A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs

The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells

(2015) Karen D. Cowden Dahl et al.   NEOPLASIA

MicroRNA-221-222 Regulate the Cell Cycle in Mast Cells

(2014) R. J. Mayoral et al.   JOURNAL OF IMMUNOLOGY

miR-99 Family of MicroRNAs Suppresses the Expression of Prostate-Specific Antigen and Prostate Cancer Cell Proliferation

(2011) Dandan Sun et al.   CANCER RESEARCH

FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing’s sarcoma cells

(2010) Liu Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression

(2010) Yi Ting et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity

(2010) J Zhang et al.   BRITISH JOURNAL OF CANCER

The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML

(2010) M Eyholzer et al.   BRITISH JOURNAL OF CANCER

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

MiR-222 Overexpression Confers Cell Migratory Advantages in Hepatocellular Carcinoma through Enhancing AKT Signaling

(2010) Q. W-L. Wong et al.   CLINICAL CANCER RESEARCH

The mTOR Pathway: A New Target in Cancer Therapy

(2010) L. Ciuffreda et al.   CURRENT CANCER DRUG TARGETS

Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future

(2010) Joseph A Ludwig   CURRENT OPINION IN ONCOLOGY

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

(2010) Gong-Hong Wei et al.   EMBO JOURNAL

An estrogen receptor α suppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples

(2010) Jianhua Xiong et al.   FEBS Journal

An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer

(2010) Jun Li et al.   GYNECOLOGIC ONCOLOGY

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2

(2010) Linhui Liang et al.   HEPATOLOGY

MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3

(2010) Li Huang et al.   INTERNATIONAL JOURNAL OF CANCER

MiR-125b targets BCL3 and suppresses ovarian cancer proliferation

(2010) Yi Guan et al.   INTERNATIONAL JOURNAL OF CANCER

microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia

(2010) Yoon-Chi Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

(2010) Chun-Zhi Zhang et al.   Molecular Cancer

A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer

(2010) Ankur K. Nagaraja et al.   MOLECULAR ENDOCRINOLOGY

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

(2010) Alexander Swarbrick et al.   NATURE MEDICINE

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein

(2010) J Xiong et al.   ONCOGENE

Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22

(2010) J B Patel et al.   ONCOGENE

Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer

(2010) S. Cairo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes

(2010) Xu-Bao Shi et al.   PROSTATE

Identification of the miR-106b 25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation

(2010) L. Poliseno et al.   Science Signaling

Ets Transcription Factors Control Epithelial Maturation and Transit and Crypt-Villus Morphogenesis in the Mammalian Intestine

(2009) Paul Jedlicka et al.   AMERICAN JOURNAL OF PATHOLOGY

MiRNAs and Cancer

(2009) Rosa Visone et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA-Based Therapeutics for Cancer

(2009) Vivien Wang et al.   BIODRUGS

MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation

(2009) Lei Shi et al.   BRAIN RESEARCH

Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

(2009) D Herrero-Martín et al.   BRITISH JOURNAL OF CANCER

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

MiR-125b Expression Affects the Proliferation and Apoptosis of Human Glioma Cells by Targeting Bmf

(2009) Hong-Fei Xia et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis

(2009) Christoph A Gebeshuber et al.   EMBO REPORTS

MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines

(2009) M.K. Muniyappa et al.   EUROPEAN JOURNAL OF CANCER

Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy

(2009) Brian J. Henson et al.   GENES CHROMOSOMES & CANCER

Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18β-olean-1,12-dien-30-oate in colon cancer cells

(2009) Sudhakar Chintharlapalli et al.   INTERNATIONAL JOURNAL OF CANCER

A natural antisense transcript, BOKAS, regulates the pro-apoptotic activity of human Bok

(2009) Zhang   INTERNATIONAL JOURNAL OF ONCOLOGY

Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

(2009) N Gefen et al.   LEUKEMIA

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNAs as potential cancer therapeutics

(2009) P Trang et al.   ONCOGENE

GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance

(2009) W Luo et al.   ONCOGENE

Regression of murine lung tumors by the let-7 microRNA

(2009) P Trang et al.   ONCOGENE

The Role of IGF-1R in Pediatric Malignancies

(2009) S. Y. Kim et al.   ONCOLOGIST

Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data

(2009) David L. Corcoran et al.   PLoS One

Upregulation of miR-23a∼27a∼24-2 Cluster Induces Caspase-Dependent and -Independent Apoptosis in Human Embryonic Kidney Cells

(2009) Ravindresh Chhabra et al.   PLoS One

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

(2009) G. H. S. Richter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell

(2009) G. Sotiropoulou et al.   RNA

Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection

(2008) C. C. Porter et al.   BLOOD

NF-κB–YY1–miR-29 Regulatory Circuitry in Skeletal Myogenesis and Rhabdomyosarcoma

(2008) Huating Wang et al.   CANCER CELL

MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin

(2008) Tao Liu et al.   CANCER LETTERS

The Promyelocytic Leukemia Zinc Finger-MicroRNA-221/-222 Pathway Controls Melanoma Progression through Multiple Oncogenic Mechanisms

(2008) F. Felicetti et al.   CANCER RESEARCH

The RSK factors of activating the Ras/MAPK signaling cascade

(2008) Audrey Carriere   Frontiers in Bioscience-Landmark

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis

(2008) N. S. Sokol et al.   GENES & DEVELOPMENT

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY

Human Cytomegalovirus Infection Alters the Expression of Cellular MicroRNA Species That Affect Its Replication

(2008) F.-Z. Wang et al.   JOURNAL OF VIROLOGY

IGF1 Is a Common Target Gene of Ewing's Sarcoma Fusion Proteins in Mesenchymal Progenitor Cells

(2008) Luisa Cironi et al.   PLoS One

Genome-Scale Validation of Deep-Sequencing Libraries

(2008) Dominic Schmidt et al.   PLoS One

The Inhibition of the Highly Expressed Mir-221 and Mir-222 Impairs the Growth of Prostate Carcinoma Xenografts in Mice

(2008) Neri Mercatelli et al.   PLoS One

Microsatellites as EWS/FLI response elements in Ewing's sarcoma

(2008) K. Gangwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA