The “Yin and Yang” of Natural Compounds in Anticancer Therapy of Triple-Negative Breast Cancers
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Title
The “Yin and Yang” of Natural Compounds in Anticancer Therapy of Triple-Negative Breast Cancers
Authors
Keywords
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Journal
Cancers
Volume 10, Issue 10, Pages 346
Publisher
MDPI AG
Online
2018-09-21
DOI
10.3390/cancers10100346
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Note: Only part of the references are listed.- Deguelin Impairs Cell Adhesion, Migration and Invasion of Human Lung Cancer Cells through the NF-κB Signaling Pathways
- (2018) Yung-Ting Hsiao et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Chemotherapeutic agents for the treatment of metastatic breast cancer: An update
- (2018) Mariam Abotaleb et al. BIOMEDICINE & PHARMACOTHERAPY
- A review on the chemotherapeutic potential of fisetin: In vitro evidences
- (2018) Kiruthika Sundarraj et al. BIOMEDICINE & PHARMACOTHERAPY
- Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review
- (2018) Ricardo L. B. Costa et al. BREAST CANCER RESEARCH AND TREATMENT
- Deguelin exerts anticancer activity of human gastric cancer MGC-803 and MKN-45 cells in vitro
- (2018) Wen Kang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Asparagine bioavailability governs metastasis in a model of breast cancer
- (2018) Simon R. V. Knott et al. NATURE
- PI3K-AKT-mTOR inhibition in cancer immunotherapy, redux
- (2018) Jake S. O’Donnell et al. SEMINARS IN CANCER BIOLOGY
- Development of fisetin-loaded folate functionalized pluronic micelles for breast cancer targeting
- (2018) Atmaram Pawar et al. Artificial Cells Nanomedicine and Biotechnology
- Molecular Mechanisms and Emerging Therapeutic Targets of Triple-Negative Breast Cancer Metastasis
- (2018) Christiana Neophytou et al. Frontiers in Oncology
- Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma
- (2017) Peter Kubatka et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Drug-induced amino acid deprivation as strategy for cancer therapy
- (2017) Marcus Kwong Lam Fung et al. Journal of Hematology & Oncology
- Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity
- (2017) Lich Thi Nguyen et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
- (2017) Sung-Bae Kim et al. LANCET ONCOLOGY
- Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1
- (2017) Xueqian Zhuang et al. NATURE CELL BIOLOGY
- Notch-out for breast cancer therapies
- (2017) Márcia Lamy et al. New Biotechnology
- Rutin as A Novel c-Met Inhibitory Lead for The Control of Triple Negative Breast Malignancies
- (2017) Heba E. Elsayed et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- NF-κB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers
- (2017) Paola Poma et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- A novel chalcone-based molecule, BDP inhibits MDA-MB-231 triple-negative breast cancer cell growth by suppressing Hsp90 function
- (2017) Yong Jin Oh et al. ONCOLOGY REPORTS
- PI3K-AKT-mTOR inhibitors in breast cancers: From tumor cell signaling to clinical trials
- (2017) Nandini Dey et al. PHARMACOLOGY & THERAPEUTICS
- Maximising the potential of AKT inhibitors as anti-cancer treatments
- (2017) Jessica S. Brown et al. PHARMACOLOGY & THERAPEUTICS
- Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells
- (2017) Marcello Iriti et al. PHYTOTHERAPY RESEARCH
- The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
- (2017) Federica Fusella et al. Nature Communications
- DEK promoted EMT and angiogenesis through regulating PI3K/AKT/mTOR pathway in triple-negative breast cancer
- (2017) Yang Yang et al. Oncotarget
- Breast Cancer Cell Line Classification and Its Relevance with Breast Tumor Subtyping
- (2017) Xiaofeng Dai et al. Journal of Cancer
- Vertical inhibition of the PI3K/Akt/mTOR pathway is synergistic in breast cancer
- (2017) S-U Woo et al. Oncogenesis
- Wnt signaling in triple-negative breast cancer
- (2017) SÖ-G Pohl et al. Oncogenesis
- Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
- (2017) et al. Cancers
- The Phosphoinositide-3-Kinase-Akt-mTOR Pathway as a Therapeutic Target in Breast Cancer
- (2017) Josh Lauring et al. Journal of the National Comprehensive Cancer Network
- The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways
- (2017) Mаhmoud Youns et al. PLoS One
- Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer
- (2017) Safiulla Basha Syed et al. Scientific Reports
- Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function
- (2017) I. Kalhari Lindamulage et al. Scientific Reports
- Piperine as a Potential Anti-cancer Agent: A Review on Preclinical Studies
- (2017) Azadeh Manayi et al. CURRENT MEDICINAL CHEMISTRY
- Targeting Cellular Signaling Pathways in Breast Cancer Stem Cells and its Implication for Cancer Treatment
- (2016) BRUNO RICARDO BARRETO PIRES et al. ANTICANCER RESEARCH
- The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways
- (2016) Tilman Borggrefe et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition
- (2016) Shweta Shrivastava et al. BIOFACTORS
- Rutin inhibits proliferation, attenuates superoxide production and decreases adhesion and migration of human cancerous cells
- (2016) Mohamed ben Sghaier et al. BIOMEDICINE & PHARMACOTHERAPY
- Quercetin and Cisplatin combined treatment altered cell cycle and mitogen activated protein kinase expressions in malignant mesotelioma cells
- (2016) Asuman Demiroglu-Zergeroglu et al. BMC Complementary and Alternative Medicine
- Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer
- (2016) Andrew J. Robles et al. BREAST CANCER RESEARCH AND TREATMENT
- Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
- (2016) Ajaikumar B Kunnumakkara et al. BRITISH JOURNAL OF PHARMACOLOGY
- New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer
- (2016) Sherry X. Yang et al. CANCER TREATMENT REVIEWS
- Targeting Notch degradation system provides promise for breast cancer therapeutics
- (2016) Jing Liu et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model
- (2016) Peter Kubatka et al. EUROPEAN JOURNAL OF NUTRITION
- Genistein synergizes centchroman action in human breast cancer cells
- (2016) AnilK Balapure et al. INDIAN JOURNAL OF PHARMACOLOGY
- Quantitative phosphoproteomics reveals genistein as a modulator of cell cycle and DNA damage response pathways in triple-negative breast cancer cells
- (2016) YI FANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Curcumin inhibits invasive capabilities through epithelial mesenchymal transition in breast cancer cell lines
- (2016) Marcela Gallardo et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The Dietary Flavonoid Fisetin Causes Cell Cycle Arrest, Caspase-Dependent Apoptosis, and Enhanced Cytotoxicity of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells
- (2016) Matthew L. Smith et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors
- (2016) Patricia Mucci LoRusso JOURNAL OF CLINICAL ONCOLOGY
- Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer
- (2016) Andrew J. Robles et al. JOURNAL OF NATURAL PRODUCTS
- Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer
- (2016) S. Mohana et al. Molecular BioSystems
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- Curcumin inhibits intracellular fatty acid synthase and induces apoptosis in human breast cancer MDA-MB-231 cells
- (2016) HUIJIN FAN et al. ONCOLOGY REPORTS
- Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression
- (2016) Dan Lin et al. ONCOLOGY REPORTS
- Quercetin stimulates mitochondrial apoptosis dependent on activation of endoplasmic reticulum stress in hepatic stellate cells
- (2016) Liwei He et al. PHARMACEUTICAL BIOLOGY
- Anti-metastatic potential of resveratrol and its metabolites by the inhibition of epithelial-mesenchymal transition, migration, and invasion of malignant cancer cells
- (2016) Cho-Won Kim et al. PHYTOMEDICINE
- A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells
- (2016) Rishabh Kala et al. PLoS One
- Review of PI3K/mTOR Inhibitors Entering Clinical Trials to Treat Triple Negative Breast Cancers
- (2016) Amélie Fouqué et al. Recent Patents on Anti-Cancer Drug Discovery
- Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms
- (2016) Dona Sinha et al. SEMINARS IN CANCER BIOLOGY
- Targeting of sonic hedgehog-Gli signaling: A potential therapeutic target for patients with breast cancer
- (2016) Lingqin Song et al. Oncology Letters
- Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
- (2016) Abigail S. Krall et al. Nature Communications
- Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
- (2016) María-Dolores Canela et al. Oncotarget
- Common profiles of Notch signaling differentiate disease-free survival in luminal type A and triple negative breast cancer
- (2016) Magdalena Orzechowska et al. Oncotarget
- Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1
- (2016) Jing-Yi Chen et al. Oncotarget
- Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway
- (2016) Daniela Massihnia et al. Oncotarget
- Triple-negative breast cancer: is there a treatment on the horizon?
- (2016) Hui Yao et al. Oncotarget
- Anti-tumor activity of SL4 against breast cancer cells: induction of G2/M arrest through modulation of the MAPK-dependent p21 signaling pathway
- (2016) Li-Hui Wang et al. Scientific Reports
- Lead Phytochemicals for Anticancer Drug Development
- (2016) Sukhdev Singh et al. Frontiers in Plant Science
- The hedgehog pathway in triple-negative breast cancer
- (2016) Joyce G. Habib et al. Cancer Medicine
- Epithelial-Mesenchymal Transition and Breast Cancer
- (2016) Yanyuan Wu et al. Journal of Clinical Medicine
- Curcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast Cancer
- (2016) Amol Shindikar et al. Journal of Oncology
- Curcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt Degradation
- (2016) Feng Guan et al. PLoS One
- Combinatorial nanocarrier based drug delivery approach for amalgamation of anti-tumor agents in breast cancer cells: an improved nanomedicine strategy
- (2016) Chandran Murugan et al. Scientific Reports
- The molecular targets of resveratrol
- (2015) Sameer S. Kulkarni et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Resveratrol and cancer: Challenges for clinical translation
- (2015) Chandra K. Singh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer
- (2015) Rishabh Kala et al. BMC CANCER
- Therapeutic targets of triple-negative breast cancer: a review
- (2015) Vinayak S Jamdade et al. BRITISH JOURNAL OF PHARMACOLOGY
- Piperine inhibits the growth and motility of triple-negative breast cancer cells
- (2015) Anna L. Greenshields et al. CANCER LETTERS
- Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs
- (2015) Da-Wei Sun et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
- (2015) N. Bednarz-Knoll et al. CLINICAL CHEMISTRY
- Piperine derivatives as potential inhibitors of Survivin: An in silico molecular docking
- (2015) Elham Sattarinezhad et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Anti-cancer chalcones: Structural and molecular target perspectives
- (2015) Debarshi Kar Mahapatra et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Triple negative breast cancer chemosensitivity and chemoresistance: current advances in biomarkers indentification
- (2015) Fouzia Guestini et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice
- (2015) Zhaoguo Liu et al. FOOD AND CHEMICAL TOXICOLOGY
- Phytochemicals potently inhibit migration of metastatic breast cancer cells
- (2015) Stephanie Lemmo Ham et al. Integrative Biology
- The Combination of Rapamycin and Resveratrol Blocks Autophagy and Induces Apoptosis in Breast Cancer Cells
- (2015) Anya Alayev et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer
- (2015) Asha Srinivasan et al. MOLECULAR CARCINOGENESIS
- Soy Isoflavones and Breast Cancer Cell Lines: Molecular Mechanisms and Future Perspectives
- (2015) Alina Uifălean et al. MOLECULES
- The Multifaceted Role of Curcumin in Cancer Prevention and Treatment
- (2015) Muthu Shanmugam et al. MOLECULES
- Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases
- (2015) Yu-Jie Zhang et al. MOLECULES
- The role of TWIST1 in epithelial-mesenchymal transition and cancers
- (2015) Qing-Qing Zhu et al. TUMOR BIOLOGY
- RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model
- (2015) Adilson Kleber Ferreira et al. TUMOR BIOLOGY
- The Vacuolar ATPase a2-subunit regulates Notch signaling in triple-negative breast cancer cells
- (2015) Sahithi Pamarthy et al. Oncotarget
- Abstract 5519: Investigation of the cellular mechanisms of action of maximiscin, a novel natural product with selective cytotoxic activity against a triple negative breast cancer molecular subtype
- (2015) Andrew J. Robles et al. CANCER RESEARCH
- Combination of Phytochemicals as Adjuvants for Cancer Therapy
- (2015) John Ho et al. Recent Patents on Anti-Cancer Drug Discovery
- Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)
- (2015) Kristen M. Reipas et al. Oncotarget
- Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype
- (2015) Gyu-Beom Jang et al. Scientific Reports
- Efficacy of platinum-based chemotherapy in triple-negative breast cancer patients with metastases confined to the lungs
- (2014) Ruoxi Hong et al. ANTI-CANCER DRUGS
- Curcumin restores sensitivity to retinoic acid in triple negative breast cancer cells
- (2014) Padmamalini Thulasiraman et al. BMC CANCER
- Cancer treatment and survivorship statistics, 2014
- (2014) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Dose-dependent benefits of quercetin on tumorigenesis in the C3(1)/SV40Tag transgenic mouse model of breast cancer
- (2014) JL Steiner et al. CANCER BIOLOGY & THERAPY
- Rutin mediated targeting of signaling machinery in cancer cells
- (2014) Aliye Aras Perk et al. Cancer Cell International
- Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF-MEK-ERK Pathway in Cancer
- (2014) G. L. Johnson et al. CLINICAL CANCER RESEARCH
- Recent developments in biological activities of chalcones: A mini review
- (2014) Parvesh Singh et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- “RAF” neighborhood: Protein-protein interaction in the Raf/Mek/Erk pathway
- (2014) Botond Cseh et al. FEBS LETTERS
- ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells
- (2014) Thanh-Hung Nguyen et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Concentration-Dependent Biphasic Effects of Resveratrol on Human Natural Killer Cells in Vitro
- (2014) Qi Li et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Cyclopamine: From Cyclops Lambs to Cancer Treatment
- (2014) Stephen T. Lee et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- MicroRNAs 206 and 21 Cooperate To Promote RAS-Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1
- (2014) S. B. Sharma et al. MOLECULAR AND CELLULAR BIOLOGY
- Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
- (2014) Ji Zhang et al. MOLECULAR CELL
- Naturally occurring chalcones and their biological activities
- (2014) Zsuzsanna Rozmer et al. PHYTOCHEMISTRY REVIEWS
- NF-κB Affects Proliferation and Invasiveness of Breast Cancer Cells by Regulating CD44 Expression
- (2014) Shannon M. Smith et al. PLoS One
- Luteolin Suppresses Cancer Cell Proliferation by Targeting Vaccinia-Related Kinase 1
- (2014) Ye Seul Kim et al. PLoS One
- Combination of Cyclopamine and Tamoxifen Promotes Survival and Migration of MCF-7 Breast Cancer Cells – Interaction of Hedgehog-Gli and Estrogen Receptor Signaling Pathways
- (2014) Maja Sabol et al. PLoS One
- Combined Resveratrol, Quercetin, and Catechin Treatment Reduces Breast Tumor Growth in a Nude Mouse Model
- (2014) Alexander Schlachterman et al. Translational Oncology
- INPP4B overexpression enhances the antitumor efficacy of PARP inhibitor AG014699 in MDA-MB-231 triple-negative breast cancer cells
- (2014) Ying Sun et al. TUMOR BIOLOGY
- Resveratrol reverses multidrug resistance in human breast cancer doxorubicin-resistant cells
- (2014) FANG HUANG et al. Experimental and Therapeutic Medicine
- Curcumin: A Potential Candidate in Prevention of Cancer via Modulation of Molecular Pathways
- (2014) Arshad H. Rahmani et al. Biomed Research International
- KIF14 Promotes AKT Phosphorylation and Contributes to Chemoresistance in Triple-Negative Breast Cancer
- (2014) Stina M. Singel et al. NEOPLASIA
- Molecular and Cellular Heterogeneity in Breast Cancer
- (2013) Ashley G. Rivenbark et al. AMERICAN JOURNAL OF PATHOLOGY
- Targeted Therapy for Breast Cancer
- (2013) Ali Mohamed et al. AMERICAN JOURNAL OF PATHOLOGY
- Molecular Basis of NF-κB Signaling
- (2013) Johanna Napetschnig et al. Annual Review of Biophysics
- Low Expression of Tyrosine-protein Phosphatase Nonreceptor Type 12 is Associated with Lymph Node Metastasis and Poor Prognosis in Operable Triple-negative Breast Cancer
- (2013) Min-Qing Wu et al. Asian Pacific Journal of Cancer Prevention
- Luteolin exhibits anti-inflammatory effects by blocking the activity of heat shock protein 90 in macrophages
- (2013) Dan Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Natural products: A continuing source of novel drug leads
- (2013) Gordon M. Cragg et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin
- (2013) Tae Hyung Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Regulation of angiogenesis via Notch signaling in breast cancer and cancer stem cells
- (2013) Weiqiang Zhou et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Wnt signaling in triple negative breast cancer is associated with metastasis
- (2013) Nandini Dey et al. BMC CANCER
- Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
- (2013) Z. C. Hartman et al. CANCER RESEARCH
- Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer
- (2013) Kamal S. Saini et al. CANCER TREATMENT REVIEWS
- 2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells
- (2013) Sun Young Kim et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells
- (2013) Rajeshwari R. Mehta et al. CLINICAL & EXPERIMENTAL METASTASIS
- Molecular Pathways: PI3K Pathway Targets in Triple-Negative Breast Cancers
- (2013) V. Gordon et al. CLINICAL CANCER RESEARCH
- Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence
- (2013) Joao Tomé-Carneiro et al. CURRENT PHARMACEUTICAL DESIGN
- Curcumin-derivative nanomicelles for the treatment of triple negative breast cancer
- (2013) Sebastien Taurin et al. JOURNAL OF DRUG TARGETING
- The complexity of NF-κB signaling in inflammation and cancer
- (2013) Bastian Hoesel et al. Molecular Cancer
- The mechanisms of Hedgehog signalling and its roles in development and disease
- (2013) James Briscoe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells
- (2013) M F Kendellen et al. ONCOGENE
- Maximiscin, a Novel Shikimate-Polyketide-NRPS Hybrid Metabolite Obtained from Tolypocladium Sp. with Potent Antitumor Activities
- (2013) L Du et al. PLANTA MEDICA
- Deguelin Action Involves c-Met and EGFR Signaling Pathways in Triple Negative Breast Cancer Cells
- (2013) Rajeshwari Mehta et al. PLoS One
- Differential Activation of Wnt-β-Catenin Pathway in Triple Negative Breast Cancer Increases MMP7 in a PTEN Dependent Manner
- (2013) Nandini Dey et al. PLoS One
- Anti-Tumor Effect of Rutin on Human Neuroblastoma Cell Lines through Inducing G2/M Cell Cycle Arrest and Promoting Apoptosis
- (2013) Hongyan Chen et al. TheScientificWorldJOURNAL
- Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil
- (2013) B S Vinod et al. Cell Death & Disease
- Effects of quercetin on the proliferation of breast cancer cells and expression of survivin in vitro
- (2013) XIAO-HUI DENG et al. Experimental and Therapeutic Medicine
- Cyclopamine is a novel Hedgehog signaling inhibitor with significant anti-proliferative, anti-invasive and anti-estrogenic potency in human breast cancer cells
- (2013) JUN CHE et al. Oncology Letters
- Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
- (2013) Panhong Fan et al. Stem Cell Research & Therapy
- Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials
- (2012) Subash C. Gupta et al. AAPS Journal
- Fisetin: A Dietary Antioxidant for Health Promotion
- (2012) Naghma Khan et al. ANTIOXIDANTS & REDOX SIGNALING
- Defining biomarkers to predict sensitivity to PI3K/Akt/mTOR pathway inhibitors in breast cancer
- (2012) A.M. Gonzalez-Angulo et al. CANCER TREATMENT REVIEWS
- Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells
- (2012) Maria Theresa E. Montales et al. CARCINOGENESIS
- Cycle arrest and apoptosis in MDA-MB-231/Her2 cells induced by curcumin
- (2012) Shih-Han Sun et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- NF- B, the first quarter-century: remarkable progress and outstanding questions
- (2012) M. S. Hayden et al. GENES & DEVELOPMENT
- Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway
- (2012) HONG PAN et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Anticancer activities of genistein-topotecan combination in prostate cancer cells
- (2012) Vanessa Hörmann et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Dissecting the Heterogeneity of Triple-Negative Breast Cancer
- (2012) Otto Metzger-Filho et al. JOURNAL OF CLINICAL ONCOLOGY
- Piperine, a dietary phytochemical, inhibits angiogenesis
- (2012) Carolyn D. Doucette et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Expression of Wnt3 Activates Wnt/ -Catenin Pathway and Promotes EMT-like Phenotype in Trastuzumab-Resistant HER2-Overexpressing Breast Cancer Cells
- (2012) Y. Wu et al. MOLECULAR CANCER RESEARCH
- Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression
- (2012) XIAO-DONG SUN et al. Molecular Medicine Reports
- A Comprehensive Review of the Carcinogenic and Anticarcinogenic Potential of Capsaicin
- (2012) Keith Bley et al. TOXICOLOGIC PATHOLOGY
- Modulating the vascular behavior of metastatic breast cancer cells by curcumin treatment
- (2012) Anna L. Palange et al. Frontiers in Oncology
- mTOR in breast cancer: Differential expression in triple-negative and non-triple-negative tumors
- (2011) S. Walsh et al. BREAST
- Hedgehog Signaling Inhibition Blocks Growth of Resistant Tumors through Effects on Tumor Microenvironment
- (2011) E. Heller et al. CANCER RESEARCH
- The Two Faces of Capsaicin
- (2011) A. M. Bode et al. CANCER RESEARCH
- Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase
- (2011) Tingting Sun et al. CELL
- Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction
- (2011) HC Chang et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Notch-1 and Notch-4 Biomarker Expression in Triple-Negative Breast Cancer
- (2011) Jodi Speiser et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Resveratrol Modulates MED28 (Magicin/EG-1) Expression and Inhibits Epidermal Growth Factor (EGF)-Induced Migration in MDA-MB-231 Human Breast Cancer Cells
- (2011) Ming-Fen Lee et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The wnt/β-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer
- (2011) Taj D. King et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Combinatorial Effects of Lapatinib and Rapamycin in Triple-Negative Breast Cancer Cells
- (2011) T. Liu et al. MOLECULAR CANCER THERAPEUTICS
- Anti-carcinogenic Effects of the Flavonoid Luteolin
- (2011) Günter Seelinger et al. MOLECULES
- Crosstalk in NF-κB signaling pathways
- (2011) Andrea Oeckinghaus et al. NATURE IMMUNOLOGY
- Tumor Cell Growth Inhibition Is Correlated With Levels of Capsaicin Present in Hot Peppers
- (2011) Dan Dou et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Induction of apoptotic cell death by phytoestrogens by up-regulating the levels of phospho-p53 and p21 in normal and malignant estrogen receptor α–negative breast cells
- (2011) Hye-Sook Seo et al. NUTRITION RESEARCH
- FZD7 has a critical role in cell proliferation in triple negative breast cancer
- (2011) L Yang et al. ONCOGENE
- Triple-Negative Breast Cancer: An Unmet Medical Need
- (2011) C. A. Hudis et al. ONCOLOGIST
- Resistance to MEK Inhibitors: Should We Co-Target Upstream?
- (2011) P. I. Poulikakos et al. Science Signaling
- GSK-3: Functional Insights from Cell Biology and Animal Models
- (2011) Oksana Kaidanovich-Beilin et al. Frontiers in Molecular Neuroscience
- Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome
- (2010) Andrey I. Khramtsov et al. AMERICAN JOURNAL OF PATHOLOGY
- The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation
- (2010) Alexander Plotnikov et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Role of Notch and its oncogenic signaling crosstalk in breast cancer
- (2010) Shanchun Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
- (2010) Mathilde Bayet-Robert et al. CANCER BIOLOGY & THERAPY
- Triple-Negative Breast Cancer
- (2010) Steven J. Isakoff CANCER JOURNAL
- Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling
- (2010) Xin He et al. CANCER LETTERS
- Cocarcinogenic Effect of Capsaicin Involves Activation of EGFR Signaling but Not TRPV1
- (2010) M. K. Hwang et al. CANCER RESEARCH
- The Canonical NF- B Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
- (2010) M. Liu et al. CANCER RESEARCH
- A Wnt-ow of Opportunity: Targeting the Wnt/β-Catenin Pathway in Breast Cancer
- (2010) Jenifer R. Prosperi et al. CURRENT DRUG TARGETS
- Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo
- (2010) Masayuki Fukui et al. EUROPEAN JOURNAL OF CANCER
- Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells
- (2010) Wen-Feng Hua et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death
- (2010) Masayuki Fukui et al. FREE RADICAL BIOLOGY AND MEDICINE
- Resveratrol commonly displays hormesis: Occurrence and biomedical significance
- (2010) Edward J Calabrese et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Enhanced Anti-tumor Activity by the Combination of the Natural Compounds (−)-Epigallocatechin-3-gallate and Luteolin
- (2010) A. R. M. Ruhul Amin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Investigation of Effects of Quercetin and Its Combination with Cisplatin on Malignant Mesothelioma Cells In Vitro
- (2010) A. Demiroglu-Zergeroglu et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
- (2010) Felipe C Geyer et al. MODERN PATHOLOGY
- Notch Signaling Pathway as a Therapeutic Target in Breast Cancer
- (2010) H. Al-Hussaini et al. MOLECULAR CANCER THERAPEUTICS
- Growth-stimulatory effect of resveratrol in human cancer cells
- (2010) Masayuki Fukui et al. MOLECULAR CARCINOGENESIS
- LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy
- (2010) C.-C. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-inflammatory and Anticarcinogenic Effect of Genistein Alone or in Combination with Capsaicin in TPA-Treated Rat Mammary Glands or Mammary Cancer Cell Line
- (2009) Jin-Tack Hwang et al. Annals of the New York Academy of Sciences
- The ERK signaling cascade-Views from different subcellular compartments
- (2009) Zhong Yao et al. BIOFACTORS
- Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes
- (2009) Eve Gazave et al. BMC EVOLUTIONARY BIOLOGY
- Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
- (2009) Madhuri Kakarala et al. BREAST CANCER RESEARCH AND TREATMENT
- Deguelin Inhibits Growth of Breast Cancer Cells by Modulating the Expression of Key Members of the Wnt Signaling Pathway
- (2009) G. Murillo et al. Cancer Prevention Research
- Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials
- (2009) A. Bishayee Cancer Prevention Research
- Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition
- (2009) O. K. Mirzoeva et al. CANCER RESEARCH
- New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells
- (2009) Li Lin et al. CANCER SCIENCE
- Hedgehog signalling in breast cancer
- (2009) M. Kasper et al. CARCINOGENESIS
- Profiling the Human Protein-DNA Interactome Reveals ERK2 as a Transcriptional Repressor of Interferon Signaling
- (2009) Shaohui Hu et al. CELL
- Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/β-catenin signaling
- (2009) Chandra P. Prasad et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Biology, Metastatic Patterns, and Treatment of Patients with Triple-Negative Breast Cancer
- (2009) Carey K. Anders et al. Clinical Breast Cancer
- In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models
- (2009) K. P. Hoeflich et al. CLINICAL CANCER RESEARCH
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells
- (2009) Su-Yu Chien et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- A review on plant-derived natural products and their analogs with anti-tumor activity
- (2009) KK Dholwani et al. INDIAN JOURNAL OF PHARMACOLOGY
- Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines
- (2009) Kathryn Balmanno et al. INTERNATIONAL JOURNAL OF CANCER
- Combination Treatment with Luteolin and Quercetin Enhances Antiproliferative Effects in Nicotine-Treated MDA-MB-231 Cells by Down-regulating Nicotinic Acetylcholine Receptors
- (2009) Yung-Leun Shih et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents
- (2009) Neeraj Mahindroo et al. JOURNAL OF MEDICINAL CHEMISTRY
- Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway
- (2009) N H Thoennissen et al. ONCOGENE
- Genistein in the Presence of 17β-Estradiol Inhibits Proliferation of ERβ Breast Cancer Cells
- (2009) Talitha T. Rajah et al. PHARMACOLOGY
- Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFκB, cyclinD and MMP-1 transcription
- (2009) Q. Liu et al. PHYTOMEDICINE
- The Wnt Co-Receptor Lrp6 Is Required for Normal Mouse Mammary Gland Development
- (2009) Charlotta Lindvall et al. PLoS One
- Erk1 and Erk2 Regulate Endothelial Cell Proliferation and Migration during Mouse Embryonic Angiogenesis
- (2009) Ruchika Srinivasan et al. PLoS One
- Antiproliferative effects of quercetin through cell cycle arrest and apoptosis in human breast cancer MDA-MB-453 cells
- (2008) Eun Jeong Choi et al. ARCHIVES OF PHARMACAL RESEARCH
- Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)
- (2008) Xiaomei Zhang et al. BREAST CANCER RESEARCH AND TREATMENT
- Enhancement Radiosensitization of Breast Cancer Cells by Deguelin
- (2008) Tongbo Yi et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Multi-targeted therapy of cancer by genistein
- (2008) Sanjeev Banerjee et al. CANCER LETTERS
- Curcumin: From ancient medicine to current clinical trials
- (2008) H. Hatcher et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy
- (2008) Yong Lin et al. CURRENT CANCER DRUG TARGETS
- Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
- (2008) Arkaitz Carracedo et al. JOURNAL OF CLINICAL INVESTIGATION
- Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer
- (2008) Cornelia Liedtke et al. JOURNAL OF CLINICAL ONCOLOGY
- Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ERα/ERβ ratio
- (2008) A.M. Sotoca et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Cancer survival in five continents: a worldwide population-based study (CONCORD)
- (2008) Michel P Coleman et al. LANCET ONCOLOGY
- Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration
- (2008) Mariona Graupera et al. NATURE
- Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis
- (2008) Shidong Jia et al. NATURE
- Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway
- (2008) Zhong Li et al. TOXICOLOGY IN VITRO
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