标题
Regulation of ferroptosis by lipid metabolism
作者
关键词
-
出版物
TRENDS IN CELL BIOLOGY
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-07-03
DOI
10.1016/j.tcb.2023.05.003
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Identification of essential sites of lipid peroxidation in ferroptosis
- (2023) A. Nikolai von Krusenstiern et al. Nature Chemical Biology
- Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
- (2023) Yusuke Hirata et al. CURRENT BIOLOGY
- Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2
- (2023) Yeping Wu et al. DEVELOPMENTAL CELL
- Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo
- (2023) John T. Randolph et al. Journal of Medicinal Chemistry
- Ferroptosis: A flexible constellation of related biochemical mechanisms
- (2023) Scott J. Dixon et al. MOLECULAR CELL
- TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids
- (2023) Alex Reed et al. Nature Chemical Biology
- Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo
- (2023) Yulia Y. Tyurina et al. Redox Biology
- PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis
- (2022) Hai-Liang Zhang et al. NATURE CELL BIOLOGY
- Positive feedback amplifies ferroptosis
- (2022) Jason Rodencal et al. NATURE CELL BIOLOGY
- Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
- (2022) Zhipeng Li et al. Nature Chemical Biology
- FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids
- (2022) Shaojie Cui et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers
- (2022) Pranavi Koppula et al. Nature Communications
- Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death
- (2022) Andrew M. Lamade et al. Redox Biology
- LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis
- (2022) Alex Reed et al. ACS Chemical Biology
- Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
- (2022) Brent R. Stockwell CELL
- Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death
- (2022) Luke A. Farmer et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A non-canonical vitamin K cycle is a potent ferroptosis suppressor
- (2022) Eikan Mishima et al. NATURE
- Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer
- (2022) Caterina Bartolacci et al. Nature Communications
- Sublethal cytochrome c release generates drug-tolerant persister cells
- (2022) Halime Kalkavan et al. CELL
- Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma
- (2022) Angela Criscuolo et al. Nature Communications
- Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity
- (2022) Marcos A. Perez et al. PLoS Genetics
- ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma
- (2022) Timothy D. Klasson et al. Cancer & Metabolism
- Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis
- (2022) Abdel A. Alli et al. CLINICAL IMMUNOLOGY
- The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
- (2022) Zhi Lin et al. Nature Communications
- CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
- (2021) Xingzhe Ma et al. Cell Metabolism
- A compendium of kinetic modulatory profiles identifies ferroptosis regulators
- (2021) Megan Conlon et al. Nature Chemical Biology
- Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
- (2021) Wan-Yang Sun et al. Nature Chemical Biology
- PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
- (2021) Xinxin Song et al. Cell Reports
- DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
- (2021) Chao Mao et al. NATURE
- Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1
- (2021) Alexander Beatty et al. Nature Communications
- Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects
- (2021) Emeline Dierge et al. Cell Metabolism
- iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4
- (2021) Delin Chen et al. Nature Communications
- Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway
- (2021) Sufang Shui et al. Redox Biology
- MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling
- (2021) Shan Xin et al. CELL DEATH AND DIFFERENTIATION
- Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity
- (2021) William J. Valentine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
- (2021) Ji Hyeon You et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death
- (2021) Omkar Zilka et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Characterization of a patient-derived variant of GPX4 for precision therapy
- (2021) Hengrui Liu et al. Nature Chemical Biology
- Enhanced lipid accumulation and metabolism are required for the differentiation and activation of tumor-associated macrophages
- (2020) Pan Su et al. CANCER RESEARCH
- Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis
- (2020) Yilong Zou et al. Nature Chemical Biology
- Lipid peroxidation and ferroptosis: The role of GSH and GPx4
- (2020) Fulvio Ursini et al. FREE RADICAL BIOLOGY AND MEDICINE
- Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles
- (2020) John K. Eaton et al. Nature Chemical Biology
- 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
- (2020) Arnaud Blomme et al. Nature Communications
- Dietary Lipids Induce Ferroptosis in Caenorhabditis elegans and Human Cancer Cells
- (2020) Marcos A. Perez et al. DEVELOPMENTAL CELL
- Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
- (2020) Mariluz Soula et al. Nature Chemical Biology
- Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
- (2020) Zeyad D Nassar et al. eLife
- Lymph protects metastasizing melanoma cells from ferroptosis
- (2020) Jessalyn M. Ubellacker et al. NATURE
- Plasticity of ether lipids promotes ferroptosis susceptibility and evasion
- (2020) Yilong Zou et al. NATURE
- Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture
- (2020) Michelle Riegman et al. NATURE CELL BIOLOGY
- PLA2G6 guards placental trophoblasts against ferroptotic injury
- (2020) Ofer Beharier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resolving the paradox of ferroptotic cell death: ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis
- (2020) Tamil S. Anthonymuthu et al. Redox Biology
- Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics
- (2020) Lohans Pedrera et al. CELL DEATH AND DIFFERENTIATION
- Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
- (2020) Bo Yan et al. MOLECULAR CELL
- Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer
- (2020) Ji-Yoon Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis
- (2020) Junmei Yi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer
- (2020) Corrin A. Wohlhieter et al. Cell Reports
- HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
- (2020) Youbo Zhao et al. Cell Reports
- GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis
- (2019) Giovanni C. Forcina et al. PROTEOMICS
- Ferroptosis as a target for protection against cardiomyopathy
- (2019) Xuexian Fang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
- (2019) Javier Garcia-Bermudez et al. NATURE
- Structure and Function of Δ9-Fatty Acid Desaturase
- (2019) Kohjiro Nagao et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway
- (2019) Bo Chu et al. NATURE CELL BIOLOGY
- Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death
- (2019) Lia Tesfay et al. CANCER RESEARCH
- A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
- (2019) Yilong Zou et al. Nature Communications
- The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
- (2019) Wen-Hsuan Yang et al. Cell Reports
- ESCRT-III–dependent membrane repair blocks ferroptosis
- (2019) Enyong Dai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Drugs Repurposed as Antiferroptosis Agents Suppress Organ Damage, Including AKI, by Functioning as Lipid Peroxyl Radical Scavengers
- (2019) Eikan Mishima et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- The chemical basis of ferroptosis
- (2019) Marcus Conrad et al. Nature Chemical Biology
- GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
- (2019) Vanessa A. N. Kraft et al. ACS Central Science
- Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis
- (2018) Michael M. Gaschler et al. ACS Chemical Biology
- Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
- (2018) Irina Ingold et al. CELL
- Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
- (2018) Behrouz Hassannia et al. JOURNAL OF CLINICAL INVESTIGATION
- Understanding the diversity of membrane lipid composition
- (2018) Takeshi Harayama et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
- (2018) Ron Shah et al. ACS Central Science
- Lipid storage and lipophagy regulates ferroptosis
- (2018) Yuansong Bai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy
- (2018) Lars Devisscher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine
- (2017) Ioannis Poursaitidis et al. Cell Reports
- On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death
- (2017) Omkar Zilka et al. ACS Central Science
- An essential role for functional lysosomes in ferroptosis of cancer cells
- (2016) S. Torii et al. BIOCHEMICAL JOURNAL
- Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
- (2016) Valerian E Kagan et al. Nature Chemical Biology
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
- (2016) Wan Seok Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
- (2015) Scott J. Dixon et al. ACS Chemical Biology
- CD36 Binds Oxidized Low Density Lipoprotein (LDL) in a Mechanism Dependent upon Fatty Acid Binding
- (2015) Anthony G. Jay et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More