Fishing for fire: strategies for biological targeting and criteria for material design in anti-inflammatory therapies
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Title
Fishing for fire: strategies for biological targeting and criteria for material design in anti-inflammatory therapies
Authors
Keywords
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Journal
POLYMERS FOR ADVANCED TECHNOLOGIES
Volume 25, Issue 5, Pages 478-498
Publisher
Wiley
Online
2014-04-08
DOI
10.1002/pat.3264
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- (2015) P.K. Shrivastava et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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- (2013) Omri Wolk et al. Expert Opinion on Drug Delivery
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- (2013) Daniela Impellizzeri et al. EXPERT OPINION ON THERAPEUTIC TARGETS
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- (2012) Pieter J. Gaillard et al. JOURNAL OF CONTROLLED RELEASE
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- (2012) Caroline de Gracia Lux et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2012) Debashish Roy et al. Polymer Chemistry
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- (2012) Zohreh Amoozgar et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
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- (2011) Ivana Celardo et al. ACS Nano
- Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomography/computed tomography
- (2011) Tom M. Piscaer et al. ARTHRITIS AND RHEUMATISM
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- (2011) Nynke A. Jager et al. AUTOIMMUNITY REVIEWS
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- (2011) Dianhua Jiang et al. PHYSIOLOGICAL REVIEWS
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- (2011) C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- αvβ3 integrin and angiogenesis: a moody integrin in a changing environment
- (2008) Kairbaan Hodivala-Dilke CURRENT OPINION IN CELL BIOLOGY
- Dexamethasone–pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers
- (2008) Simon Keely et al. JOURNAL OF CONTROLLED RELEASE
- Induction and exacerbation of psoriasis with TNF-blockade therapy: A review and analysis of 127 cases
- (2008) Justin M. Ko et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Oligopeptide-based amide functional initiators for ATRP
- (2008) Dave J. Adams et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Acetal-Derivatized Dextran: An Acid-Responsive Biodegradable Material for Therapeutic Applications
- (2008) Eric M. Bachelder et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enhanced Anti-Inflammation of Inhaled Dexamethasone Palmitate Using Mannosylated Liposomes in an Endotoxin-Induced Lung Inflammation Model
- (2008) W. Wijagkanalan et al. MOLECULAR PHARMACOLOGY
- Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers
- (2008) Silvia Muro et al. MOLECULAR THERAPY
- Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage
- (2008) Dominique A. Rothenfluh et al. NATURE MATERIALS
- Synthesis and Evaluation of a Well-defined HPMA Copolymer–Dexamethasone Conjugate for Effective Treatment of Rheumatoid Arthritis
- (2008) Xin-Ming Liu et al. PHARMACEUTICAL RESEARCH
- CD44v4 Is a Major E-Selectin Ligand that Mediates Breast Cancer Cell Transendothelial Migration
- (2008) Ke Zen et al. PLoS One
- Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN
- (2008) S.-K. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oxidation-responsiveness of nanomaterials for targeting inflammatory reactions
- (2008) Vitaliy V. Khutoryanskiy et al. PURE AND APPLIED CHEMISTRY
- Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies
- (2008) Ulrich Förstermann Nature clinical practice. Cardiovascular medicine
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