A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Treatment with a BH3 mimetic overcomes the resistance of latency III EBV (+) cells to p53-mediated apoptosis

(2011) A Pujals et al.   Cell Death & Disease

Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia

(2010) J. Long et al.   BLOOD

Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo

(2010) James G Jackson et al.   JOURNAL OF PATHOLOGY

Translating p53 into the clinic

(2010) Chit Fang Cheok et al.   Nature Reviews Clinical Oncology

p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation

(2010) M Xia et al.   ONCOGENE

Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis

(2009) Vera V. Grinkevich et al.   CANCER CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma

(2009) G Akiri et al.   ONCOGENE

Distinct Thresholds Govern Myc's Biological Output In Vivo

(2008) Daniel J. Murphy et al.   CANCER CELL

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

(2008) C. Tse et al.   CANCER RESEARCH

A complex barcode underlies the heterogeneous response of p53 to stress

(2008) Fiona Murray-Zmijewski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY