Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis

Targeted Dendrimeric Anticancer Prodrug: A Methotrexate-Folic Acid-Poly(amidoamine) Conjugate and a Novel, Rapid, “One Pot” Synthetic Approach

(2010) Yuehua Zhang et al.   BIOCONJUGATE CHEMISTRY

Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates

(2009) Andrzej Myc et al.   ANTI-CANCER DRUGS

The future of folic acid antagonist therapy in rheumatoid arthritis

(2009) Christoph Fiehn   ARTHRITIS AND RHEUMATISM

Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

(2009) Joost W. Van Der Heijden et al.   ARTHRITIS AND RHEUMATISM

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

(2009) John A. Hamilton et al.   ARTHRITIS AND RHEUMATISM

Cationic Poly(amidoamine) Dendrimer Induces Lysosomal Apoptotic Pathway at Therapeutically Relevant Concentrations

(2009) Thommey P. Thomas et al.   BIOMACROMOLECULES

Folate Receptor   Is Expressed by Tumor-Associated Macrophages and Constitutes a Marker for M2 Anti-inflammatory/Regulatory Macrophages

(2009) A. Puig-Kroger et al.   CANCER RESEARCH

Dendrimers: Emerging polymers for drug-delivery systems

(2009) Basavaraj K. Nanjwade et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages

(2008) W. Xia et al.   BLOOD

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

(2008) Petra Bohanec Grabar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Investigation of tumor cell targeting of a dendrimer nanoparticle using a double-clad optical fiber probe

(2008) Thommey P. Thomas et al.   JOURNAL OF BIOMEDICAL OPTICS

Treatment of rheumatoid arthritis: a global perspective on the use of antirheumatic drugs

(2008) Tuulikki Sokka et al.   Modern Rheumatology

Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases

(2007) Philip S. Low et al.   ACCOUNTS OF CHEMICAL RESEARCH