Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer

IGF1R mutations as cause of SGA

(2011) J. Klammt et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin receptor and cancer

(2011) A. Belfiore et al.   ENDOCRINE-RELATED CANCER

Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies

(2011) Rachel Steuerman et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs

(2011) E L McKinsey et al.   ONCOGENE

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

MicroRNAs as therapeutic targets in cancer

(2011) S. Patrick Nana-Sinkam et al.   Translational Research

The insulin-like growth factor-I receptor as an oncogene

(2011) Haim Werner et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells

(2010) Lu Jiang et al.   BIOCHEMICAL JOURNAL

Basic and clinical significance of IGF-I-induced signatures in cancer

(2010) Haim Werner et al.   BMC Medicine

New plays in the p53 theater

(2010) Yael Aylon et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Targeting insulin-like growth factor 1 receptor in sarcomas

(2010) Katia Scotlandi et al.   CURRENT OPINION IN ONCOLOGY

 40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs

(2010) E. Ungewitter et al.   GENES & DEVELOPMENT

A Heterozygous Mutation of the Insulin-Like Growth Factor-I Receptor Causes Retention of the Nascent Protein in the Endoplasmic Reticulum and Results in Intrauterine and Postnatal Growth Retardation

(2010) Tillmann Wallborn et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Heterozygous Mutation within a Kinase-Conserved Motif of the Insulin-Like Growth Factor I Receptor Causes Intrauterine and Postnatal Growth Retardation

(2010) Tassilo Kruis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Small Is Beautiful: Insulin-Like Growth Factors and Their Role in Growth, Development, and Cancer

(2010) Robert G. Maki   JOURNAL OF CLINICAL ONCOLOGY

Differential regulation of insulin-like growth factor-I receptor gene expression by wild type and mutant androgen receptor in prostate cancer cells

(2010) Hagit Schayek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Serum microRNAs as non-invasive biomarkers for cancer

(2010) Jan C Brase et al.   Molecular Cancer

BRCA mutations in the management of breast cancer: the state of the art

(2010) Steven A. Narod   Nature Reviews Clinical Oncology

Apoptosis promotes early tumorigenesis

(2010) D Tang et al.   ONCOGENE

Identification of Insulin-Like Growth Factor-I Receptor (IGF-IR) Gene Promoter-Binding Proteins in Estrogen Receptor (ER)-Positive and ER-Depleted Breast Cancer Cells

(2010) Rive Sarfstein et al.   Cancers

Targeting the IGF1 axis in cancer proliferation

(2009) Ilan Bruchim et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Transcription factor E2F1 is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene

(2009) Hagit Schayek et al.   GROWTH HORMONE & IGF RESEARCH

Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression

(2009) Michael S. Wiesener et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

(2009) A Gualberto et al.   ONCOGENE

Nutrition, metabolic factors and cancer risk

(2008) Laure Dossus et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival

(2008) J. H. Law et al.   CANCER RESEARCH

Insulin-Like Growth Factor-I Regulates Krüppel-Like Factor-6 Gene Expression in a p53-Dependent Manner

(2008) Itay Bentov et al.   ENDOCRINOLOGY

Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer

(2008) John SP Yuen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

IGF and Insulin Receptor Signaling in Breast Cancer

(2008) Antonino Belfiore et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

IGF signaling defects as causes of growth failure and IUGR

(2008) Jürgen Klammt et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM