The role of microRNA-34 family in Alzheimer’s disease: A potential molecular link between neurodegeneration and metabolic disorders

Impact of diabetes mellitus and cardiometabolic syndrome on the risk of Alzheimer’s disease among postmenopausal women

(2021) Longjian Liu et al.   World Journal of Diabetes

Brain energy metabolism in intracerebroventricularly administered streptozotocin mouse model of Alzheimer’s disease: A 1H-[13C]-NMR study

(2021) Narayan D Soni et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?

(2021) Grazia Daniela Femminella et al.   Alzheimers Research & Therapy

Association Between Body Mass Index and Male Sperm Apoptosis and Apoptosis-Related Factors

(2021) Guangli Zhu et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Optimizing clinical phenotyping to better delineate the complex relationship between type 2 diabetes and Alzheimer’s disease

(2021) Angela J. Hanson et al.   CTS-Clinical and Translational Science

Alzheimer’s disease and its treatment by different approaches: A review

(2021) Sukriti Srivastava et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Brain insulin, insulin‐like growth factor 1 and glucagon‐like peptide 1 signalling in Alzheimer’s disease

(2021) Sergio T. Ferreira   JOURNAL OF NEUROENDOCRINOLOGY

Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer’s disease risk

(2021) Gloriia Novikova et al.   Molecular Neurodegeneration

Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics

(2021) B.C. Carlyle et al.   NEUROBIOLOGY OF AGING

Kainate Receptors and Synaptic Plasticity

(2021) Jithin D. Nair et al.   NEUROPHARMACOLOGY

Metabolic syndrome and the risk of late onset Alzheimer’s disease: An updated review and meta-analysis

(2021) Marco Zuin et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

The brain as an insulin-sensitive metabolic organ

(2021) Joshua L. Milstein et al.   Molecular Metabolism

Insulin Resistance and Diabetes Mellitus in Alzheimer’s Disease

(2021) Jesús Burillo et al.   Cells

Role of Receptor Protein Tyrosine Phosphatases (RPTPs) in Insulin Signaling and Secretion

(2021) Julio Sevillano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In Silico Analysis to Link Insulin Resistance, Obesity and Ageing with Alzheimer’s Disease

(2021) Priyanka Sarkar et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Metabolic Syndrome Is Associated With Poor Cognition: A Population-Based Study of 70-Year-Old Adults Without Dementia

(2021) Anna Marseglia et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Hepatocyte miR-34a is a key regulator in the development and progression of non-alcoholic fatty liver disease

(2021) Yanyong Xu et al.   Molecular Metabolism

Neurodevelopment regulators miR-137 and miR-34 family as biomarkers for early and adult onset schizophrenia

(2021) Bao-Yu Chen et al.   npj Schizophrenia

Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer’s Disease

(2020) Zhongli Shi et al.   AGING CELL

A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles

(2020) Jian-Guo Li et al.   Molecular Neurodegeneration

Brain microRNAs dysregulation: implication for missplicing and abnormal post-translational modifications of tau protein in Alzheimer’s disease and related tauopathies

(2020) Maryam Bazrgar et al.   PHARMACOLOGICAL RESEARCH

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells

(2020) Elizabeth M. McNeill et al.   Nature Communications

Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework

(2020) Alexios-Fotios A. Mentis et al.   MOLECULAR PSYCHIATRY

Oligomerization and Conformational Change Turn Monomeric β-Amyloid and Tau Proteins Toxic: Their Role in Alzheimer’s Pathogenesis

(2020) Botond Penke et al.   MOLECULES

Role of microRNAs in neurodegeneration induced by environmental neurotoxicants and aging

(2020) Tanisha Singh et al.   AGEING RESEARCH REVIEWS

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease

(2020) Tiantian Guo et al.   Molecular Neurodegeneration

Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy

(2020) Marina Buciuc et al.   NEUROLOGY

miR-34a Regulates the Activity of HIF-1a and P53 Signaling Pathways by Promoting GLUT1 in Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus) Under Hypoxia Stress

(2020) Jun Qiang et al.   Frontiers in Physiology

Positive association of a Sirt1 variant and parameters of oxidative stress on Alzheimer’s disease

(2020) Daniela Camporez et al.   NEUROLOGICAL SCIENCES

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

microRNA-34a (miRNA-34a) Mediated Down-Regulation of the Post-synaptic Cytoskeletal Element SHANK3 in Sporadic Alzheimer's Disease (AD)

(2019) Yuhai Zhao et al.   Frontiers in Neurology

MiR-34 and MiR-200: Regulator of Cell Fate Plasticity and Neural Development

(2019) Abhishek Jauhari et al.   NEUROMOLECULAR MEDICINE

The Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer’s Dementia

(2019) Jaume Folch et al.   Frontiers in Aging Neuroscience

Diabetes mellitus and risks of cognitive impairment and dementia: A systematic review and meta-analysis of 144 prospective studies

(2019) Mei Xue et al.   AGEING RESEARCH REVIEWS

Over-expression of miR-34c leads to early-life visceral fat accumulation and insulin resistance

(2019) Philip H. Jones et al.   Scientific Reports

Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer’s disease

(2019) Soheil Madadi et al.   Cell and Bioscience

Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases

(2019) Pedro Gomes et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Evidence for brain glucose dysregulation in Alzheimer's disease

(2018) Yang An et al.   Alzheimers & Dementia

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Treating cancer with microRNA replacement therapy: A literature review

(2018) Nayer Hosseinahli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA expression data analysis to identify key miRNAs associated with Alzheimer's disease

(2018) Jing Chen et al.   JOURNAL OF GENE MEDICINE

Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention

(2018) Long Wu et al.   JOURNAL OF NEUROSCIENCE

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Insulin-mediated synaptic plasticity in the CNS: Anatomical, functional and temporal contexts

(2018) Carrie R. Ferrario et al.   NEUROPHARMACOLOGY

miR-34a deficiency in APP/PS1 mice promotes cognitive function by increasing synaptic plasticity via AMPA and NMDA receptors

(2018) Yuelong Xu et al.   NEUROSCIENCE LETTERS

Left lateralized cerebral glucose metabolism declines in amyloid-β positive persons with mild cognitive impairment

(2018) Christopher M. Weise et al.   NeuroImage-Clinical

The Association of Plasma Levels of Mir-34A and Mir-149 with Obesity and Insulin Resistance in Obese Children and Adolescents

(2018) F Ahmadpour   Acta Endocrinologica-Bucharest

RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer’s Associated Cognitive Deficits

(2018) Dongdong Zhao et al.   BIOLOGICAL PSYCHIATRY

Subcutaneous Administration of Liraglutide Ameliorates Alzheimer-Associated Tau Hyperphosphorylation in Rats with Type 2 Diabetes1

(2018) Yan Yang et al.   JOURNAL OF ALZHEIMERS DISEASE

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

(2018) Jacob O'Brien et al.   Frontiers in Endocrinology

Aging-Related Changes in Cognition and Cortical Integrity are Associated With Serum Expression of Candidate MicroRNAs for Alzheimer Disease

(2018) Ines Maldonado-Lasuncion et al.   CEREBRAL CORTEX

Etiology of Metabolic Syndrome and Dietary Intervention

(2018) Hang Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-34a in Neurophysiology and Neuropathology

(2018) Christelle En Lin Chua et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development

(2018) Tomasz J. Nowakowski et al.   NATURE NEUROSCIENCE

Amyloid β oligomers (AβOs) in Alzheimer’s disease

(2017) Barbara Mroczko et al.   JOURNAL OF NEURAL TRANSMISSION

miR-34a knockout attenuates cognitive deficits in APP/PS1 mice through inhibition of the amyloidogenic processing of APP

(2017) Chongdong Jian et al.   LIFE SCIENCES

Regulation of miR-34 Family in Neuronal Development

(2017) Abhishek Jauhari et al.   MOLECULAR NEUROBIOLOGY

An integrated expression atlas of miRNAs and their promoters in human and mouse

(2017) Derek de Rie et al.   NATURE BIOTECHNOLOGY

Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony

(2017) Stefania Forner et al.   TRENDS IN NEUROSCIENCES

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors

(2016) Muhammad S. Beg et al.   INVESTIGATIONAL NEW DRUGS

Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults

(2016) Samantha L. Gardener et al.   JOURNAL OF ALZHEIMERS DISEASE

Deregulation of miRNA-181c potentially contributes to the pathogenesis of AD by targeting collapsin response mediator protein 2 in mice

(2016) Huimin Zhou et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

(2016) Michael S. Bonkowski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ApoE2 and Alzheimer′s disease: time to take a closer look

(2016) Liqin Zhao et al.   Neural Regeneration Research

Sirtuins and nonalcoholic fatty liver disease

(2016) Fatiha Nassir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss

(2016) J. Di et al.   Scientific Reports

Controlling SIRT1 expression by microRNAs in health and metabolic disease

(2016) Jiyoung Lee et al.   Aging-US

Molecular Mechanisms of Amyloid Oligomers Toxicity

(2016) Rakez Kayed et al.   JOURNAL OF ALZHEIMERS DISEASE

Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model

(2015) Aaron N Long et al.   BMC Neurology

Targeting Insulin Signaling for the Treatment of Alzheimer's Disease

(2015) Yanxing Chen et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Critical role of the miR-200 family in regulating differentiation and proliferation of neurons

(2015) Ankita Pandey et al.   JOURNAL OF NEUROCHEMISTRY

Regulation of Neuronal Cell Cycle and Apoptosis by miR-34a

(2015) Prashant Kumar Modi et al.   MOLECULAR AND CELLULAR BIOLOGY

Are microRNAs the Molecular Link Between Metabolic Syndrome and Alzheimer’s Disease?

(2015) Juan F. Codocedo et al.   MOLECULAR NEUROBIOLOGY

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

miR-34a regulates cell proliferation, morphology and function of newborn neurons resulting in improved behavioural outcomes

(2015) C Mollinari et al.   Cell Death & Disease

Secreted miR-34a in astrocytic shedding vesicles enhanced the vulnerability of dopaminergic neurons to neurotoxins by targeting Bcl-2

(2015) Susu Mao et al.   Protein & Cell

miR-34 and p53: New Insights into a Complex Functional Relationship

(2015) Francisco Navarro et al.   PLoS One

Identifying microRNA targets in different gene regions

(2014) Wenlong Xu et al.   BMC BIOINFORMATICS

Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice

(2014) Yanxing Chen et al.   EXPERIMENTAL NEUROLOGY

MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins

(2014) Ana L. Morgado et al.   MOLECULAR NEUROBIOLOGY

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

(2014) Meredith A. Chabrier et al.   NEUROBIOLOGY OF DISEASE

Apoptosis in Alzheimer’s Disease: An Understanding of the Physiology, Pathology and Therapeutic Avenues

(2014) M. Obulesu et al.   NEUROCHEMICAL RESEARCH

Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes

(2014) Soyon Hong et al.   NEURON

Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

(2014) J. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The p53/miR-34 axis in development and disease

(2014) M. Rokavec et al.   Journal of Molecular Cell Biology

Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update

(2014) Surjyadipta Bhattacharjee et al.   Frontiers in Aging Neuroscience

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Increased microRNA-34c abundance in Alzheimer's disease circulating blood plasma

(2014) Shephali Bhatnagar et al.   Frontiers in Molecular Neuroscience

MicroRNAs as Mediators of the Ageing Process

(2014) Lorna Harries   Genes

Elevated microRNA-34a in obesity reduces NAD+levels and SIRT1 activity by directly targeting NAMPT

(2013) Sung-E Choi et al.   AGING CELL

Criteria for mild cognitive impairment due to alzheimer's disease in the community

(2013) Ronald C. Petersen et al.   ANNALS OF NEUROLOGY

Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA

(2013) Mingyi Xie et al.   CELL

A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis

(2013) M Kracikova et al.   CELL DEATH AND DIFFERENTIATION

Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line

(2013) Peter N. Alexandrov et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Changes in Brain Function Occur Years before the Onset of Cognitive Impairment

(2013) L. L. Beason-Held et al.   JOURNAL OF NEUROSCIENCE

Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice

(2013) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Temporal synchrony and gamma-to-theta power conversion in the dendrites of CA1 pyramidal neurons

(2013) Sachin P Vaidya et al.   NATURE NEUROSCIENCE

Tau phosphorylation affects its axonal transport and degradation

(2013) Teresa Rodríguez-Martín et al.   NEUROBIOLOGY OF AGING

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid

(2013) Mareike Müller et al.   NEUROBIOLOGY OF AGING

Dysfunctional synapse in Alzheimer's disease – A focus on NMDA receptors

(2013) Sandra I. Mota et al.   NEUROPHARMACOLOGY

Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a

(2013) Yuhai Zhao et al.   NEUROREPORT

Senescence and aging: the critical roles of p53

(2013) A Rufini et al.   ONCOGENE

MicroRNA miR-324-3p Induces Promoter-Mediated Expression of RelA Gene

(2013) Ashutosh Dharap et al.   PLoS One

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Surf the Post-translational Modification Network of p53 Regulation

(2012) Bo Gu et al.   International Journal of Biological Sciences

MicroRNAs and their roles in aging

(2012) T. Smith-Vikos et al.   JOURNAL OF CELL SCIENCE

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

(2012) Rui E. Castro et al.   JOURNAL OF HEPATOLOGY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model

(2012) J. Brouillette et al.   JOURNAL OF NEUROSCIENCE

Loss of Intranetwork and Internetwork Resting State Functional Connections with Alzheimer's Disease Progression

(2012) M. R. Brier et al.   JOURNAL OF NEUROSCIENCE

Insulin in the Brain: Sources, Localization and Functions

(2012) Rasoul Ghasemi et al.   MOLECULAR NEUROBIOLOGY

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-34a Expression, Cell Cycle Arrest and Cell Death of Malignant Mesothelioma Cells upon Treatment with Radiation, Docetaxel or Combination Treatment

(2012) Taha Ghawanmeh et al.   ONCOLOGY

MiR-34a Represses Numbl in Murine Neural Progenitor Cells and Antagonizes Neuronal Differentiation

(2012) Sarah K. Fineberg et al.   PLoS One

MicroRNA Regulation of the Synaptic Plasticity-Related Gene Arc

(2012) Karin Wibrand et al.   PLoS One

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor  -Klotho

(2012) T. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-34a modulates genes involved in cellular motility and oxidative phosphorylation in neural precursors derived from human umbilical cord mesenchymal stem cells

(2011) Shing-Jyh Chang et al.   BMC Medical Genomics

Aβ Oligomer-Induced Synapse Degeneration in Alzheimer’s Disease

(2011) Kyle C. Wilcox et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

microRNA-34c is a novel target to treat dementias

(2011) Athanasios Zovoilis et al.   EMBO JOURNAL

The rno-miR-34 family is upregulated and targets ACSL1 in dimethylnitrosamine-induced hepatic fibrosis in rats

(2011) Wei-Qing Li et al.   FEBS Journal

Metabolic regulation by p53

(2011) Oliver D. K. Maddocks et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes

(2011) X.-Y. Bai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Role of p53 in Neurodegenerative Diseases

(2011) J. Robert Chang et al.   Neurodegenerative Diseases

Circulating MicroRNAs in Patients with Chronic Hepatitis C and Non-Alcoholic Fatty Liver Disease

(2011) Silvia Cermelli et al.   PLoS One

miR-34a Regulates Mouse Neural Stem Cell Differentiation

(2011) Márcia M. Aranha et al.   PLoS One

MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma

(2011) Pasqualino de Antonellis et al.   PLoS One

microRNA-34a regulates neurite outgrowth, spinal morphology, and function

(2011) M. Agostini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

(2010) Lei Kong et al.   ACTA DIABETOLOGICA

AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

(2010) Valérie Vingtdeux et al.   ACTA NEUROPATHOLOGICA

p53, Oxidative Stress, and Aging

(2010) Dongping Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Progressive accumulation of amyloid-β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins

(2010) Emiley Pham et al.   FEBS Journal

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Pathway Involving Farnesoid X Receptor and Small Heterodimer Partner Positively Regulates Hepatic Sirtuin 1 Levels via MicroRNA-34a Inhibition

(2010) Jiyoung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53

(2010) Lan Wang et al.   MOLECULAR BIOLOGY REPORTS

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

(2010) Jun Gao et al.   NATURE

Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study

(2010) T. Matsuzaki et al.   NEUROLOGY

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

(2010) J.-S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relationship between the diagnostic components of metabolic syndrome (MS) and cognition by ApoE genotype in the elderly

(2009) Kang Soo Lee et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation

(2009) Xiaoying Wang et al.   BRAIN RESEARCH BULLETIN

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

(2009) Jongsook Kim Kemper et al.   Cell Metabolism

The multiple functions of Numb

(2009) Alberto Gulino et al.   EXPERIMENTAL CELL RESEARCH

Differential expression of microRNAs in mouse liver under aberrant energy metabolic status

(2009) Shengjie Li et al.   JOURNAL OF LIPID RESEARCH

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice

(2009) Enpeng Zhao et al.   MAMMALIAN GENOME

Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain

(2009) Na Li et al.   NEUROBIOLOGY OF AGING

MicroRNAs Potentiate Neural Development

(2009) Sarah K. Fineberg et al.   NEURON

O3-02-07: Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

(2008) Jill C. Richardson et al.   Alzheimers & Dementia

Co-Localization of Amyloid Beta and Tau Pathology in Alzheimer's Disease Synaptosomes

(2008) Jeffrey A. Fein et al.   AMERICAN JOURNAL OF PATHOLOGY

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

(2008) Onpan Cheung et al.   HEPATOLOGY

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

(2008) K. A. Cole et al.   MOLECULAR CANCER RESEARCH

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

(2008) J. J. Forman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA expression in the adult mouse central nervous system

(2008) M. Bak et al.   RNA