Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
出版年份 2019 全文链接
标题
Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
作者
关键词
-
出版物
Cell Death & Disease
Volume 10, Issue 12, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-12-09
DOI
10.1038/s41419-019-2155-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Induction of Oxidative Stress via Inhibition of Thioredoxin Reductase 1 is an Effective Therapeutic Approach for Hepatocellular Carcinoma
- (2018) Derek Lee et al. HEPATOLOGY
- Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma
- (2017) Derek Lee et al. JOURNAL OF CLINICAL INVESTIGATION
- Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
- (2017) Anthony B El-Khoueiry et al. LANCET
- PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma
- (2016) S. Agnihotri et al. CANCER RESEARCH
- NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma
- (2016) R. K.-H. Lai et al. CLINICAL CANCER RESEARCH
- PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy
- (2016) Kenneth R. Pryde et al. JOURNAL OF CELL BIOLOGY
- Transketolase counteracts oxidative stress to drive cancer development
- (2016) Iris Ming-Jing Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling
- (2016) Eunice Yuen Ting Lau et al. Cell Reports
- Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers
- (2016) Zhixin Qiu et al. Scientific Reports
- PI3K isoform-selective inhibitors: next-generation targeted cancer therapies
- (2015) Xiang Wang et al. ACTA PHARMACOLOGICA SINICA
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Novel Basic Helix–Loop–Helix Transcription Factor Hes4 Antagonizes the Function of Twist-1 to Regulate Lineage Commitment of Bone Marrow Stromal/Stem Cells
- (2015) Dimitrios Cakouros et al. STEM CELLS AND DEVELOPMENT
- PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402
- (2014) Liesbeth Aerts et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease
- (2014) Roberta Tufi et al. NATURE CELL BIOLOGY
- PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
- (2014) V. A. Morais et al. SCIENCE
- PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1
- (2014) Raquel Requejo-Aguilar et al. Nature Communications
- PINK1-mediated Phosphorylation of Miro Inhibits Synaptic Growth and Protects Dopaminergic Neurons in Drosophila
- (2014) Pei-I Tsai et al. Scientific Reports
- PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage
- (2013) G Arena et al. CELL DEATH AND DIFFERENTIATION
- The genetic landscape of high-risk neuroblastoma
- (2013) Trevor J Pugh et al. NATURE GENETICS
- The impact of hypoxia in hepatocellular carcinoma metastasis
- (2013) Carmen Chak-Lui Wong et al. Frontiers of Medicine
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Target Gene Analysis by Microarrays and Chromatin Immunoprecipitation Identifies HEY Proteins as Highly Redundant bHLH Repressors
- (2012) Julia Heisig et al. PLoS Genetics
- Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity
- (2011) Daniel Tello et al. Cell Metabolism
- What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
- (2011) Olga Corti et al. PHYSIOLOGICAL REVIEWS
- Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
- (2011) C. C.-L. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
- (2010) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death
- (2009) Sonia Gandhi et al. MOLECULAR CELL
- FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation
- (2009) Y. Mei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Quest for the 1p36 Tumor Suppressor
- (2008) A. Bagchi et al. CANCER RESEARCH
- PINK1heterozygous rare variants: prevalence, significance and phenotypic spectrum
- (2008) Roberta Marongiu et al. HUMAN MUTATION
- Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
- (2008) Huafeng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
- (2008) Ann-Lii Cheng et al. LANCET ONCOLOGY
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now