Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells

Stress management by autophagy: Implications for chemoresistance

(2016) Zhao Huang et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy and p53

(2016) Eileen White   Cold Spring Harbor Perspectives in Medicine

Cell Death Signaling

(2015) Douglas R. Green et al.   Cold Spring Harbor Perspectives in Biology

Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: Utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment

(2015) Sílvia Cufí et al.   Oncotarget

Non-canonical autophagy: An exception or an underestimated form of autophagy?

(2014) Francesca Scarlatti et al.   Autophagy

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

(2014) Marie Stampe Ostenfeld et al.   Autophagy

Combined MTOR and autophagy inhibition

(2014) Reshma Rangwala et al.   Autophagy

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Chloroquine Eliminates Cancer Stem Cells Through Deregulation of Jak2 and DNMT1

(2014) Dong Soon Choi et al.   STEM CELLS

Blockade of Autophagy Aggravates Endoplasmic Reticulum Stress and Improves Paclitaxel Cytotoxicity in Human Cervical Cancer Cells

(2014) Li Xu et al.   Cancer Research and Treatment

Dual inhibition of autophagy and the AKT pathway in prostate cancer

(2013) Francois Lamoureux et al.   Autophagy

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

(2013) X Sui et al.   Cell Death & Disease

Phase II study of sorafenib in patients with relapsed or refractory lymphoma

(2012) Anna Guidetti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

(2012) G M A Ajabnoor et al.   Cell Death & Disease

Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

(2011) Wei-Liang Sun et al.   Autophagy

Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA–PKcs and PARP-1

(2011) Jung-Hoon Yoon et al.   BIOCHEMICAL PHARMACOLOGY

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

Regulation of Physiologic Actions of LRRK2: Focus on Autophagy

(2011) Andrew Ferree et al.   Neurodegenerative Diseases

The Development of an Immunohistochemical Method to Detect the Autophagy-Associated Protein LC3-II in Human Tumor Xenografts

(2011) Sarah V. Holt et al.   TOXICOLOGIC PATHOLOGY

High-Mobility Group Box 1, Oxidative Stress, and Disease

(2010) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound, Z18

(2010) Songhai Tian et al.   Autophagy

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

(2010) Derek Narendra et al.   Autophagy

AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

(2010) L. Harhaji-Trajkovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism

(2010) Akiko Kuma et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts

(2009) Michal Ugarenko et al.   BIOCHEMICAL PHARMACOLOGY

Mitophagy

(2009) Aviva M. Tolkovsky   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

(2009) Zachary W. Veitch et al.   Pharmacogenetics and Genomics

Autophagy Facilitates the Development of Breast Cancer Resistance to the Anti-HER2 Monoclonal Antibody Trastuzumab

(2009) Alejandro Vazquez-Martin et al.   PLoS One

Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance

(2008) Stacey L Hembruff et al.   BMC CANCER

Autophagy and autophagic cell death are next targets for elimination of the resistance to tyrosine kinase inhibitors

(2008) Yuko Mishima et al.   CANCER SCIENCE

Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

(2008) F Scarlatti et al.   CELL DEATH AND DIFFERENTIATION

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE