标题
Alzheimer’s disease and its treatment by different approaches: A review
作者
关键词
Acetylcholinesterase, Alzheimer’s disease, Amyloid beta protein, Biomarker, Clinical trial, Molecular target, Stem cell, Nanoparticle
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 216, Issue -, Pages 113320
出版商
Elsevier BV
发表日期
2021-02-23
DOI
10.1016/j.ejmech.2021.113320
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Application of Iron Oxide Nanoparticles in the Diagnosis and Treatment of Neurodegenerative Diseases With Emphasis on Alzheimer’s Disease
- (2020) Shen Luo et al. Frontiers in Cellular Neuroscience
- Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery
- (2020) Stamatia Laidou et al. Redox Biology
- A hallmark of phospholamban functional divergence is located in the N-terminal phosphorylation domain
- (2020) Eli Fernández-de Gortari et al. Computational and Structural Biotechnology Journal
- Fluorescent Biosensor of CDK5 Kinase Activity in Glioblastoma Cell Extracts and Living Cells
- (2020) Marion Peyressatre et al. Biotechnology Journal
- Memantine nanoemulsion: a new approach to treat Alzheimer’s disease
- (2020) Atinderpal Kaur et al. JOURNAL OF MICROENCAPSULATION
- Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases
- (2020) Yu-Han Chung et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Noncoding RNA MaIL1 is an integral component of the TLR4–TRIF pathway
- (2020) Marina Aznaourova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacotherapy of Alzheimer’s Disease: Seeking Clarity in a Time of Uncertainty
- (2020) Nurul Husna Ibrahim et al. Frontiers in Pharmacology
- Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer’s disease
- (2020) Jingshu Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease
- (2020) Emyr Lloyd-Evans et al. Essays in Biochemistry
- New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation
- (2020) Martina Bortolami et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- “STRESSED OUT”: The Role of FUS and TDP-43 in Amyotrophic lateral sclerosis
- (2020) Yagiz Alp Aksoy et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Muramyl dipeptide-mediated immunomodulation on monocyte subsets exerts therapeutic effects in a mouse model of Alzheimer’s disease
- (2020) Adham Fani Maleki et al. Journal of Neuroinflammation
- Amburana cearensis: Pharmacological and Neuroprotective Effects of Its Compounds
- (2020) Juliana Helena Castro e Silva et al. MOLECULES
- The Effects of Alpha-Linolenic Acid on the Secretory Activity of Astrocytes and β Amyloid-Associated Neurodegeneration in Differentiated SH-SY5Y Cells: Alpha-Linolenic Acid Protects the SH-SY5Y cells against β Amyloid Toxicity
- (2020) Anna Litwiniuk et al. Oxidative Medicine and Cellular Longevity
- Glia Crosstalk in Neuroinflammatory Diseases
- (2020) Ada Bernaus et al. Frontiers in Cellular Neuroscience
- Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons
- (2020) Manoj Kumar et al. Stem Cell Reports
- Quantitative patterns of motor cortex proteinopathy across ALS genotypes
- (2020) Matthew Nolan et al. Acta Neuropathologica Communications
- GSK3‐ARC/Arg3.1 and GSK3‐Wnt signaling axes trigger amyloid‐β accumulation and neuroinflammation in middle‐aged Shugoshin 1 mice
- (2020) Chinthalapally V. Rao et al. AGING CELL
- Facile Impedimetric Analysis of Neuronal Exosome Markers in Parkinson’s Disease Diagnostics
- (2020) Ying Fu et al. ANALYTICAL CHEMISTRY
- Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants
- (2020) Lalitha Venkataraman et al. BMC NEUROSCIENCE
- Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration
- (2020) John L Robinson et al. BRAIN
- Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule—Purkinje Neuron Synaptic Strength
- (2020) Aleksandar Arsović et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Protein Biomarkers for the Diagnosis of Alzheimer’s Disease at Different Stages of Neurodegeneration
- (2020) Mar Pérez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A Randomized Clinical Trial of Greek High Phenolic Early Harvest Extra Virgin Olive Oil in Mild Cognitive Impairment: The MICOIL Pilot Study
- (2020) Magda Tsolaki et al. JOURNAL OF ALZHEIMERS DISEASE
- Design, Synthesis, and Structure–Activity Relationships of Thiazole Analogs as Anticholinesterase Agents for Alzheimer’s Disease
- (2020) Begüm Nurpelin Sağlık et al. MOLECULES
- Glutamate-responsive translation of dendritic GSK3β mRNA triggers a cycle for amplification of reactivated preexisting GSK3β that is indispensable for tau hyperphosphorylation
- (2020) Toru Tanaka et al. NEUROCHEMISTRY INTERNATIONAL
- Hippocampal subfield pathologic burden in Lewy body diseases vs . Alzheimer’s disease
- (2020) D. G. Coughlin et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS
- (2020) In Jun Yeo et al. Cell Death & Disease
- Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology
- (2020) David X. Thomas et al. Scientific Reports
- Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington’s disease transgenic mouse
- (2020) Li Niu et al. Cell and Bioscience
- Teaching the basics of repurposing mitochondria-targeted drugs: From Parkinson's disease to cancer and back to Parkinson's disease
- (2020) Balaraman Kalyanaraman Redox Biology
- Association of rare variants in neurodegenerative genes with familial Alzheimer’s disease
- (2020) Weiwei Zhang et al. Annals of Clinical and Translational Neurology
- Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study
- (2020) Satoshi Muraoka et al. Cells
- Phytochemical delivery through nanocarriers: a review
- (2020) Razi Ahmad et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Changes in subunit composition of NMDA receptors in animal models of schizophrenia by repeated administration of methamphetamine
- (2020) Matsuhiko Oka et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Treatment Combinations for Alzheimer’s Disease: Current And Future Pharmacotherapy Options
- (2019) Jeffrey L. Cummings et al. JOURNAL OF ALZHEIMERS DISEASE
- Expression Changes of NMDA and AMPA Receptor Subunits in the Hippocampus in rats with Diabetes Induced by Streptozotocin Coupled with Memory Impairment
- (2019) Xiao-Peng Wang et al. NEUROCHEMICAL RESEARCH
- New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease
- (2019) Nicolas Sergeant et al. NEUROBIOLOGY OF DISEASE
- Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
- (2019) D. Allan Butterfield et al. NATURE REVIEWS NEUROSCIENCE
- Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease
- (2019) Lei Zhang et al. BIOMATERIALS
- Magnetite/Ceria Nanoparticle Assemblies for Extracorporeal Cleansing of Amyloid‐β in Alzheimer's Disease
- (2019) Dokyoon Kim et al. ADVANCED MATERIALS
- Nanoparticle technology and stem cell therapy team up against neurodegenerative disorders
- (2019) Caroline Vissers et al. ADVANCED DRUG DELIVERY REVIEWS
- Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation
- (2019) Alberto Catanese et al. Autophagy
- Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities
- (2019) Judit M. Perez Ortiz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Alzheimer disease and aducanumab: adjusting our approach
- (2019) Dennis J. Selkoe Nature Reviews Neurology
- Binding between Prion Protein and Aβ Oligomers Contributes to the Pathogenesis of Alzheimer’s Disease
- (2019) Chang Kong et al. VIROLOGICA SINICA
- PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis
- (2019) Chaojun Yan et al. Autophagy
- Nanoparticle formulations in the diagnosis and therapy of Alzheimer's disease
- (2019) Jyoti Gupta et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Refolding of thermally denatured cholesterol oxidases by magnetic nanoparticles
- (2019) Shubhrima Ghosh et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases
- (2019) Roberta Cascella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Evaluation of urinary 8-hydroxy-2-deoxyguanosine level in experimental Alzheimer’s disease: Impact of carvacrol nanoparticles
- (2019) Dalia Medhat et al. MOLECULAR BIOLOGY REPORTS
- Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer’s Disease
- (2019) Mar Cuadrado-Tejedor et al. Frontiers in Aging Neuroscience
- 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer’s Signaling in Human Nerve Cells
- (2019) Zhibin Liang et al. ACS Chemical Neuroscience
- Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update
- (2019) Giovanna Cenini et al. Frontiers in Pharmacology
- Potent Activity of Composite Cyclin Dependent Kinase Inhibition against Hepatocellular Carcinoma
- (2019) Yu-Yun Shao et al. Cancers
- Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis
- (2019) Nashwah Ismail et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nanoparticle-mediated approaches for Alzheimer’s disease pathogenesis, diagnosis, and therapeutics
- (2019) Sajini D. Hettiarachchi et al. JOURNAL OF CONTROLLED RELEASE
- Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
- (2019) Maya Koronyo-Hamaoui et al. BRAIN
- “Tau Protein Targeting Via Radioiodinated Azure A For Brain Theranostics: Radiolabeling, Molecular Docking, in vitro And in vivo Biological Evaluation”
- (2019) Gamal Abdelaziz et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Targeting Fyn Kinase in Alzheimer’s Disease
- (2018) Haakon B. Nygaard BIOLOGICAL PSYCHIATRY
- Transplanted neural-like cells improve memory and Alzheimer-like pathology in a rat model
- (2018) Elham Hoveizi et al. CYTOTHERAPY
- Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer’s disease
- (2018) Govindarajan Karthivashan et al. DRUG DELIVERY
- Presenilins as Drug Targets for Alzheimer’s Disease—Recent Insights from Cell Biology and Electrophysiology as Novel Opportunities in Drug Development
- (2018) R. Duncan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Memantine for the Treatment of Dementia: A Review on its Current and Future Applications
- (2018) Jaume Folch et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease
- (2018) Russell H. Swerdlow JOURNAL OF ALZHEIMERS DISEASE
- Oleocanthal-rich extra-virgin olive oil enhances donepezil effect by reducing amyloid-β load and related toxicity in a mouse model of Alzheimer’s disease
- (2018) Yazan S. Batarseh et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Regulation of Pleiotrophin and Fyn in the striatum of rats undergoing L-DOPA-induced dyskinesia
- (2018) Gimena Gomez et al. NEUROSCIENCE LETTERS
- Reactive astrocytes in Alzheimer’s disease: A double-edged sword
- (2018) Heejung Chun et al. NEUROSCIENCE RESEARCH
- Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease
- (2018) Michael F. Egan et al. NEW ENGLAND JOURNAL OF MEDICINE
- A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease
- (2018) Estela Area-Gomez et al. Cell Death & Disease
- Recent Advances: Decoding Alzheimer’s Disease With Stem Cells
- (2018) Yi Fang et al. Frontiers in Aging Neuroscience
- Alzheimer’s Disease (AD) therapeutics - 1: Repeated clinical failures continue to question the amyloid hypothesis of AD and the current understanding of AD causality
- (2018) Kevin Mullane et al. BIOCHEMICAL PHARMACOLOGY
- Calcium signaling in Alzheimer's disease & therapies
- (2018) Benjamin Chun-Kit Tong et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer’s disease
- (2018) Gary P. Morris et al. ACTA NEUROPATHOLOGICA
- The exploration of novel Alzheimer’s therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches
- (2018) Mubashir Hassan et al. BIOMEDICINE & PHARMACOTHERAPY
- A promising, novel, and unique BACE1 inhibitor emerges in the quest to prevent Alzheimer's disease
- (2018) Justyna A Dobrowolska Zakaria et al. EMBO Molecular Medicine
- Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer’s Disease
- (2018) Ahmed Morsy et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease
- (2018) Mikael Marttinen et al. Frontiers in Neuroscience
- A review on tacrine-based scaffolds as multi-target drugs (MTDLs) for Alzheimer's disease
- (2017) Bilqees Sameem et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Alzheimer's disease
- (2017) C. A. Lane et al. EUROPEAN JOURNAL OF NEUROLOGY
- Wheat germ agglutinin-conjugated liposomes incorporated with cardiolipin to improve neuronal survival in Alzheimer’s disease treatment
- (2017) Yung-Chih Kuo et al. International Journal of Nanomedicine
- Anti-Alzheimer's potential of berberine using surface decorated multi-walled carbon nanotubes: A preclinical evidence
- (2017) Shikha Lohan et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Iminodiacetic acid-conjugated nanoparticles as a bifunctional modulator against Zn 2+ -mediated amyloid β-protein aggregation and cytotoxicity
- (2017) Hongchen Liu et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Synergistic effects of negatively charged hydrophobic nanoparticles and (−)-epigallocatechin-3-gallate on inhibiting amyloid β-protein aggregation
- (2017) Hongchen Liu et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Nerve growth factor-loaded heparinized cationic solid lipid nanoparticles for regulating membrane charge of induced pluripotent stem cells during differentiation
- (2017) Yung-Chih Kuo et al. Materials Science & Engineering C-Materials for Biological Applications
- Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease
- (2017) Joana Loureiro et al. MOLECULES
- The effects of gold nanoparticles functionalized with ß -amyloid specific peptides on an in vitro model of blood–brain barrier
- (2017) J. Ruff et al. Nanomedicine-Nanotechnology Biology and Medicine
- Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support
- (2017) Samuel E. Marsh et al. NEUROCHEMISTRY INTERNATIONAL
- Multifunctional liposomes interact with Abeta in human biological fluids: Therapeutic implications for Alzheimer's disease
- (2017) Elisa Conti et al. NEUROCHEMISTRY INTERNATIONAL
- Edible Bird’s Nest Prevents Menopause-Related Memory and Cognitive Decline in Rats via Increased Hippocampal Sirtuin-1 Expression
- (2017) Zhiping Hou et al. Oxidative Medicine and Cellular Longevity
- Xanthoceraside modulates NR2B-containing NMDA receptors at synapses and rescues learning-memory deficits in APP/PS1 transgenic mice
- (2017) Lin Zhu et al. PSYCHOPHARMACOLOGY
- Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats
- (2017) Clémence Disdier et al. Scientific Reports
- Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease
- (2016) Hyek Jin Kwon et al. ACS Nano
- Gold nanoparticle-capped mesoporous silica-based H 2 O 2 -responsive controlled release system for Alzheimer’s disease treatment
- (2016) Licong Yang et al. Acta Biomaterialia
- Brain-targeted co-delivery of therapeutic gene and peptide by multifunctional nanoparticles in Alzheimer's disease mice
- (2016) Yang Liu et al. BIOMATERIALS
- Conformation of ryanodine receptor-2 gates store-operated calcium entry in rat pulmonary arterial myocytes
- (2016) Amanda H.Y. Lin et al. CARDIOVASCULAR RESEARCH
- Resveratrol Improves Cognitive Impairment by Regulating Apoptosis and Synaptic Plasticity in Streptozotocin-Induced Diabetic Rats
- (2016) Zhiyan Tian et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer’s disease treatment
- (2016) Joana A. Loureiro et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- New transgenic ALS/FTD models on the rat-walk
- (2016) Judith Stegmüller et al. JOURNAL OF NEUROCHEMISTRY
- Alzheimer's disease: An overview of amyloid beta dependent pathogenesis and its therapeutic implications along with in silico approaches emphasizing the role of natural products
- (2016) Manika Awasthi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Alzheimer's disease
- (2016) Philip Scheltens et al. LANCET
- The miR-15/107 Family of microRNA Genes Regulates CDK5R1/p35 with Implications for Alzheimer’s Disease Pathogenesis
- (2016) Silvia Moncini et al. MOLECULAR NEUROBIOLOGY
- Anthocyanin-Loaded PEG-Gold Nanoparticles Enhanced the Neuroprotection of Anthocyanins in an Aβ1–42 Mouse Model of Alzheimer’s Disease
- (2016) Tahir Ali et al. MOLECULAR NEUROBIOLOGY
- Exosomes in Alzheimer's disease
- (2016) Tarja Malm et al. NEUROCHEMISTRY INTERNATIONAL
- IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses
- (2016) Neta Gazit et al. NEURON
- Stem Cell Therapy: A Prospective Treatment for Alzheimer's Disease
- (2016) Ji Han Lee et al. Psychiatry Investigation
- Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease
- (2016) Simon J. Beck et al. Nature Communications
- Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
- (2016) Alice Polchi et al. Nanomaterials
- Stem Cell Therapy and Immunological Rejection in Animal Models
- (2016) Xiaowei Jin et al. Current Molecular Pharmacology
- Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model
- (2015) Se Hee Oh et al. CELL TRANSPLANTATION
- Transplantation of placenta-derived mesenchymal stem cells reduces hypoxic-ischemic brain damage in rats by ameliorating the inflammatory response
- (2015) Hongfang Ding et al. Cellular & Molecular Immunology
- Human Umbilical Cord-Derived Mesenchymal Stem Cells Improve Learning and Memory Function in Hypoxic-Ischemic Brain-Damaged Rats via an IL-8-Mediated Secretion Mechanism Rather than Differentiation Pattern Induction
- (2015) Xiaoqin Zhou et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- A developmental framework for induced pluripotency
- (2015) Kazutoshi Takahashi et al. DEVELOPMENT
- Galantamine-loaded solid–lipid nanoparticles for enhanced brain delivery: preparation, characterization,in vitroandin vivoevaluations
- (2015) Shubham Misra et al. DRUG DELIVERY
- Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss
- (2015) Rahasson R. Ager et al. HIPPOCAMPUS
- Alpha amylase assisted synthesis of TiO2 nanoparticles: Structural characterization and application as antibacterial agents
- (2015) Razi Ahmad et al. JOURNAL OF HAZARDOUS MATERIALS
- Neural stem cell transplantation decreases neuroinflammation in a transgenic mouse model of Alzheimer's disease
- (2015) Qi Zhang et al. JOURNAL OF NEUROCHEMISTRY
- Human umbilical cord blood-derived mesenchymal stem cells improve functional recovery through thrombospondin1, pantraxin3, and vascular endothelial growth factor in the ischemic rat brain
- (2015) Hyung Woo Park et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity
- (2015) Yosra S.R. Elnaggar et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Disruption of Amyloid Prion Protein Aggregates by Cationic Pyridylphenylene Dendrimers
- (2015) Svetlana A. Sorokina et al. MACROMOLECULAR BIOSCIENCE
- The Role of TDP-43 in Alzheimer’s Disease
- (2015) Xiao-Long Chang et al. MOLECULAR NEUROBIOLOGY
- The Role of Cdk5 in Alzheimer’s Disease
- (2015) Shu-Lei Liu et al. MOLECULAR NEUROBIOLOGY
- Nanomedicine for the treatment of Alzheimer's disease
- (2015) Maria Gregori et al. Nanomedicine
- A review on Alzheimer's disease pathophysiology and its management: an update
- (2015) Anil Kumar et al. Pharmacological Reports
- Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5
- (2015) G. Stefano Brigidi et al. Nature Communications
- Antibacterial Effect of Green Synthesized TiO2 Nanoparticles
- (2014) Razi Ahmad et al.
- Nanoliposomes presenting on surface a cis-glycofused benzopyran compound display binding affinity and aggregation inhibition ability towards Amyloid β1-42 peptide
- (2014) Cristina Airoldi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Pharmacotherapy of Alzheimer’s disease: current and future trends
- (2014) Werner J Geldenhuys et al. Expert Review of Neurotherapeutics
- Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders
- (2014) Keun-A Chang et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Stem-Cell Challenges in the Treatment of Alzheimer's Disease: A Long Way from Bench to Bedside
- (2014) Xiaotang Fan et al. MEDICINAL RESEARCH REVIEWS
- Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease
- (2014) Michael B. Dinkins et al. NEUROBIOLOGY OF AGING
- TDP-43 interaction with the intracellular domain of amyloid precursor protein induces p53-associated apoptosis
- (2014) Jing Wang et al. NEUROSCIENCE LETTERS
- Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients
- (2014) Yu-Sheng Fang et al. Nature Communications
- Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies
- (2013) Alaa H. Abuznait et al. ACS Chemical Neuroscience
- The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
- (2013) Russell H. Swerdlow et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- B6 Peptide-Modified PEG-PLA Nanoparticles for Enhanced Brain Delivery of Neuroprotective Peptide
- (2013) Zhongyang Liu et al. BIOCONJUGATE CHEMISTRY
- Cholinergic Neuron-Like Cells Derived from Bone Marrow Stromal Cells Induced by Tricyclodecane-9-yl-Xanthogenate Promote Functional Recovery and Neural Protection after Spinal Cord Injury
- (2013) Chunhui Sun et al. CELL TRANSPLANTATION
- Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease
- (2013) Zhiyou Cai et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- UCH-L1 Inhibition Involved in CREB Dephosphorylation in Hippocampal Slices
- (2013) Min Xie et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Induced neural stem cells (iNSCs) in neurodegenerative diseases
- (2013) Andreas Hermann et al. JOURNAL OF NEURAL TRANSMISSION
- Preparation and optimization of chitosan nanoparticles and magnetic chitosan nanoparticles as delivery systems using Box–Behnken statistical design
- (2013) Hamideh Elmizadeh et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
- (2013) Victor L Villemagne et al. LANCET NEUROLOGY
- The proton permeability of self-assembled polymersomes and their neuroprotection by enhancing a neuroprotective peptide across the blood–brain barrier after modification with lactoferrin
- (2013) Yuan Yu et al. Nanoscale
- Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
- (2013) Ryoko Araki et al. NATURE
- Long-term immunomodulatory effect of amniotic stem cells in an Alzheimer's disease model
- (2013) Kyung-Sul Kim et al. NEUROBIOLOGY OF AGING
- Improvement of cognitive function and physical activity of aging mice by human neural stem cells over-expressing choline acetyltransferase
- (2013) Dongsun Park et al. NEUROBIOLOGY OF AGING
- Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice
- (2013) David X. Medina et al. NEUROBIOLOGY OF AGING
- Progress in Stem Cell Therapy for Major Human Neurological Disorders
- (2013) P. L. Martínez-Morales et al. Stem Cell Reviews and Reports
- Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1–42-infused mouse model of Alzheimer’s disease
- (2013) H-M Yun et al. Cell Death & Disease
- Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer’s Disease Tg2576 Mice
- (2012) Kwok Kin Cheng et al. AAPS Journal
- Versatile and Efficient Targeting Using a Single Nanoparticulate Platform: Application to Cancer and Alzheimer’s Disease
- (2012) Benjamin Le Droumaguet et al. ACS Nano
- Experimental research Enhanced connexin 43 expression following neural stem cell transplantation in a rat model of traumatic brain injury
- (2012) Bo Yu et al. Archives of Medical Science
- Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor
- (2012) Roger Prades et al. BIOMATERIALS
- Investigation of the performance of PEG–PEI/ROCK-II-siRNA complexes for Alzheimer's disease in vitro
- (2012) Yunyun Liu et al. BRAIN RESEARCH
- Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction
- (2012) Dongsun Park et al. EXPERIMENTAL NEUROLOGY
- In vitro differentiation of human umbilical cord mesenchymal stem cells (hUCMSCs), derived from Wharton's jelly, into choline acetyltransferase (ChAT)-positive cells
- (2012) Lei Zhang et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology
- (2012) Timothy Revett et al. JOURNAL OF PSYCHIATRY & NEUROSCIENCE
- TREM2 linked to late-onset AD
- (2012) Bryony Jones Nature Reviews Neurology
- Neuroinflammation: A Common Pathway in CNS Diseases as Mediated at the Blood-Brain Barrier
- (2012) Michelle A. Erickson et al. NEUROIMMUNOMODULATION
- Curcumin Loaded-PLGA Nanoparticles Conjugated with Tet-1 Peptide for Potential Use in Alzheimer's Disease
- (2012) Anila Mathew et al. PLoS One
- Intravenous Delivery of Targeted Liposomes to Amyloid-β Pathology in APP/PSEN1 Transgenic Mice
- (2012) Eric A. Tanifum et al. PLoS One
- Concise Review: Can Stem Cells be Used to Treat or Model Alzheimer's Disease?
- (2012) Wesley W. Chen et al. STEM CELLS
- Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
- (2011) Marcus J. Calkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Encapsulation of Aβ1–15 in PLGA microparticles enhances serum antibody response in mice immunized by subcutaneous and intranasal routes
- (2011) G. Puras et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Albumin nanoparticles carrying cyclodextrins for nasal delivery of the anti-Alzheimer drug tacrine
- (2011) Barbara Luppi et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- TAR-DNA binding protein-43 and alterations in the hippocampus
- (2011) Tuomas Rauramaa et al. JOURNAL OF NEURAL TRANSMISSION
- Accumulation of Transactive Response DNA Binding Protein 43 in Mild Cognitive Impairment and Alzheimer Disease
- (2011) Cyntia Tremblay et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects
- (2011) Antonio Liras Journal of Translational Medicine
- Chitosan enhances the stability and targeting of immuno-nanovehicles to cerebro-vascular deposits of Alzheimer's disease amyloid protein
- (2011) Kristen M. Jaruszewski et al. Nanomedicine-Nanotechnology Biology and Medicine
- Immunogenicity of induced pluripotent stem cells
- (2011) Tongbiao Zhao et al. NATURE
- Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease
- (2011) Sonja Kriks et al. NATURE
- Induction of human neuronal cells by defined transcription factors
- (2011) Zhiping P. Pang et al. NATURE
- Specification of transplantable astroglial subtypes from human pluripotent stem cells
- (2011) Robert Krencik et al. NATURE BIOTECHNOLOGY
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Direct reprogramming of mouse fibroblasts to neural progenitors
- (2011) J. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Safety of Intravenous Infusion of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Animals and Humans
- (2011) Jeong Chan Ra et al. STEM CELLS AND DEVELOPMENT
- Genome-wide association reveals genetic effects on human Aβ 42 and τ protein levels in cerebrospinal fluids: a case control study
- (2010) Mi-Ryung Han et al. BMC Neurology
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease
- (2010) Adam Smith et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion
- (2010) Irfan Y. Tamboli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Teratomas from pluripotent stem cells: A clinical hurdle
- (2010) Chui-Yee Fong et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Development and evaluation of polymer nanoparticles for oral delivery of estradiol to rat brain in a model of Alzheimer's pathology
- (2010) G. Mittal et al. JOURNAL OF CONTROLLED RELEASE
- Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease
- (2010) Dimitrios Kapogiannis et al. LANCET NEUROLOGY
- Amyloid-Beta Associated with Chitosan Nano-Carrier has Favorable Immunogenicity and Permeates the BBB
- (2009) Zhang Songjiang et al. AAPS PHARMSCITECH
- Nanoparticle–chelator conjugates as inhibitors of amyloid-β aggregation and neurotoxicity: A novel therapeutic approach for Alzheimer disease
- (2009) Gang Liu et al. NEUROSCIENCE LETTERS
- Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease
- (2009) M. Blurton-Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells
- (2009) Munjal M. Acharya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
- (2008) Barnabas Wilson et al. BRAIN RESEARCH
- Taking stem cells to the clinic: Major challenges
- (2008) Ariff Bongso et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Significant delivery of tacrine into the brain using magnetic chitosan microparticles for treating Alzheimer's disease
- (2008) Barnabas Wilson et al. JOURNAL OF NEUROSCIENCE METHODS
- Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
- (2008) S. Hauptmann et al. NEUROBIOLOGY OF AGING
- BDNF improves the effects of neural stem cells on the rat model of Alzheimer's disease with unilateral lesion of fimbria-fornix
- (2008) A.G. Xuan et al. NEUROSCIENCE LETTERS
- Effects of engrafted neural stem cells in Alzheimer's disease rats
- (2008) A.G. Xuan et al. NEUROSCIENCE LETTERS
- Embryonic stem cell-derived neural precursor cells improve memory dysfunction in Aβ(1–40) injured rats
- (2008) Jun Tang et al. NEUROSCIENCE RESEARCH
- Proteomic profiling of exosomes: Current perspectives
- (2008) Richard J. Simpson et al. PROTEOMICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started