Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer’s Disease

The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma

(2019) Vivek Bhaskaran et al.   Nature Communications

Amyloid β oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate

(2019) Yang He et al.   Nature Communications

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia

(2019) Sylvia E. Perez et al.   ACTA NEUROPATHOLOGICA

Early sirtuin 2 inhibition prevents age-related cognitive decline in a senescence-accelerated mouse model

(2019) Teresa Diaz-Perdigon et al.   NEUROPSYCHOPHARMACOLOGY

MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways

(2018) Rachid El Fatimy et al.   ACTA NEUROPATHOLOGICA

Original article: Training and validation of a novel 4-miRNA ratio model (MiCaP) for prediction of post-operative outcome in prostate cancer patients

(2018) L Schmidt et al.   ANNALS OF ONCOLOGY

Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells

(2018) Qian Wu et al.   BIOCHEMICAL PHARMACOLOGY

SATB2 targeted by methylated miR-34c-5p suppresses proliferation and metastasis attenuating the epithelial-mesenchymal transition in colorectal cancer

(2018) Jingfeng Gu et al.   CELL PROLIFERATION

MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma

(2018) Adrian P. Mansini et al.   HEPATOLOGY

Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer’s disease

(2018) Boaz Styr et al.   NATURE NEUROSCIENCE

Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells

(2018) Xiaoman Chen et al.   MOLECULAR PHARMACEUTICS

microRNA diagnostic panel for Alzheimer’s disease and epigenetic trade-off between neurodegeneration and cancer

(2018) Siranjeevi Nagaraj et al.   AGEING RESEARCH REVIEWS

Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development

(2018) Tomasz J. Nowakowski et al.   NATURE NEUROSCIENCE

Elevation of Peripheral BDNF Promoter Methylation Predicts Conversion from Amnestic Mild Cognitive Impairment to Alzheimer’s Disease: A 5-Year Longitudinal Study

(2017) Bing Xie et al.   JOURNAL OF ALZHEIMERS DISEASE

DNA Methylation and Tag SNPs of the BDNF Gene in Conversion of Amnestic Mild Cognitive Impairment into Alzheimer’s Disease: A Cross-Sectional Cohort Study

(2017) Bing Xie et al.   JOURNAL OF ALZHEIMERS DISEASE

Low Expression of Circulating MicroRNA-34c is Associated with Poor Prognosis in Triple-Negative Breast Cancer

(2017) Zhihao Zeng et al.   YONSEI MEDICAL JOURNAL

Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1

(2017) Stuart K. Calderwood et al.   Frontiers in Neuroscience

MicroRNA epigenetic signatures in human disease

(2016) Klara Piletič et al.   ARCHIVES OF TOXICOLOGY

Evaluation of MiR-34 Family and DNA Methyltransferases 1, 3A, 3B Gene Expression Levels in Hepatocellular Carcinoma Following Treatment with Dendrosomal Nanocurcumin

(2016) Fatemeh Chamani et al.   Asian Pacific Journal of Cancer Prevention

Inverse relationship between Alzheimer’s disease and cancer, and other factors contributing to Alzheimer’s disease: a systematic review

(2016) Ovais Shafi   BMC Neurology

Nec‐1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice

(2016) Seung‐Hoon Yang et al.   EMBO Molecular Medicine

Increased Serum miR-206 Level Predicts Conversion from Amnestic Mild Cognitive Impairment to Alzheimer’s Disease: A 5-Year Follow-up Study

(2016) Bing Xie et al.   JOURNAL OF ALZHEIMERS DISEASE

Deregulation of miRNA-181c potentially contributes to the pathogenesis of AD by targeting collapsin response mediator protein 2 in mice

(2016) Huimin Zhou et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

MiR-137: an important player in neural development and neoplastic transformation

(2016) E Mahmoudi et al.   MOLECULAR PSYCHIATRY

The orphan nuclear receptor NR4A2 is part of a p53–microRNA-34 network

(2016) Jordan A. Beard et al.   Scientific Reports

The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer’s disease

(2016) Annika Öhrfelt et al.   Alzheimers Research & Therapy

MicroRNA-34c Suppresses Breast Cancer Migration and Invasion by Targeting GIT1

(2016) Wei-Yang Tao et al.   Journal of Cancer

Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo

(2015) Shu Yang et al.   BMC CANCER

The Regulation and Function of miR-21-FOXO3a-miR-34b/c Signaling in Breast Cancer

(2015) Xiangyan Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission

(2015) C. S. Evans et al.   JOURNAL OF NEUROSCIENCE

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

(2014) Christopher J. Cheng et al.   NATURE

Increased microRNA-34c abundance in Alzheimer's disease circulating blood plasma

(2014) Shephali Bhatnagar et al.   Frontiers in Molecular Neuroscience

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

(2013) Hans Zempel et al.   EMBO JOURNAL

Screening of microRNAs associated with Alzheimer's disease using oxidative stress cell model and different strains of senescence accelerated mice

(2013) Rui Zhang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid

(2013) Mareike Müller et al.   NEUROBIOLOGY OF AGING

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE