A Comprehensive Review of the Carcinogenic and Anticarcinogenic Potential of Capsaicin

Novel Penetration Enhancers for Skin Applications: A Review

(2012) Rabinarayan Parhi et al.   Current Drug Delivery

Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch

(2011) P. Anand et al.   BRITISH JOURNAL OF ANAESTHESIA

The Two Faces of Capsaicin

(2011) A. M. Bode et al.   CANCER RESEARCH

Capsaicin promotes a more aggressive gene expression phenotype and invasiveness in null-TRPV1 urothelial cancer cells

(2011) Sara Caprodossi et al.   CARCINOGENESIS

Down-Regulation of Tumor-Associated NADH Oxidase, tNOX (ENOX2), Enhances Capsaicin-Induced Inhibition of Gastric Cancer Cell Growth

(2011) His-Ming Wang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction

(2011) HC Chang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Suppression of Tumor Necrosis Factor-α-Induced Nuclear Factor κB Activation and Aromatase Activity by Capsaicin and Its Analog Capsazepine

(2011) Suaib Luqman et al.   JOURNAL OF MEDICINAL FOOD

Capsaicin Induces Apoptosis of Cisplatin-Resistant Stomach Cancer Cells by Causing Degradation of Cisplatin-Inducible Aurora-A Protein

(2011) Hui-Chung Huh et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Tumor Cell Growth Inhibition Is Correlated With Levels of Capsaicin Present in Hot Peppers

(2011) Dan Dou et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids

(2011) Berrin Özçelik et al.   PHARMACEUTICAL BIOLOGY

Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells

(2011) Kartick C. Pramanik et al.   PLoS One

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

Cocarcinogenic Effect of Capsaicin Involves Activation of EGFR Signaling but Not TRPV1

(2010) M. K. Hwang et al.   CANCER RESEARCH

NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3 , C/EBP  and ATF3

(2010) S. H. Lee et al.   CARCINOGENESIS

Capsaicin Dermal Patch

(2010) Paul L. McCormack   DRUGS

Mitochondrial Ca2+ sequestration and precipitation revisited

(2010) Christos Chinopoulos et al.   FEBS Journal

Effect of capsaicin on prostate cancer cells

(2010) Inés Díaz-Laviada   Future Oncology

Capsaicin: A novel chemopreventive molecule and its underlying molecular mechanisms of action

(2010) AA Oyagbemi et al.   INDIAN JOURNAL OF CANCER

Antitumor Activity of Capsaicin on Human Colon Cancer Cells in Vitro and Colo 205 Tumor Xenografts in Vivo

(2010) Hsu-Feng Lu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated Apoptosis

(2010) C.-H. Choi et al.   MOLECULAR PHARMACOLOGY

Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway

(2010) Kathleen C. Brown et al.   PLoS One

Genetic variants involved in gallstone formation and capsaicin metabolism, and the risk of gallbladder cancer in Chilean women

(2010) Sergio Báez   WORLD JOURNAL OF GASTROENTEROLOGY

Inhibition and induction of human cytochrome P450 enzymesin vitroby capsaicin

(2010) Sunita Babbar et al.   XENOBIOTICA

Anti-inflammatory and Anticarcinogenic Effect of Genistein Alone or in Combination with Capsaicin in TPA-Treated Rat Mammary Glands or Mammary Cancer Cell Line

(2009) Jin-Tack Hwang et al.   Annals of the New York Academy of Sciences

Ameliorating effect of capsaicin on alterations in lipid metabolism during mice lung carcinoma

(2009) P. Anandakumar et al.   ARCHIVES OF PHARMACAL RESEARCH

Chemopreventive Task of Capsaicin against Benzo(a)pyrene-induced Lung Cancer in Swiss Albino Mice

(2009) Pandi Anandakumar et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Cancer type-specific tNOX isoforms: A putative family of redox protein splice variants with cancer diagnostic and prognostic potential

(2009) D. James Morré et al.   BIOFACTORS

Effect of Ccapsaicin on tNOX (ENOX2) protein expression in stomach cancer cells

(2009) Hsi-Ming Wang et al.   BIOFACTORS

Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis

(2009) Amiya K. Ghosh et al.   CANCER LETTERS

Transient Receptor Potential Type Vanilloid 1 Suppresses Skin Carcinogenesis

(2009) A. M. Bode et al.   CANCER RESEARCH

Roles of Nox1 and other Nox isoforms in cancer development

(2009) Tohru Kamata   CANCER SCIENCE

Capsaicin sensitizes malignant glioma cells to TRAIL-mediated apoptosis via DR5 upregulation and survivin downregulation

(2009) Jin Yeop Kim et al.   CARCINOGENESIS

Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner

(2009) C. Amantini et al.   CARCINOGENESIS

Biotransformation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Lung Tissue from Mouse, Rat, Hamster, and Man

(2009) Elmar Richter et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway

(2009) Dong-Hoon Shin et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Lysosomal abnormalities during benzo(a)pyrene-induced experimental lung carcinogenesis - defensive role of capsaicin

(2009) P. Anandakumar et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis

(2009) P. Anandakumar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Effect of capsaicin on glucose metabolism studied in experimental lung carcinogenesis

(2009) P. Anandakumar et al.   NATURAL PRODUCT RESEARCH

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

(2009) N H Thoennissen et al.   ONCOGENE

The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation

(2009) Khadija Alawi et al.   PHARMACOLOGY & THERAPEUTICS

Pharmacokinetic Analysis of Capsaicin After Topical Administration of a High-Concentration Capsaicin Patch to Patients With Peripheral Neuropathic Pain

(2009) Sunita Babbar et al.   THERAPEUTIC DRUG MONITORING

Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways

(2009) Mi-Ja Lee et al.   TOXICOLOGY

Capsaicin Mediates Cell Death in Bladder Cancer T24 Cells Through Reactive Oxygen Species Production and Mitochondrial Depolarization

(2009) Zhong-Hua Yang et al.   UROLOGY

In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

(2008) Ruifen Zhang et al.   APOPTOSIS

Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: A microarray study

(2008) Ana María Sánchez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Cloning and Characterization of a Candidate Human Growth-Related and Time-Keeping Constitutive Cell Surface Hydroquinone (NADH) Oxidase

(2008) Ziying Jiang et al.   BIOCHEMISTRY

The concept of neurogenic inflammation

(2008) Pierangelo Geppetti et al.   BJU INTERNATIONAL

Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose

(2008) R. Scott Obach et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Antioxidant and Iron-Binding Properties of Curcumin, Capsaicin, andS-Allylcysteine Reduce Oxidative Stress in Rat Brain Homogenate

(2008) Amichand Dairam et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Beneficial influence of capsaicin on lipid peroxidation, membrane-bound enzymes and glycoprotein profile during experimental lung carcinogenesis

(2008) P. Anandakumar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Capsaicin induces apoptosis and terminal differentiation in human glioma A172 cells

(2008) Young-Gi Gil et al.   LIFE SCIENCES

Cancer chemoprevention and mitochondria: Targeting apoptosis in transformed cellsviathe disruption of mitochondrial bioenergetics/redox state

(2008) Numsen Hail et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Capsaicin modulates pulmonary antioxidant defense system during benzo(a)pyrene-induced lung cancer in swiss albino mice

(2008) P. Anandakumar et al.   PHYTOTHERAPY RESEARCH

A comparative proteomic analysis for capsaicin-induced apoptosis between human hepatocarcinoma (HepG2) and human neuroblastoma (SK-N-SH) cells

(2008) Yu Mi Baek et al.   PROTEOMICS

Stabilization of pulmonary mitochondrial enzyme system by capsaicin during benzo(a)pyrene induced experimental lung cancer

(2007) P. Anandakumar et al.   BIOMEDICINE & PHARMACOTHERAPY