et al.   Alzheimers & Dementia

Operationalizing diagnostic criteria for Alzheimer’s disease and other age-related cognitive impairment—Part 1

(2011) Richard Mayeux et al.   Alzheimers & Dementia

Counting dementia: There is no one “best” way

(2011) Lenore J. Launer   Alzheimers & Dementia

Reduction of aggregated Tau in neuronal processes but not in the cell bodies after Aβ42 immunisation in Alzheimer’s disease

(2010) Delphine Boche et al.   ACTA NEUROPATHOLOGICA

Neuropathology after active Aβ42 immunotherapy: implications for Alzheimer’s disease pathogenesis

(2010) Delphine Boche et al.   ACTA NEUROPATHOLOGICA

Prevalence of dementia disorders in the oldest-old: an autopsy study

(2010) Kurt A. Jellinger et al.   ACTA NEUROPATHOLOGICA

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

A Single Ascending Dose Study of Bapineuzumab in Patients With Alzheimer Disease

(2010) Ronald S. Black et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Genetic Variation and Neuroimaging Measures in Alzheimer Disease

(2010) Alessandro Biffi   ARCHIVES OF NEUROLOGY

Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes

(2010) Gyungah Jun   ARCHIVES OF NEUROLOGY

Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Beneficial effect of human anti-amyloid-β active immunization on neurite morphology and tau pathology

(2010) Alberto Serrano-Pozo et al.   BRAIN

Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing

(2010) D. Dolan et al.   BRAIN

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Thinking Outside the Box: Alzheimer-Type Neuropathology That Does Not Map Directly Onto Current Consensus Recommendations

(2010) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Reimagining Alzheimer's Disease--An Age-Based Hypothesis

(2010) K. Herrup   JOURNAL OF NEUROSCIENCE

Diabetes, related conditions, and dementia

(2010) José A. Luchsinger   JOURNAL OF THE NEUROLOGICAL SCIENCES

Is there pure vascular dementia in old age?

(2010) Kurt A. Jellinger et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Revising the definition of Alzheimer's disease: a new lexicon

(2010) Bruno Dubois et al.   LANCET NEUROLOGY

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Progeria syndromes and ageing: what is the connection?

(2010) Christopher R. Burtner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neurodegenerative basis of age-related cognitive decline

(2010) R. S. Wilson et al.   NEUROLOGY

Frontal lobe white matter hyperintensities and neurofibrillary pathology in the oldest old

(2010) T. M. Polvikoski et al.   NEUROLOGY

Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study

(2010) S. Ahtiluoto et al.   NEUROLOGY

Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study

(2010) T. Matsuzaki et al.   NEUROLOGY

The Genetics of Alzheimer Disease: Back to the Future

(2010) Lars Bertram et al.   NEURON

The senescence pathway in prostatic carcinogenesis

(2010) Sowmya Sharma et al.   PATHOLOGY

Systems biology of ageing and longevity

(2010) T. B. L. Kirkwood   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Clinical Spectrum of CADASIL and the Effect of Cardiovascular Risk Factors on Phenotype

(2010) Poneh Adib-Samii et al.   STROKE

Prevalence Estimates for Latent Neurodegenerative Disease

(2010) Thomas J. Montine   TOXICOLOGIC PATHOLOGY

Gender and health outcomes: The impact of healthcare systems and their financing on life expectancies of women and men

(2010) Sharon Asiskovitch   SOCIAL SCIENCE & MEDICINE

Dementia incidence continues to increase with age in the oldest old: The 90+ study

(2009) María M. Corrada et al.   ANNALS OF NEUROLOGY

Clinical correlates of cerebral white matter hyperintensities in cognitively normal older adults

(2009) L.R. Williams et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Different Patterns of Cerebral Injury in Dementia With or Without Diabetes

(2009) Joshua A. Sonnen   ARCHIVES OF NEUROLOGY

The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia

(2009) Suzanne Craft   ARCHIVES OF NEUROLOGY

Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection

(2009) Merce Pallas et al.   CURRENT NEUROVASCULAR RESEARCH

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brains With Medial Temporal Lobe Neurofibrillary Tangles But No Neuritic Amyloid Plaques Are a Diagnostic Dilemma But May Have Pathogenetic Aspects Distinct From Alzheimer Disease

(2009) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

(2009) Ann C. McKee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Comparison of 18F-FDG and PiB PET in Cognitive Impairment

(2009) V. J. Lowe et al.   JOURNAL OF NUCLEAR MEDICINE

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

(2009) Joseph L. Price et al.   NEUROBIOLOGY OF AGING

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Age, Neuropathology, and Dementia

(2009) George M. Savva et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer and aging: The molecular pathways

(2009) PierFrancesco Bassi et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Criteria for the neuropathological diagnosis of dementing disorders: routes out of the swamp?

(2008) Kurt A. Jellinger   ACTA NEUROPATHOLOGICA

The Aging Brain

(2008) Bruce A. Yankner et al.   Annual Review of Pathology-Mechanisms of Disease

Role of the Neuropathology of Alzheimer Disease in Dementia in the Oldest-Old

(2008) Vahram Haroutunian et al.   ARCHIVES OF NEUROLOGY

Human cerebral neuropathology of Type 2 diabetes mellitus

(2008) Peter T. Nelson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diet-induced metabolic disturbances as modulators of brain homeostasis

(2008) Le Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons

(2008) Peter T. Nelson et al.   BRAIN PATHOLOGY

The Sun Health Research Institute Brain Donation Program: Description and Eexperience, 1987–2007

(2008) Thomas G. Beach et al.   CELL AND TISSUE BANKING

Survival in Alzheimer’s Disease Is Shorter in Women Carrying Heterozygosity at Codon 129 of the PRNP Gene and No APOE ε4 Allele

(2008) Claudia Giannattasio et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Leukoencephalopathies associated with inborn errors of metabolism in adults

(2008) F. Sedel et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Type 2 Diabetes Mellitus and Cognitive Decline in Two Large Cohorts of Community-Dwelling Older Adults

(2008) Olivia I. Okereke et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Age and apoE associations with complex pathologic features in Alzheimer's disease

(2008) Gregory A. Jicha et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

Neurofibrillary changes of the Alzheimer type in very elderly individuals: Neither inevitable nor benign

(2008) Kelly Del Tredici et al.   NEUROBIOLOGY OF AGING

APOE-related mortality: Effect of dementia, cardiovascular disease and gender

(2008) Lina Rosvall et al.   NEUROBIOLOGY OF AGING

Vascular Disease among Hospitalized Multiple Sclerosis Patients

(2008) Norrina B. Allen et al.   NEUROEPIDEMIOLOGY

MRI correlates of neurofibrillary tangle pathology at autopsy: A voxel-based morphometry study

(2008) J. L. Whitwell et al.   NEUROLOGY

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

(2008) Peter T. Nelson et al.   NEUROSCIENCE LETTERS

Telomeres and Aging

(2008) Geraldine Aubert et al.   PHYSIOLOGICAL REVIEWS

Oxidatively modified RNA in mild cognitive impairment

(2007) Mark A. Lovell et al.   NEUROBIOLOGY OF DISEASE