Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses
出版年份 2013 全文链接
标题
Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses
作者
关键词
p53, HIF-1, Hypoxia, DNA damage, Cancer
出版物
Molecular Cancer
Volume 12, Issue 1, Pages 93
出版商
Springer Nature
发表日期
2013-08-15
DOI
10.1186/1476-4598-12-93
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Autophagy takes place in mutated p53 neuroblastoma cells in response to hypoxia mimetic CoCl2
- (2013) Thomas Naves et al. BIOCHEMICAL PHARMACOLOGY
- The TP53 tumor suppressor and autophagy in malignant lymphoma
- (2012) Zijun Y. Xu-Monette et al. Autophagy
- p53 Ser15phosphorylation disrupts the p53–RPA70 complex and induces RPA70-mediated DNA repair in hypoxia
- (2012) Esha Madan et al. BIOCHEMICAL JOURNAL
- HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast
- (2012) Sophie Doublier et al. BMC CANCER
- The p53 mRNA-Mdm2 Interaction Controls Mdm2 Nuclear Trafficking and Is Required for p53 Activation following DNA Damage
- (2012) Madhavsai Gajjar et al. CANCER CELL
- CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth
- (2012) Claudia Capparelli et al. CELL CYCLE
- mTORC1 and p53
- (2012) Paul Hasty et al. CELL CYCLE
- AG490 Promotes HIF-1α Accumulation by Inhibiting Its Hydroxylation
- (2012) R. Fernandez-Sanchez et al. CURRENT MEDICINAL CHEMISTRY
- Hypoxia suppresses conversion from proliferative arrest to cellular senescence
- (2012) O. V. Leontieva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer metabolism: current perspectives and future directions
- (2012) C Muñoz-Pinedo et al. Cell Death & Disease
- Phosphorylation of Carbonic Anhydrase IX Controls Its Ability to Mediate Extracellular Acidification in Hypoxic Tumors
- (2011) P. Ditte et al. CANCER RESEARCH
- Revisiting the ABCs of Multidrug Resistance in Cancer Chemotherapy
- (2011) Amit K. Tiwari et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
- (2011) Nadine Rohwer et al. DRUG RESISTANCE UPDATES
- Carbonic Anhydrase IX Interacts with Bicarbonate Transporters in Lamellipodia and Increases Cell Migration via Its Catalytic Domain
- (2011) Eliska Svastova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chaperoning of Mutant p53 Protein by Wild-type p53 Protein Causes Hypoxic Tumor Regression
- (2011) Rajan Gogna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ubiquitin-specific Protease 19 (USP19) Regulates Hypoxia-inducible Factor 1α (HIF-1α) during Hypoxia
- (2011) Mikael Altun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIF-1α effects on angiogenic potential in human small cell lung carcinoma
- (2011) Jun Wan et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The metabolic advantage of tumor cells
- (2011) Maurice Israël et al. Molecular Cancer
- Hypoxia and Senescence: The Impact of Oxygenation on Tumor Suppression
- (2011) S. M. Welford et al. MOLECULAR CANCER RESEARCH
- Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element
- (2011) J Xu et al. ONCOGENE
- Synthesis of cytochrome c oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death
- (2011) C Wanka et al. ONCOGENE
- The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53–p21 axis
- (2011) J Pelletier et al. ONCOGENE
- Overexpression of the HIF Hydroxylases PHD1, PHD2, PHD3 and FIH Are Individually and Collectively Unfavorable Prognosticators for NSCLC Survival
- (2011) Sigve Andersen et al. PLoS One
- Systems Analysis of ATF3 in Stress Response and Cancer Reveals Opposing Effects on Pro-Apoptotic Genes in p53 Pathway
- (2011) Yujiro Tanaka et al. PLoS One
- Two-phase dynamics of p53 in the DNA damage response
- (2011) X.-P. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Frataxin participates to the hypoxia-induced response in tumors
- (2011) I Guccini et al. Cell Death & Disease
- Reciprocal influence of the p53 and the hypoxic pathways
- (2011) A Sermeus et al. Cell Death & Disease
- HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers
- (2010) Yoshifumi Baba et al. AMERICAN JOURNAL OF PATHOLOGY
- Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST
- (2010) C.-C. Tsai et al. BLOOD
- Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress: Role in the physiopathology of the disease
- (2010) Marielle Ousset et al. CELL CYCLE
- Autophagy in cancer associated fibroblasts promotes tumor cell survival
- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Role of autophagy in suppression of inflammation and cancer
- (2010) Eileen White et al. CURRENT OPINION IN CELL BIOLOGY
- Hypoxia and energetic tumour metabolism
- (2010) M Christiane Brahimi-Horn et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output
- (2010) Lihong Chen et al. EMBO JOURNAL
- Molecular markers associated with response to chemotherapy in gastro-entero-pancreatic neuroendocrine tumors
- (2010) Dermot O'Toole et al. ENDOCRINE-RELATED CANCER
- Renal Oxygenation Suppresses VHL Loss-Induced Senescence That Is Caused by Increased Sensitivity to Oxidative Stress
- (2010) S. M. Welford et al. MOLECULAR AND CELLULAR BIOLOGY
- mTORC1 Signaling under Hypoxic Conditions Is Controlled by ATM-Dependent Phosphorylation of HIF-1α
- (2010) Hakan Cam et al. MOLECULAR CELL
- The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
- (2010) Zhaohui Feng et al. TRENDS IN CELL BIOLOGY
- The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy
- (2009) E Y Tan et al. BRITISH JOURNAL OF CANCER
- Chemoradiation interactions under reduced oxygen conditions: Cellular characteristics of an in vitro model
- (2009) An Wouters et al. CANCER LETTERS
- Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors
- (2009) A.-T. Henze et al. CANCER RESEARCH
- Hypoxia-induced autophagy: cell death or cell survival?
- (2009) Nathalie M Mazure et al. CURRENT OPINION IN CELL BIOLOGY
- Kinases as Upstream Regulators of the HIF System: Their Emerging Potential as Anti-Cancer Drug Targets
- (2009) Elitsa Dimova et al. CURRENT PHARMACEUTICAL DESIGN
- Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer
- (2009) Abdullah Yalcin et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- HIF-1α Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms
- (2009) Alvaro Marin-Hernandez et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Cytoplasmic functions of the tumour suppressor p53
- (2009) Douglas R. Green et al. NATURE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
- (2009) G L Semenza ONCOGENE
- Targeting Hypoxia in Cancer Cells by Restoring Homeodomain Interacting Protein-Kinase 2 and p53 Activity and Suppressing HIF-1α
- (2009) Lavinia Nardinocchi et al. PLoS One
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Clinicopathologic significance of HIF-1α, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer
- (2008) Sung Yong Oh et al. BMC CANCER
- Poorer outcome in stromal HIF-2α- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis
- (2008) A H G Cleven et al. BRITISH JOURNAL OF CANCER
- p53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway
- (2008) N.V. Khromova et al. CANCER LETTERS
- ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer
- (2008) T. Migita et al. CANCER RESEARCH
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Tumor-associated Carbonic Anhydrase 9 Spatially Coordinates Intracellular pH in Three-dimensional Multicellular Growths
- (2008) Pawel Swietach et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p53 mRNA controls p53 activity by managing Mdm2 functions
- (2008) Marco M. Candeias et al. NATURE CELL BIOLOGY
- p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
- (2008) Keiko Kawauchi et al. NATURE CELL BIOLOGY
- Regulation of autophagy by cytoplasmic p53
- (2008) Ezgi Tasdemir et al. NATURE CELL BIOLOGY
- Transcriptional control of human p53-regulated genes
- (2008) Todd Riley et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chaperone-dependent stabilization and degradation of p53 mutants
- (2008) P Muller et al. ONCOGENE
- PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia
- (2008) G Xenaki et al. ONCOGENE
- New roles for pyruvate kinase M2: working out the Warburg effect
- (2008) Emily C. Ferguson et al. TRENDS IN BIOCHEMICAL SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started