Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo

Ferroptosis of tumour neutrophils causes immune suppression in cancer

(2022) Rina Kim et al.   NATURE

Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer

(2021) Ali Ghoochani et al.   CANCER RESEARCH

CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability

(2021) Xingzhe Ma et al.   Cell Metabolism

Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal

(2021) Wan-Yang Sun et al.   Nature Chemical Biology

Emerging mechanisms and targeted therapy of ferroptosis in cancer

(2021) Haiyan Wang et al.   MOLECULAR THERAPY

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

(2021) Alexander Beatty et al.   Nature Communications

Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

(2021) Shihao Xu et al.   IMMUNITY

The role of ferroptosis in melanoma

(2021) Ronan Talty et al.   Pigment Cell & Melanoma Research

Suppressive role of microRNA-130b-3p in ferroptosis in melanoma cells correlates with DKK1 inhibition and Nrf2-HO-1 pathway activation

(2021) Yangying Liao et al.   Human Cell

Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes

(2021) Sehwan Jang et al.   Redox Biology

The Art of War: Ferroptosis and Pancreatic Cancer

(2021) Jiao Liu et al.   Frontiers in Pharmacology

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

(2020) Alexandr A. Kapralov et al.   Nature Chemical Biology

Survival of patients with advanced metastatic melanoma: The impact of MAP kinase pathway inhibition and immune checkpoint inhibition - Update 2019

(2020) Selma Ugurel et al.   EUROPEAN JOURNAL OF CANCER

Polymorphonuclear myeloid-derived suppressor cells limit antigen cross-presentation by dendritic cells in cancer

(2020) Alessio Ugolini et al.   JCI Insight

Ferroptosis: a new unexpected chance to treat metastatic melanoma?

(2020) Mara Gagliardi et al.   CELL CYCLE

Lymph protects metastasizing melanoma cells from ferroptosis

(2020) Jessalyn M. Ubellacker et al.   NATURE

PLA2G6 guards placental trophoblasts against ferroptotic injury

(2020) Ofer Beharier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils

(2020) Michela Perego et al.   Science Translational Medicine

Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer

(2020) Taekyoung Kwak et al.   Cell Reports

Targeting Ferroptosis to Iron Out Cancer

(2019) Behrouz Hassannia et al.   CANCER CELL

Fatty acid transport protein 2 reprograms neutrophils in cancer

(2019) Filippo Veglia et al.   NATURE

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

Developing a xenograft human tumor model in immunocompetent mice

(2018) Matthew T. Basel et al.   CANCER LETTERS

Quantitative Profiling of Protein Carbonylations in Ferroptosis by an Aniline-Derived Probe

(2018) Ying Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

(2018) Michael M. Gaschler et al.   Nature Chemical Biology

Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?

(2018) D.A. Stoyanovsky et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

(2018) Haider H. Dar et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Differential effects of chlorinated and oxidized phospholipids in vascular tissue: implications for neointima formation

(2015) Fiona H. Greig et al.   CLINICAL SCIENCE

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

An improved SPE method for fractionation and identification of phospholipids

(2012) Alexander Fauland et al.   JOURNAL OF SEPARATION SCIENCE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Oxidized Phospholipid Species Promote in Vivo Differential Cx43 Phosphorylation and Vascular Smooth Muscle Cell Proliferation

(2009) Scott R. Johnstone et al.   AMERICAN JOURNAL OF PATHOLOGY

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

(2008) Wan Seok Yang et al.   CHEMISTRY & BIOLOGY