Systemic Delivery of Small Interfering RNA Targeting the Interleukin-2/15 Receptor β Chain Prevents Disease Progression in Experimental Arthritis

Silencing TNF-α in macrophages and dendritic cells for arthritis treatment

(2013) C Ye et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Genetic variants inIL15associate with progression of joint destruction in rheumatoid arthritis: a multicohort study

(2012) R Knevel et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments

(2012) Fabien Dépis et al.   ARTHRITIS AND RHEUMATISM

In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier

(2012) Broes Naeye et al.   BIOMATERIALS

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

(2012) Georg Schett et al.   Nature Reviews Rheumatology

Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane

(2012) J. E. Zuckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designing micro- and nano-particles for treating rheumatoid arthritis

(2011) Samir Mitragotri et al.   ARCHIVES OF PHARMACAL RESEARCH

The promotion of siRNA delivery to breast cancer overexpressing epidermal growth factor receptor through anti-EGFR antibody conjugation by immunoliposomes

(2011) Jie Gao et al.   BIOMATERIALS

Interleukin 15 Levels in Serum May Predict a Severe Disease Course in Patients with Early Arthritis

(2011) Isidoro González-Álvaro et al.   PLoS One

Enhanced Gene Delivery and siRNA Silencing by Gold Nanoparticles Coated with Charge-Reversal Polyelectrolyte

(2010) Shutao Guo et al.   ACS Nano

State-of-the-art: rheumatoid arthritis

(2010) I. B. McInnes et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-15 receptor-directed immunotoxins atteunuate disease severity in rat adjuvant arthritis

(2010) Deling Wang et al.   MOLECULAR IMMUNOLOGY

Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population

(2009) F A S Kurreeman et al.   ANNALS OF THE RHEUMATIC DISEASES

Tissue- and Organ-Selective Biodistribution of NIR Fluorescent Quantum Dots

(2009) Hak Soo Choi et al.   NANO LETTERS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Efficient suppression of murine arthritis by combined anticytokine small interfering RNA lipoplexes

(2008) Maroun Khoury et al.   ARTHRITIS AND RHEUMATISM

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Chitosan/siRNA Nanoparticle–mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model

(2008) Kenneth A Howard et al.   MOLECULAR THERAPY

Systemic Delivery of DNA or siRNA Mediated by Linear Polyethylenimine (L-PEI) Does Not Induce an Inflammatory Response

(2008) Marie-Elise Bonnet et al.   PHARMACEUTICAL RESEARCH

Neutralizing IL-21 and IL-15 Inhibits Pro-inflammatory Cytokine Production in Rheumatoid Arthritis

(2008) A. K. Andersson et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY