Molecular Signatures of the Insulin-like Growth Factor 1-mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers

Biomarker assessment of the CBCSG006 trial: a randomized phase III trial of cisplatin plus gemcitabine compared with paclitaxel plus gemcitabine as first-line therapy for patients with metastatic triple-negative breast cancer

(2018) J Zhang et al.   ANNALS OF ONCOLOGY

Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling

(2018) Yanmei Yi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chemotherapeutic agents for the treatment of metastatic breast cancer: An update

(2018) Mariam Abotaleb et al.   BIOMEDICINE & PHARMACOTHERAPY

Proposed Molecular and miRNA Classification of Gastric Cancer

(2018) Lara Alessandrini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Pattern of Signatures in Gastric Cancer Prognosis

(2018) Julita Machlowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

(2018) Claudia Allemani et al.   LANCET

Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway

(2018) Haim Werner et al.   Molecular Cancer

Prognostic and predictive blood biomarkers in gastric cancer and the potential application of circulating tumor cells

(2018) Ting-Ting Li et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The intrinsically disordered E-domains regulate the IGF-1 prohormones stability, subcellular localisation and secretion

(2018) Giosuè Annibalini et al.   Scientific Reports

A Functional Interplay between IGF-1 and Adiponectin

(2017) Stefania Orrù et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights

(2017) Heming Li et al.   Molecular Cancer

IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling

(2017) Yong Antican Wang et al.   MOLECULAR CANCER RESEARCH

Lymph nodes ratio based nomogram predicts survival of resectable gastric cancer regardless of the number of examined lymph nodes

(2017) Shangxiang Chen et al.   Oncotarget

Epithelial-to-mesenchymal transition, circulating tumor cells and cancer metastasis: Mechanisms and clinical applications

(2017) Xiao-Xiang Jie et al.   Oncotarget

Deciphering Epithelial–Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

(2017) Gerhard A. Burger et al.   Frontiers in Oncology

The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics

(2016) Ting-Yuan David Cheng et al.   Journal of Thoracic Oncology

Exercise Activates p53 and Negatively Regulates IGF-1 Pathway in Epidermis within a Skin Cancer Model

(2016) Miao Yu et al.   PLoS One

The insulin-like growth factor-I receptor (IGF-IR) in breast cancer: biology and treatment strategies

(2016) Morteza Motallebnezhad et al.   TUMOR BIOLOGY

TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1

(2016) Shilhav Meisel Sharon et al.   Oncotarget

Type I insulin-like growth factor receptor signaling in hematological malignancies

(2016) Deeksha Vishwamitra et al.   Oncotarget

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX

(2016) Sung Yong Oh et al.   Oncotarget

Clinical and Translational Results of a Phase II, Randomized Trial of an Anti-IGF-1R (Cixutumumab) in Women with Breast Cancer That Progressed on Endocrine Therapy

(2015) W. J. Gradishar et al.   CLINICAL CANCER RESEARCH

IGF2 signaling and regulation in cancer

(2015) Jurriaan Brouwer-Visser et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Increased insulin-like growth factor 1 receptor (IGF1R) expression in small cell lung cancer and the effect of inhibition of IGF1R expression by RNAi on growth of human small cell lung cancer NCI-H446 cell

(2015) Zhigang Wang et al.   GROWTH FACTORS

Clinical significance of IGF1R gene expression in patients with Stage II/III gastric cancer who receive curative surgery and adjuvant chemotherapy with S-1

(2015) Koji Numata et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Relationship between expression of IGFBP7 and clinicopathological variables in gastric cancer

(2015) Yuya Sato et al.   JOURNAL OF CLINICAL PATHOLOGY

Molecular effects of supraphysiological doses of doping agents on health

(2015) Esther Imperlini et al.   Molecular BioSystems

The role of the insulin-like growth factor-1 system in breast cancer

(2015) Panagiotis F Christopoulos et al.   Molecular Cancer

Synergistic effect of DHT and IGF-1 hyperstimulation in human peripheral blood lymphocytes

(2015) Esther Imperlini et al.   PROTEOMICS

The involvement of survivin in insulin-like growth factor 1-induced epithelial-mesenchymal transition in gastric cancer

(2015) Chengjun Li et al.   TUMOR BIOLOGY

Human IGF1 pro-forms induce breast cancer cell proliferation via the IGF1 receptor

(2015) Mauro De Santi et al.   CELLULAR ONCOLOGY

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway

(2015) Roberta Matà et al.   Oncotarget

FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells

(2015) LaTonia Taliaferro-Smith et al.   Oncotarget

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer

(2015) Juan Zhou et al.   Oncotarget

Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation

(2015) Susan M. Farabaugh et al.   Frontiers in Endocrinology

Mechanisms of resistance to EGFR tyrosine kinase inhibitors

(2015) Lihua Huang et al.   Acta Pharmaceutica Sinica B

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1

(2015) Soo-Im Choi et al.   Oncotarget

Treatment with insulin-like growth factor 1 receptor inhibitor reverses hypoxia-induced epithelial–mesenchymal transition in non-small cell lung cancer

(2014) Fariz Nurwidya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IGF-1-induced epithelial–mesenchymal transition in MCF-7 cells is mediated by MUC1

(2014) Gaoyong Liao et al.   CELLULAR SIGNALLING

Relevance of insulin-like growth factor 1 receptor gene expression as a prognostic factor in non-small-cell lung cancer

(2014) M. Teresa Agulló-Ortuño et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells

(2014) Heming Li et al.   Molecular Cancer

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(2014) Anastassios Philippou et al.   MOLECULAR MEDICINE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Insulin-like growth factor 1 receptor signaling induced by supraphysiological doses of IGF-1 in human peripheral blood lymphocytes

(2014) Sara Spaziani et al.   PROTEOMICS

Treatment of gastric cancer

(2014) Michele Orditura   WORLD JOURNAL OF GASTROENTEROLOGY

Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3β and ZEB2 in the BGC-823 gastric cancer cell line

(2014) HEMING LI et al.   Oncology Letters

A randomized, phase II study of the anti-insulin-like growth factor receptor type 1 (IGF-1R) monoclonal antibody robatumumab (SCH 717454) in patients with advanced colorectal cancer

(2014) Edward H. Lin et al.   Cancer Medicine

Prognostic value of insulin-like growth factor 1 and insulin-like growth factor binding protein 3 blood levels in breast cancer

(2013) H. Hartog et al.   BREAST

Action of GH on skeletal muscle function: molecular and metabolic mechanisms

(2013) Viral Chikani et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma

(2013) Laura Romero-Pérez et al.   MODERN PATHOLOGY

Tumor metastasis: moving new biological insights into the clinic

(2013) Liling Wan et al.   NATURE MEDICINE

Anticancer IGF1R classes take more knocks

(2013) Malini Guha   NATURE REVIEWS DRUG DISCOVERY

microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis

(2013) XUEGANG WANG et al.   ONCOLOGY REPORTS

IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations

(2013) Alejandro Vazquez-Martin et al.   Scientific Reports

Targeted drugs in combination with radiotherapy for the treatment of solid tumors: current state and future developments

(2013) Edgar Selzer et al.   Expert Review of Clinical Pharmacology

The descriptive epidemiology of female breast cancer: An international comparison of screening, incidence, survival and mortality

(2012) Danny R. Youlden et al.   Cancer Epidemiology

Resistance to Irreversible EGF Receptor Tyrosine Kinase Inhibitors through a Multistep Mechanism Involving the IGF1R Pathway

(2012) A. B. Cortot et al.   CANCER RESEARCH

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

Cadherins in collective cell migration of mesenchymal cells

(2012) Eric Theveneau et al.   CURRENT OPINION IN CELL BIOLOGY

TGF-β signaling and epithelial–mesenchymal transition in cancer progression

(2012) Yoko Katsuno et al.   CURRENT OPINION IN ONCOLOGY

Growth Hormone Doping in Sports: A Critical Review of Use and Detection Strategies

(2012) Gerhard P. Baumann   ENDOCRINE REVIEWS

Associations of insulin-like growth factor and insulin-like growth factor binding protein-3 with mortality in women with breast cancer

(2012) Catherine Duggan et al.   INTERNATIONAL JOURNAL OF CANCER

Zyxin Is a Transforming Growth Factor-β (TGF-β)/Smad3 Target Gene That Regulates Lung Cancer Cell Motility via Integrin α5β1

(2012) Nikica Mise et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF- -induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

(2012) S. Lamouille et al.   JOURNAL OF CELL SCIENCE

Early events in cell adhesion and polarity during epithelial-mesenchymal transition

(2012) R. Y.-J. Huang et al.   JOURNAL OF CELL SCIENCE

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

(2012) Chenfang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

IGF-1 and BRCA1 signalling pathways in familial cancer

(2012) Haim Werner et al.   LANCET ONCOLOGY

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MEMO1, a new IRS1-interacting protein, induces epithelial–mesenchymal transition in mammary epithelial cells

(2012) A V Sorokin et al.   ONCOGENE

Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer

(2012) C Dong et al.   ONCOGENE

E-Peptides Control Bioavailability of IGF-1

(2012) Marianne Smedegaard Hede et al.   PLoS One

Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1

(2012) K. Ohashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer stem cells and epithelial–mesenchymal transition: Concepts and molecular links

(2012) Christina Scheel et al.   SEMINARS IN CANCER BIOLOGY

mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways

(2011) P. Gulhati et al.   CANCER RESEARCH

Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness

(2011) J. Hong et al.   CANCER RESEARCH

Life at the Leading Edge

(2011) Anne J. Ridley   CELL

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition

(2011) Logan A Walsh et al.   Cell Communication and Signaling

A Phase I Pharmacokinetic and Pharmacodynamic Study of Dalotuzumab (MK-0646), an Anti-Insulin-like Growth Factor-1 Receptor Monoclonal Antibody, in Patients with Advanced Solid Tumors

(2011) F. Atzori et al.   CLINICAL CANCER RESEARCH

Targeting the insulin-like growth factor signaling pathway: figitumumab and other novel anticancer strategies

(2011) Timothy A Yap et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Functional Cooperation between Snail1 and Twist in the Regulation ofZEB1Expression during Epithelial to Mesenchymal Transition

(2011) Natàlia Dave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer

(2011) G. Lorenzatti et al.   JOURNAL OF CELL SCIENCE

Insulin-like growth factor 1 stimulation of androgen receptor activity requires β1A integrins

(2011) Aejaz Sayeed et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma

(2011) Yin-He Wang et al.   JOURNAL OF SURGICAL ONCOLOGY

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

(2011) Eleni Makrodouli et al.   Molecular Cancer

A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs

(2011) E L McKinsey et al.   ONCOGENE

EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin

(2011) Z-T Tong et al.   ONCOGENE

Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer

(2011) H Werner   ONCOGENE

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors

(2011) L. V. Sequist et al.   Science Translational Medicine

The insulin-like growth factor-I receptor as an oncogene

(2011) Haim Werner et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

The Insulin Receptor: A New Target for Cancer Therapy

(2011) Roberta Malaguarnera et al.   Frontiers in Endocrinology

MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells

(2010) Lu Jiang et al.   BIOCHEMICAL JOURNAL

Emergence of the Phosphoinositide 3-Kinase-Akt- Mammalian Target of Rapamycin Axis in Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition

(2010) Samy Lamouille et al.   CELLS TISSUES ORGANS

A Phase I Study of Weekly R1507, A Human Monoclonal Antibody Insulin-like Growth Factor-I Receptor Antagonist, in Patients with Advanced Solid Tumors

(2010) R. Kurzrock et al.   CLINICAL CANCER RESEARCH

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

Negative Regulation of EGFR-Vav2 Signaling Axis by Cbl Ubiquitin Ligase Controls EGF Receptor-mediated Epithelial Cell Adherens Junction Dynamics and Cell Migration

(2010) Lei Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Heterozygous Mutation of the Insulin-Like Growth Factor-I Receptor Causes Retention of the Nascent Protein in the Endoplasmic Reticulum and Results in Intrauterine and Postnatal Growth Retardation

(2010) Tillmann Wallborn et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Heterozygous Mutation within a Kinase-Conserved Motif of the Insulin-Like Growth Factor I Receptor Causes Intrauterine and Postnatal Growth Retardation

(2010) Tassilo Kruis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Small Is Beautiful: Insulin-Like Growth Factors and Their Role in Growth, Development, and Cancer

(2010) Robert G. Maki   JOURNAL OF CLINICAL ONCOLOGY

The Pathophysiology of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β in Normal and Malignant Mammary Epithelial Cells

(2010) Molly A. Taylor et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies

(2010)   LANCET ONCOLOGY

Differential regulation of insulin-like growth factor-I receptor gene expression by wild type and mutant androgen receptor in prostate cancer cells

(2010) Hagit Schayek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation

(2010) Jun Yu et al.   Molecular Cancer

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition

(2010) T Lin et al.   ONCOGENE

Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression

(2010) Kathryn E. Ware et al.   PLoS One

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Calorie restriction and cancer prevention: metabolic and molecular mechanisms

(2010) Valter D. Longo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Effect of Low-Intensity Aerobic Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Proteins in Healthy Men

(2010) Yuichiro Nishida et al.   International Journal of Endocrinology

The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women

(2009) Leanne M. Redman et al.   AGING CELL

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

Epithelial-mesenchymal transition in cancer development and its clinical significance

(2009) Masaaki Iwatsuki et al.   CANCER SCIENCE

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Expression Levels of Insulin-Like Growth Factor-1 and Multidrug Resistance-Associated Protein-1 Indicate Poor Prognosis in Patients with Gastric Cancer

(2009) Jie Ge et al.   DIGESTION

IGF-I abuse in sport: Current knowledge and future prospects for detection

(2009) Nishan Guha et al.   GROWTH HORMONE & IGF RESEARCH

Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts

(2009) Young Kim et al.   JOURNAL OF CELL BIOLOGY

Regulation of  4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition

(2009) X. Yang et al.   JOURNAL OF CELL SCIENCE

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans

(2008) Luigi Fontana et al.   AGING CELL

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

Insulin-like Growth Factor-I-Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2008) T. R. Graham et al.   CANCER RESEARCH

Identification of c-Cbl as a New Ligase for Insulin-like Growth Factor-I Receptor with Distinct Roles from Mdm2 in Receptor Ubiquitination and Endocytosis

(2008) B. Sehat et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Growth Hormone, Insulin-Like Growth Factors, and the Skeleton

(2008) Andrea Giustina et al.   ENDOCRINE REVIEWS

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins

(2008) Marta Guix et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin, the Insulin-Like Growth Factor Axis, and Mortality in Patients With Nonmetastatic Colorectal Cancer

(2008) Brian M. Wolpin et al.   JOURNAL OF CLINICAL ONCOLOGY

Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor

(2008) N. Herranz et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor

(2008) R. A. Jones et al.   MOLECULAR CANCER RESEARCH

Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: Lessons from the first clinical trials

(2008) J. Rodon et al.   MOLECULAR CANCER THERAPEUTICS

IGF signaling defects as causes of growth failure and IUGR

(2008) Jürgen Klammt et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Up-regulation of the Cbl family of ubiquitin ligases is involved in ATRA and bufalin-induced cell adhesion but not cell differentiation

(2007) Xiujuan Qu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS