FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids

Three Phase Liquid Extraction (3PLE): A Simple, and Fast Method for Lipidomic Workflows

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FSP1 is a glutathione-independent ferroptosis suppressor

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

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Regulation of lipid peroxidation and ferroptosis in diverse species

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Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

(2018) Huizhong Feng et al.   PLOS BIOLOGY

Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart

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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

(2016) Bradley A. Carlson et al.   Redox Biology

Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

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Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin

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The role of lipoxygenases in pathophysiology; new insights and future perspectives

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Regulation of Ferroptotic Cancer Cell Death by GPX4

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Single-cell in situ imaging of palmitoylation in fatty-acylated proteins

(2014) Xinxin Gao et al.   Nature Protocols

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

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Serum levels of arachidonic acid metabolites change during prostate cancer progression

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A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

(2013) S. Zheng et al.   GENES & DEVELOPMENT

UAS domain of Ubxd8 and FAF1 polymerizes upon interaction with long-chain unsaturated fatty acids

(2013) Hyeonwoo Kim et al.   JOURNAL OF LIPID RESEARCH

Model Systems of Precursor Cellular Membranes: Long-Chain Alcohols Stabilize Spontaneously Formed Oleic Acid Vesicles

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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Fas-associated Factor 1 Is a Scaffold Protein That Promotes β-Transducin Repeat-containing Protein (β-TrCP)-mediated β-Catenin Ubiquitination and Degradation

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Exploring the Biology of Lipid Peroxidation-Derived Protein Carbonylation

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Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation

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Lipidomics reveals a remarkable diversity of lipids in human plasma,

(2010) Oswald Quehenberger et al.   JOURNAL OF LIPID RESEARCH