标题
miRNAs regulate the HIF switch during hypoxia: a novel therapeutic target
作者
关键词
microRNAs, HIFs, Hypoxia, Target protectors, Morpholinos
出版物
ANGIOGENESIS
Volume 21, Issue 2, Pages 183-202
出版商
Springer Nature
发表日期
2018-01-27
DOI
10.1007/s10456-018-9600-2
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells
- (2017) Rafal Bartoszewski et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
- (2017) Mircea Ivan et al. MOLECULAR CELL
- Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial–mesenchymal transition by regulating HIF-1α via miR-138
- (2017) Qiang Cai et al. Open Biology
- SNPs in microRNA target sites and their potential role in human disease
- (2017) Adrianna Moszyńska et al. Open Biology
- Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro
- (2016) Tessa D. Nauta et al. ANGIOGENESIS
- A novel hypoxia-induced miR-147a regulates cell proliferation through a positive feedback loop of stabilizing HIF-1α
- (2016) Fan Wang et al. CANCER BIOLOGY & THERAPY
- A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
- (2016) Eli M. Wallace et al. CANCER RESEARCH
- Posttranscriptional and transcriptional regulation of endothelial nitric-oxide synthase during hypoxia: the role of microRNAs
- (2016) Leszek Kalinowski et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2αCLINICAL PERSPECTIVE
- (2016) Zhiyu Dai et al. CIRCULATION
- Down-regulation of TIMP2 by HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
- (2016) Alan Ka-Lun Kai et al. HEPATOLOGY
- Exosomal transfer of miR-30a between cardiomyocytes regulates autophagy after hypoxia
- (2016) Yan Yang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- MicroRNA-433 Inhibits the Proliferation and Migration of HUVECs and Neurons by Targeting Hypoxia-Inducible Factor 1 Alpha
- (2016) Lin Zhang et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- MicroRNA-103/107 is involved in hypoxia-induced proliferation of pulmonary arterial smooth muscle cells by targeting HIF-1β
- (2016) Bi Deng et al. LIFE SCIENCES
- MicroRNA-363 and GATA-1 are regulated by HIF-1α in K562 cells under hypoxia
- (2016) Youbang Xie et al. Molecular Medicine Reports
- Overexpression of microRNA-210 promotes chondrocyte proliferation and extracellular matrix deposition by targeting HIF-3α in osteoarthritis
- (2016) ZHIFU LI et al. Molecular Medicine Reports
- Long noncoding RNAs in kidney and cardiovascular diseases
- (2016) Johan M. Lorenzen et al. Nature Reviews Nephrology
- Single nucleotide polymorphism in the microRNA-199a binding site of HIF1A gene is associated with pancreatic ductal adenocarcinoma risk and worse clinical outcomes
- (2016) Xiuchao Wang et al. Oncotarget
- microRNA-558 facilitates the expression of hypoxia-inducible factor 2 alpha through binding to 5′-untranslated region in neuroblastoma
- (2016) Hongxia Qu et al. Oncotarget
- MicroRNA-421 regulated by HIF-1α promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric cancer
- (2016) Xiaoxiao Ge et al. Oncotarget
- MicroRNA-206 attenuates the growth and angiogenesis in non-small cell lung cancer cells by blocking the 14-3-3ζ/STAT3/HIF-1α/VEGF signaling
- (2016) Dong Xue et al. Oncotarget
- Role of Mir-155 in Controlling HIF-1α Level and Promoting Endothelial Cell Maturation
- (2016) Deguang Yang et al. Scientific Reports
- MiR675-5p Acts on HIF-1α to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma
- (2016) Alessia Lo Dico et al. Theranostics
- Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
- (2016) Javier Rodriguez et al. Cell Reports
- miR‐17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia‐Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation
- (2016) Tianji Chen et al. Journal of the American Heart Association
- Correction: HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells
- (2016) Tessa D. Nauta et al. PLoS One
- miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells
- (2016) Anna Janaszak-Jasiecka et al. Scientific Reports
- Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis
- (2015) C Blick et al. BRITISH JOURNAL OF CANCER
- Hypoxia promotes apoptosis of neuronal cells through hypoxia-inducible factor-1α-microRNA-204-B-cell lymphoma-2 pathway
- (2015) Xiuwen Wang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop
- (2015) Sylwia Bartoszewska et al. FASEB JOURNAL
- HIF3α: the little we know
- (2015) Linda Ravenna et al. FEBS Journal
- Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene
- (2015) Satomi Kobayashi et al. GENES TO CELLS
- Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy
- (2015) I. Spinello et al. HAEMATOLOGICA
- Endothelial Hypoxia-Inducible Factor-1α Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a
- (2015) Shamima Akhtar et al. HYPERTENSION
- Impaired expression of HIF-2α induces compensatory expression of HIF-1α for the recovery from anemia
- (2015) Ikki Tsuboi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury
- (2015) K. Bhatt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond
- (2015) Patrick H. Maxwell et al. Nature Reviews Nephrology
- The role of hypoxia-inducible factor-2 in digestive system cancers
- (2015) J Zhao et al. Cell Death & Disease
- microRNA-18a regulates gastric carcinoma cell apoptosis and invasion by suppressing hypoxia-inducible factor-1α expression
- (2015) FUBING WU et al. Experimental and Therapeutic Medicine
- HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironment.
- (2015) Neha Nagpal et al. Scientific Reports
- Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy
- (2015) I. Spinello et al. HAEMATOLOGICA
- MicroRNA-18a Decreases Choroidal Endothelial Cell Proliferation and Migration by Inhibiting HIF1A Expression
- (2015) Wei Jiang MEDICAL SCIENCE MONITOR
- Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1
- (2014) T. Umezu et al. BLOOD
- A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes
- (2014) Yang Liu et al. FEBS LETTERS
- Sox9 and Hif-2α regulate TUBB3 gene expression and affect ovarian cancer aggressiveness
- (2014) Giuseppina Raspaglio et al. GENE
- Modulation of hypoxia-signaling pathways by extracellular linc-RoR
- (2014) K. Takahashi et al. JOURNAL OF CELL SCIENCE
- Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia
- (2014) Carme Camps et al. Molecular Cancer
- MicroRNA-382 induced by HIF-1α is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog
- (2014) Jin-Kyung Seok et al. NUCLEIC ACIDS RESEARCH
- Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression
- (2014) Rajesha Rupaimoole et al. Nature Communications
- Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER
- (2014) Twan van den Beucken et al. Nature Communications
- Hypoxia-Inducible Factor 3 Is an Oxygen-Dependent Transcription Activator and Regulates a Distinct Transcriptional Response to Hypoxia
- (2014) Peng Zhang et al. Cell Reports
- HypoxamiR Regulation and Function in Ischemic Cardiovascular Diseases
- (2013) Simona Greco et al. ANTIOXIDANTS & REDOX SIGNALING
- Transcriptional regulation by hypoxia inducible factors
- (2013) Veronica L. Dengler et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect
- (2013) Fan Yang et al. MOLECULAR CELL
- Regulation of the Hif-system by micro-RNA 17 and 20a – Role during monocyte-to-macrophage differentiation
- (2013) David M. Poitz et al. MOLECULAR IMMUNOLOGY
- RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts
- (2013) Sarah Geisler et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HIF-1 is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2 -induced excessive erythropoiesis
- (2012) K. Franke et al. BLOOD
- HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation
- (2012) M He et al. CELL DEATH AND DIFFERENTIATION
- Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
- (2012) Yan Xia et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Functional Importance of Dicer Protein in the Adaptive Cellular Response to Hypoxia
- (2012) J. J. David Ho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-Induced MicroRNA-20a Expression Increases ERK Phosphorylation and Angiogenic Gene Expression in Endometriotic Stromal Cells
- (2012) Shih-Chieh Lin et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha
- (2012) H Zhang et al. ONCOGENE
- MicroRNA 107 Partly Inhibits Endothelial Progenitor Cells Differentiation via HIF-1β
- (2012) Shu Meng et al. PLoS One
- Hypoxia-Induced Alternative Splicing in Endothelial Cells
- (2012) Julia E. Weigand et al. PLoS One
- Acute versus chronic hypoxia in tumors
- (2012) C. Bayer et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Passing the baton: the HIF switch
- (2012) Mei Yee Koh et al. TRENDS IN BIOCHEMICAL SCIENCES
- HIF-1 versus HIF-2 — Is one more important than the other?
- (2012) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- The Hypoxia-Associated Factor Switches Cells from HIF-1 - to HIF-2 -Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
- (2011) M. Y. Koh et al. CANCER RESEARCH
- Characterization of novel antisense HIF-1α transcripts in human cancers
- (2011) Davide Bertozzi et al. CELL CYCLE
- Upregulation of MicroRNA-210 Regulates Renal Angiogenesis Mediated by Activation of VEGF Signaling Pathway under Ischemia/Perfusion Injury in vivo and in vitro
- (2011) Fen Liu et al. KIDNEY & BLOOD PRESSURE RESEARCH
- MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1 Activity during Prolonged Hypoxia
- (2011) U. Bruning et al. MOLECULAR AND CELLULAR BIOLOGY
- Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo
- (2011) Alison A Staton et al. Nature Protocols
- Dynamic mechanisms for pre-miRNA binding and export by Exportin-5
- (2011) X. Wang et al. RNA
- MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT
- (2010) Zhan Zhang et al. CELL CYCLE
- MicroRNA-210: A unique and pleiotropic hypoxamir
- (2010) Stephen Y. Chan et al. CELL CYCLE
- The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism
- (2010) Na Zhang et al. Cell Metabolism
- Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2
- (2010) Annika Pasanen et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- miR-200b Targets Ets-1 and Is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells
- (2010) Yuk Cheung Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
- (2010) Goutam Ghosh et al. JOURNAL OF CLINICAL INVESTIGATION
- Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing
- (2010) Chanseok Shin et al. MOLECULAR CELL
- Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α
- (2010) Ji-Hong Lim et al. MOLECULAR CELL
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age
- (2010) Nicole Noren Hooten et al. PLoS One
- P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
- (2010) M. Yamakuchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA sponges: Progress and possibilities
- (2010) M. S. Ebert et al. RNA
- A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity
- (2010) D. Cifuentes et al. SCIENCE
- MicroRNAs Induced During Ischemic Preconditioning
- (2010) Soon-Tae Lee et al. STROKE
- Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis
- (2009) N. Skuli et al. BLOOD
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Kruppel-like Factor 2 Inhibits Hypoxia-inducible Factor 1α Expression and Function in the Endothelium
- (2009) Daiji Kawanami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
- (2009) David R. Mole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
- (2009) Weibo Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation
- (2009) Xin Huang et al. MOLECULAR CELL
- Many roads to maturity: microRNA biogenesis pathways and their regulation
- (2009) Julia Winter et al. NATURE CELL BIOLOGY
- Generating specificity and diversity in the transcriptional response to hypoxia
- (2009) Urban Lendahl et al. NATURE REVIEWS GENETICS
- Regulation of HIF-1α and VEGF by miR-20b Tunes Tumor Cells to Adapt to the Alteration of Oxygen Concentration
- (2009) Zhang Lei et al. PLoS One
- HIF-1 attenuates Ref-1 expression in endothelial cells: Reversal by siRNA and inhibition of geranylgeranylation
- (2009) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- Biology of HIF-1α
- (2008) A Weidemann et al. CELL DEATH AND DIFFERENTIATION
- Biology of hypoxia-inducible factor-2α in development and disease
- (2008) S A Patel et al. CELL DEATH AND DIFFERENTIATION
- hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer
- (2008) C. Camps et al. CLINICAL CANCER RESEARCH
- MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3
- (2008) Pasquale Fasanaro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
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