标题
Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 40, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-01-11
DOI
10.1186/s13046-020-01824-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Development and validation of a prognostic classifier based on HIF-1 signaling for hepatocellular carcinoma
- (2020) Feiwen Deng et al. Aging-US
- Endoplasmic Reticulum Stress Signaling in Cancer Cells
- (2020) Scott A. Oakes AMERICAN JOURNAL OF PATHOLOGY
- The interplay between HIF-1α and noncoding RNAs in cancer
- (2020) Xiafeng Peng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias
- (2020) Alberto M. Martelli et al. Cancers
- Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
- (2020) Sylwia Bartoszewska et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Mechanisms, regulation and functions of the unfolded protein response
- (2020) Claudio Hetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers
- (2020) Kunming Zhao et al. PLOS BIOLOGY
- Metabolic Heterogeneity of Cancer Cells: An Interplay between HIF-1, GLUTs, and AMPK
- (2020) Nurbubu T. Moldogazieva et al. Cancers
- Molecular Chaperones in Cancer Stem Cells: Determinants of Stemness and Potential Targets for Antitumor Therapy
- (2020) Alexander Kabakov et al. Cells
- The IRE1 pathway regulates honey bee Unfolded Protein Response gene expression
- (2020) Tara Reyes Adames et al. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma
- (2020) Junhui Liu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs)
- (2020) Rosamaria Lappano et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer
- (2020) Antonietta Rosella Farina et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Targeting of endoplasmic reticulum (ER) stress in gliomas
- (2020) Mariam Markouli et al. PHARMACOLOGICAL RESEARCH
- Energy metabolism in cancer stem cells
- (2020) Xuan Zhu et al. World Journal of Stem Cells
- The role of microenvironment in tumor angiogenesis
- (2020) Xianjie Jiang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Targeting tumor hypoxia and mitochondrial metabolism with anti-parasitic drugs to improve radiation response in high-grade gliomas
- (2020) Faiqa Mudassar et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxia-autophagy axis induces VEGFA by peritoneal mesothelial cells to promote gastric cancer peritoneal metastasis through an integrin α5-fibronectin pathway
- (2020) Xiaoxun Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production
- (2020) Weijian Zhang et al. TOXICOLOGY LETTERS
- Pharmacologic Targeting of Hypoxia-Inducible Factors
- (2019) Gregg L. Semenza Annual Review of Pharmacology and Toxicology
- Hypoxia Activated Prodrugs of PERK Inhibitors
- (2019) Lydia P. Liew et al. Chemistry-An Asian Journal
- Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells
- (2019) Mohana Krishna Gopisetty et al. JOURNAL OF NANOBIOTECHNOLOGY
- The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection
- (2019) Hai Hu et al. Frontiers in Immunology
- HIF Inhibitors: Status of Current Clinical Development
- (2019) Jaleh Fallah et al. Current Oncology Reports
- Plasma microRNAs Predict Chemoresistance in Patients With Metastatic Breast Cancer
- (2019) Bin Shao et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- Hypoxia Induced ER Stress Response as an Adaptive Mechanism in Cancer
- (2019) Sandhya Chipurupalli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma
- (2019) Junling Zhuang et al. BLOOD
- Wnt/IL‐1β/IL‐8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5
- (2019) Vladan Milosevic et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer
- (2019) Luigi Ippolito et al. ONCOGENE
- Mutant p53 and Cellular Stress Pathways: A Criminal Alliance That Promotes Cancer Progression
- (2019) Gabriella D’Orazi et al. Cancers
- HIF-1α is overexpressed in leukemic cells from TP53-disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia
- (2019) Valentina Griggio et al. HAEMATOLOGICA
- Hypoxic ER stress suppresses β-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1α for cell survival
- (2019) Zhixiong Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pharmacological targeting of the unfolded protein response for disease intervention
- (2019) Claudio Hetz et al. Nature Chemical Biology
- Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts
- (2019) Elena Gazzano et al. CANCER LETTERS
- Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma
- (2019) Jinkyu Jung et al. CANCER RESEARCH
- What sustains the multidrug resistance phenotype beyond ABC efflux transporters? Looking beyond the tip of the iceberg
- (2019) Teodora Alexa-Stratulat et al. DRUG RESISTANCE UPDATES
- NAMPT Inhibition Suppresses Cancer Stem-like Cells Associated with Therapy-Induced Senescence in Ovarian Cancer
- (2019) Timothy Nacarelli et al. CANCER RESEARCH
- Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
- (2019) David Kung-Chun Chiu et al. Cell Death & Disease
- Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications
- (2019) Wei Sun et al. Cells
- miRNAs regulate the HIF switch during hypoxia: a novel therapeutic target
- (2018) Marcin Serocki et al. ANGIOGENESIS
- Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
- (2018) Debangshu Samanta et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication
- (2018) Andrew Melber et al. CELL RESEARCH
- Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors
- (2018) Milan Hano et al. MOLECULES
- PERK/eIF2α signaling inhibits HIF-induced gene expression during the unfolded protein response via YB1-dependent regulation of HIF1α translation
- (2018) Iglika G Ivanova et al. NUCLEIC ACIDS RESEARCH
- Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis
- (2018) Huichun Liang et al. ONCOGENE
- The role of HIF-1α in chemo-/radioresistant tumors
- (2018) Yu Xia et al. OncoTargets and Therapy
- Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78
- (2018) Youli Cai et al. Cell Death & Disease
- Targeting multidrug-resistant ovarian cancer through estrogen receptor α dependent ATP depletion caused by hyperactivation of the unfolded protein response
- (2018) Xiaobin Zheng et al. Oncotarget
- Prognostic Role of Hypoxia-Inducible Factor-2α Tumor Cell Expression in Cancer Patients: A Meta-Analysis
- (2018) Eloy Moreno Roig et al. Frontiers in Oncology
- LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
- (2018) Inna Serganova et al. PLoS One
- BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
- (2018) Andrew G. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of the unfolded protein response in cancer progression: From oncogenesis to chemoresistance
- (2018) Emma Madden et al. BIOLOGY OF THE CELL
- Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma
- (2018) Ilaria Buondonno et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation
- (2018) Jian Wu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin
- (2018) Miao He et al. Molecular Oncology
- New horizons in hypoxia signaling pathways
- (2017) Christopher W. Pugh et al. EXPERIMENTAL CELL RESEARCH
- PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
- (2017) Iris C. Salaroglio et al. Molecular Cancer
- The mitochondrial UPR: mechanisms, physiological functions and implications in ageing
- (2017) Tomer Shpilka et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism
- (2017) Weinan Du et al. Nature Communications
- VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
- (2017) Xiaosai Yao et al. Cancer Discovery
- The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction
- (2017) Giulia Cheloni et al. Stem Cells International
- Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs)
- (2017) Li Wang et al. PLoS One
- HIF-1-mediated suppression of mitochondria electron transport chain function confers resistance to lidocaine-induced cell death
- (2017) Akihisa Okamoto et al. Scientific Reports
- Hypoxia-inducible factor 3 biology: complexities and emerging themes
- (2016) Cunming Duan AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Isoproterenol regulates CD44 expression in gastric cancer cells through STAT3/MicroRNA373 cascade
- (2016) Bo Wei et al. BIOMATERIALS
- Phenotypic and genomic analysis of multiple myeloma minimal residual disease tumor cells: a new model to understand chemoresistance
- (2016) B. Paiva et al. BLOOD
- Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells
- (2016) Baoqing Guo et al. BMC CANCER
- Hypoxia regulates ABCG2activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells
- (2016) Xiaodan He et al. CANCER BIOLOGY & THERAPY
- Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
- (2016) Kimberly J. Briggs et al. CELL
- PERK Integrates Oncogenic Signaling and Cell Survival During Cancer Development
- (2016) Yiwen Bu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer
- (2016) Jian Yang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Membrane Protein Quantity Control at the Endoplasmic Reticulum
- (2016) Ignat Printsev et al. JOURNAL OF MEMBRANE BIOLOGY
- Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma
- (2016) Alexander W. Eckert et al. Journal of Translational Medicine
- Naringenin ameliorates hypoxia/reoxygenation-induced endoplasmic reticulum stress-mediated apoptosis in H9c2 myocardial cells: involvement in ATF6, IRE1α and PERK signaling activation
- (2016) Jia-You Tang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species
- (2016) Noel A. Warfel et al. MOLECULAR CANCER THERAPEUTICS
- Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors
- (2016) Joanna Kopecka et al. Oncotarget
- Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cells
- (2016) Josep Maria Cornet-Masana et al. Oncotarget
- Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis
- (2016) Asaha Fujimoto et al. Oncotarget
- Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1
- (2015) Helena Doktorova et al. BIOMEDICAL PAPERS-OLOMOUC
- Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α–ZEB1 axis
- (2015) Justin V. Joseph et al. CANCER LETTERS
- SnapShot: Hypoxia-Inducible Factors
- (2015) Kyoung Eun Lee et al. CELL
- Exploiting a novel miR-519c–HuR–ABCG2 regulatory pathway to overcome chemoresistance in colorectal cancer
- (2015) Kenneth K.W. To et al. EXPERIMENTAL CELL RESEARCH
- HIF-1 at the crossroads of hypoxia, inflammation, and cancer
- (2015) Kuppusamy Balamurugan INTERNATIONAL JOURNAL OF CANCER
- The Role of C/EBP-β LIP in Multidrug Resistance
- (2015) Chiara Riganti et al. JNCI-Journal of the National Cancer Institute
- An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response
- (2015) Aude De Gassart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
- (2015) L R Palam et al. Cell Death & Disease
- Bortezomib attenuates HIF-1- but not HIF-2-mediated transcriptional activation
- (2015) NORAINI ABD-AZIZ et al. Oncology Letters
- Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis
- (2015) E. Chevet et al. Cancer Discovery
- Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells
- (2015) Joanna Kopecka et al. Oncotarget
- Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells
- (2015) Micol Rigoni et al. Oncotarget
- Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy
- (2015) Ruud Weijer et al. Oncotarget
- Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells
- (2015) Joanna Kopecka et al. Oncotarget
- Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma
- (2015) Mohamed A.Y. Abdel Malek et al. Oncotarget
- ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy
- (2015) Mattheus C.B. Wielenga et al. Cell Reports
- The Role of C/EBP-β LIP in Multidrug Resistance
- (2015) Chiara Riganti et al. JNCI-Journal of the National Cancer Institute
- Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms
- (2015) Jahangir Abdi et al. Oncotarget
- Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma
- (2015) Iris Chiara Salaroglio et al. Oncotarget
- Apelin is transcriptionally regulated by ER stress-induced ATF4 expression via a p38 MAPK-dependent pathway
- (2014) Kwon Jeong et al. APOPTOSIS
- Metabolic orchestration between cancer cells and tumor microenvironment as a co-evolutionary source of chemoresistance in ovarian cancer: A therapeutic implication
- (2014) Dong Hoon Suh et al. BIOCHEMICAL PHARMACOLOGY
- Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response
- (2014) S R McKeown BRITISH JOURNAL OF RADIOLOGY
- The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy
- (2014) Elisabetta Rovida et al. CELL CYCLE
- The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma
- (2014) G Tufo et al. CELL DEATH AND DIFFERENTIATION
- The anti-androgen drug dutasteride renders triple negative breast cancer cells more sensitive to chemotherapy via inhibition of HIF-1α-/VEGF-signaling
- (2014) Marie-Kristin von Wahlde et al. GYNECOLOGICAL ENDOCRINOLOGY
- Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
- (2014) Xiao-Hong Ma et al. JOURNAL OF CLINICAL INVESTIGATION
- VEGF Signals through ATF6 and PERK to Promote Endothelial Cell Survival and Angiogenesis in the Absence of ER Stress
- (2014) Evdoxia Karali et al. MOLECULAR CELL
- XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
- (2014) Xi Chen et al. NATURE
- Tanshinone IIA blocks epithelial-mesenchymal transition through HIF-1α downregulation, reversing hypoxia-induced chemotherapy resistance in breast cancer cell lines
- (2014) PEIFEN FU et al. ONCOLOGY REPORTS
- Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET
- (2014) Erinn B. Rankin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest
- (2014) S Raz et al. Cell Death & Disease
- Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival
- (2014) Mireille Khacho et al. Nature Communications
- Hypoxia-regulated microRNAs in human cancer
- (2013) Guomin Shen et al. ACTA PHARMACOLOGICA SINICA
- Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy
- (2013) Jian Zhang et al. ANTI-CANCER DRUGS
- Characterization of a Novel PERK Kinase Inhibitor with Antitumor and Antiangiogenic Activity
- (2013) C. Atkins et al. CANCER RESEARCH
- Hypoxic Activation of the PERK/eIF2 Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3
- (2013) H. Mujcic et al. CLINICAL CANCER RESEARCH
- Role of hypoxia-inducible factors in breast cancer metastasis
- (2013) Daniele M Gilkes et al. Future Oncology
- Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)
- (2013) Ethel R. Pereira et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two phases of disulfide bond formation have differing requirements for oxygen
- (2013) Marianne Koritzinsky et al. JOURNAL OF CELL BIOLOGY
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses
- (2013) Joanna Obacz et al. Molecular Cancer
- Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/ -catenin pathway
- (2013) C. Riganti et al. NEURO-ONCOLOGY
- The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
- (2013) Wafa B’chir et al. NUCLEIC ACIDS RESEARCH
- PERK/eIF2 signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
- (2013) K. M. Rouschop et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia
- (2013) Dan Cojocari et al. RADIOTHERAPY AND ONCOLOGY
- Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia
- (2013) LIHONG PI et al. Oncology Letters
- MicroRNA-10b is a Prognostic Indicator in Colorectal Cancer and Confers Resistance to the Chemotherapeutic Agent 5-Fluorouracil in Colorectal Cancer Cells
- (2012) Naohiro Nishida et al. ANNALS OF SURGICAL ONCOLOGY
- HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast
- (2012) Sophie Doublier et al. BMC CANCER
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- The PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells
- (2012) Monika Kusio-Kobialka et al. CELL CYCLE
- HIF1 is a central regulator of collagen hydroxylation and secretion under hypoxia during bone development
- (2012) L. Bentovim et al. DEVELOPMENT
- IRE1 Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2
- (2012) J.-P. Upton et al. SCIENCE
- The VHL/HIF axis in clear cell renal carcinoma
- (2012) Chuan Shen et al. SEMINARS IN CANCER BIOLOGY
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- The oncogenic PIM kinase family regulates drug resistance through multiple mechanisms
- (2011) Methvin Isaac et al. DRUG RESISTANCE UPDATES
- Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
- (2011) Nadine Rohwer et al. DRUG RESISTANCE UPDATES
- A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia
- (2011) F. Bouquet et al. JOURNAL OF CELL SCIENCE
- The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
- (2011) Brian F. Teske et al. MOLECULAR BIOLOGY OF THE CELL
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Invited review: decoding the microRNA response to hypoxia
- (2011) Roger Pocock PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Hypoxia prevents etoposide-induced DNA damage in cancer cells through a mechanism involving hypoxia-inducible factor 1
- (2009) R. Sullivan et al. MOLECULAR CANCER THERAPEUTICS
- Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
- (2009) T. Iwawaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of lentivirus-mediated HIF-1α knockdown on hypoxia-related cisplatin resistance and their dependence on p53 status in fibrosarcoma cells
- (2008) J Hao et al. CANCER GENE THERAPY
- Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
- (2008) J. Chiche et al. CANCER RESEARCH
- Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 -deficient mouse embryonic fibroblasts
- (2008) R. Wirthner et al. CARCINOGENESIS
- Hypoxia-mediated up-regulation of MGr1-Ag/37LRP in gastric cancers occurs via hypoxia-inducible-factor 1-dependent mechanism and contributes to drug resistance
- (2008) Lili Liu et al. INTERNATIONAL JOURNAL OF CANCER
- Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity
- (2008) R. Sullivan et al. MOLECULAR CANCER THERAPEUTICS
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started