Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor

Intercellular Adhesion Molecule 1 Engagement Modulates Sphingomyelinase and Ceramide, Supporting Uptake of Drug Carriers by the Vascular Endothelium

(2012) Daniel Serrano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein

(2011) Jeff Zhiqiang Lu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Brain delivery and cellular internalization mechanisms for transferrin conjugated biodegradable polymersomes

(2011) Zhiqing Pang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Reversal of Lysosomal Storage in Brain of Adult MPS-I Mice with Intravenous Trojan Horse-Iduronidase Fusion Protein

(2011) Ruben J. Boado et al.   MOLECULAR PHARMACEUTICS

Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders

(2011) Janet Hsu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain

(2010) Inge van Rooy et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease

(2010) Janet Hsu et al.   JOURNAL OF CONTROLLED RELEASE

Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers

(2010) Andres J. Calderon et al.   JOURNAL OF CONTROLLED RELEASE

Biopharmaceutical drug targeting to the brain

(2010) William M. Pardridge   JOURNAL OF DRUG TARGETING

New biotechnological and nanomedicine strategies for treatment of lysosomal storage disorders

(2010) Silvia Muro   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse

(2008) Ruben J. Boado et al.   BIOTECHNOLOGY AND BIOENGINEERING

Lysosomal Storage Diseases and the Blood-Brain Barrier

(2008) David Begley et al.   CURRENT PHARMACEUTICAL DESIGN

Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms

(2008) Olga Barreiro et al.   JOURNAL OF CELL BIOLOGY

Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes

(2008) C GARNACHO et al.   JOURNAL OF CONTROLLED RELEASE

Liposome encapsulated polyethylenimine/ODN polyplexes for brain targeting

(2008) Young Tag Ko et al.   JOURNAL OF CONTROLLED RELEASE

Non-inhibitory antibodies impede lysosomal storage reduction during enzyme replacement therapy of a lysosomal storage disease

(2008) Ulrich Matzner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer Nanocarriers

(2008) C. Garnacho et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Reduced α-Gal A enzyme activity in Fabry fibroblast cells and Fabry mice tissues induced by serum from antibody positive patients with Fabry disease

(2008) Toya Ohashi et al.   MOLECULAR GENETICS AND METABOLISM

Globotriaosylceramide induces oxidative stress and up-regulates cell adhesion molecule expression in Fabry disease endothelial cells

(2008) Jin-Song Shen et al.   MOLECULAR GENETICS AND METABOLISM

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

Targeting of the CNS in MPS-IH Using a Nonviral Transferrin-α-l-iduronidase Fusion Gene Product

(2008) Mark J Osborn et al.   MOLECULAR THERAPY

Aptamer-based endocytosis of a lysosomal enzyme

(2008) C.-h. B. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular uptake and lysosomal delivery of galactocerebrosidase tagged with the HIV Tat protein transduction domain

(2007) Xian-Yang Zhang et al.   JOURNAL OF NEUROCHEMISTRY