标题
Necroptosis in Immuno-Oncology and Cancer Immunotherapy
作者
关键词
-
出版物
Cells
Volume 9, Issue 8, Pages 1823
出版商
MDPI AG
发表日期
2020-08-03
DOI
10.3390/cells9081823
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- RSV Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells
- (2020) Jennifer Simpson et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Regulated Necrosis in Pulmonary Disease: A Focus on Necroptosis and Ferroptosis
- (2020) Shunsuke Minagawa et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Clinical application of immune checkpoints in targeted immunotherapy of prostate cancer
- (2020) Sevda Jafari et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
- (2020) Tania Løve Aaes et al. JOURNAL OF IMMUNOLOGY
- Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5
- (2020) Yohei Ando et al. PLoS One
- Resistance to Checkpoint Inhibition in Cancer Immunotherapy
- (2020) Luisa Barrueto et al. Translational Oncology
- Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology
- (2020) Isaure Vanmeerbeek et al. OncoImmunology
- The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade
- (2020) Isobel S. Okoye et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer
- (2020) Yadong Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- Gut stem cell necroptosis by genome instability triggers bowel inflammation
- (2020) Ruicong Wang et al. NATURE
- Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
- (2020) Emma J. Petrie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
- (2020) Lorenzo Galluzzi et al. Journal for ImmunoTherapy of Cancer
- Necrotic cell death increases the release of Macrophage migration inhibitory factor (MIF) by monocytes/macrophages
- (2020) Wendy Dankers et al. IMMUNOLOGY AND CELL BIOLOGY
- Dendritic cell therapy in cancer treatment; the state-of-the-art
- (2020) Mahsa Sadeghzadeh et al. LIFE SCIENCES
- Establishing a Unified COVID-19 “Immunome”: Integrating Coronavirus Pathogenesis and Host Immunopathology
- (2020) Els Wauters et al. Frontiers in Immunology
- Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
- (2019) Jérôme Galon et al. NATURE REVIEWS DRUG DISCOVERY
- Combinatorial Approach to Improve Cancer Immunotherapy: Rational Drug Design Strategy to Simultaneously Hit Multiple Targets to Kill Tumor Cells and to Activate the Immune System
- (2019) Shweta Joshi et al. Journal of Oncology
- Regulatory T cells in cancer immunosuppression — implications for anticancer therapy
- (2019) Yosuke Togashi et al. Nature Reviews Clinical Oncology
- Death by inflammation: drug makers chase the master controller
- (2019) Cormac Sheridan NATURE BIOTECHNOLOGY
- Targeting RIPK1 in AML cells carrying FLT3‐ITD
- (2019) Laura K. Hillert et al. INTERNATIONAL JOURNAL OF CANCER
- TAK1 regulates endothelial cell necroptosis and tumor metastasis
- (2019) Lida Yang et al. CELL DEATH AND DIFFERENTIATION
- PGAM5-CypD pathway is involved in bromocriptine-induced RIP3/MLKL-dependent necroptosis of prolactinoma cells
- (2019) Shun-Li Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- The Coming Decade of Cell Death Research: Five Riddles
- (2019) Douglas R. Green CELL
- The molecular machinery of regulated cell death
- (2019) Daolin Tang et al. CELL RESEARCH
- Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
- (2019) Leonie Voorwerk et al. NATURE MEDICINE
- Resolvin D1 promotes the targeting and clearance of necroptotic cells
- (2019) Brennan D. Gerlach et al. CELL DEATH AND DIFFERENTIATION
- Biomarkers for Predicting Response to Immunotherapy with Immune Checkpoint Inhibitors in Cancer Patients
- (2019) Michael J. Duffy et al. CLINICAL CHEMISTRY
- Checkpoints inhibitors in the (neo)adjuvant setting of solid tumors
- (2019) Nuria Kotecki et al. CURRENT OPINION IN ONCOLOGY
- Combination of CTLA-4 and PD-1 blockers for treatment of cancer
- (2019) Anand Rotte JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Trial watch: dendritic cell vaccination for cancer immunotherapy
- (2019) Jenny Sprooten et al. OncoImmunology
- Macrophage-Mediated Subversion of Anti-Tumour Immunity
- (2019) Valeria Quaranta et al. Cells
- Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity
- (2019) Annelise G. Snyder et al. Science Immunology
- The role of pyroptosis in cancer: pro-cancer or pro-“host”?
- (2019) Xiaojing Xia et al. Cell Death & Disease
- RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
- (2019) Susana L. Orozco et al. Cell Reports
- Efficient engulfment of necroptotic and pyroptotic cells by nonprofessional and professional phagocytes
- (2019) Jiongcong Lu et al. Cell Discovery
- Myeloid immunosuppression and immune checkpoints in the tumor microenvironment
- (2019) Kyohei Nakamura et al. Cellular & Molecular Immunology
- Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4
- (2019) Shuang Qin et al. Molecular Cancer
- Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
- (2019) Melanie Fritsch et al. NATURE
- Molecular Insights into the Mechanism of Necroptosis: The Necrosome as a Potential Therapeutic Target
- (2019) Jing Chen et al. Cells
- Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway
- (2019) Justin S. A. Perry et al. NATURE CELL BIOLOGY
- Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine
- (2019) Victoria D. Turubanova et al. Journal for ImmunoTherapy of Cancer
- Necroptotic cancer cells-mimicry nanovaccine boosts anti-tumor immunity with tailored immune-stimulatory modality
- (2018) Ting Kang et al. BIOMATERIALS
- MLKL-PITPα signaling-mediated necroptosis contributes to cisplatin-triggered cell death in lung cancer A549 cells
- (2018) Lin Jing et al. CANCER LETTERS
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Necroptosis of tumor cells leads to tumor necrosis and promotes tumor metastasis
- (2018) Delong Jiao et al. CELL RESEARCH
- Low Necroptosis Process Predicts Poor Treatment Outcome of Human Papillomavirus Positive Cervical Cancers by Decreasing Tumor-Associated Macrophages M1 Polarization
- (2018) Lin Li et al. GYNECOLOGIC AND OBSTETRIC INVESTIGATION
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape
- (2018) Max D. Wellenstein et al. IMMUNITY
- Ablative Hypofractionated Radiation Therapy Enhances Non-Small Cell Lung Cancer Cell Killing via Preferential Stimulation of Necroptosis In Vitro and In Vivo
- (2018) Huan-Huan Wang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Critical Interactions between Immunogenic Cancer Cell Death, Oncolytic Viruses, and the Immune System Define the Rational Design of Combination Immunotherapies
- (2018) Jacob P. van Vloten et al. JOURNAL OF IMMUNOLOGY
- Necroptosis: a regulated inflammatory mode of cell death
- (2018) Yogesh K. Dhuriya et al. Journal of Neuroinflammation
- Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression
- (2018) Kezhou Zhu et al. Cell Death & Disease
- Epstein-Barr virus encoded latent membrane protein 1 suppresses necroptosis through targeting RIPK1/3 ubiquitination
- (2018) Xiaolan Liu et al. Cell Death & Disease
- Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC)
- (2018) Young Kwang Chae et al. Journal for ImmunoTherapy of Cancer
- High-mobility group box 1 protein-mediated necroptosis contributes to dasatinib-induced cardiotoxicity
- (2018) Zhifei Xu et al. TOXICOLOGY LETTERS
- Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis
- (2018) Miho Akimoto et al. Cell Death & Disease
- Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes
- (2018) Lien Van Hoecke et al. Nature Communications
- BRAF and AXL oncogenes drive RIPK3 expression loss in cancer
- (2018) Ayaz Najafov et al. PLOS BIOLOGY
- To the edge of cell death and back
- (2018) Yi-Nan Gong et al. FEBS Journal
- Cell death pathologies: targeting death pathways and the immune system for cancer therapy
- (2018) Francesca Pentimalli et al. GENES AND IMMUNITY
- Bypassing drug resistance by triggering necroptosis: recent advances in mechanisms and its therapeutic exploitation in leukemia
- (2018) Xianbo Huang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Identification and Characterization of NTB451 as a Potential Inhibitor of Necroptosis
- (2018) Eun-Jung In et al. MOLECULES
- Immune Checkpoints as Therapeutic Targets in Autoimmunity
- (2018) Christopher Paluch et al. Frontiers in Immunology
- Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells
- (2018) Anne-Kathrin Knuth et al. NEOPLASIA
- Second- and third-generation drugs for immuno-oncology treatment—The more the better?
- (2017) Wolfram C.M. Dempke et al. EUROPEAN JOURNAL OF CANCER
- Sequestering of damage-associated molecular patterns (DAMPs): a possible mechanism affecting the immune-stimulating properties of aluminium adjuvants
- (2017) Andreas Svensson et al. IMMUNOLOGIC RESEARCH
- Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses
- (2017) Abhishek D. Garg et al. IMMUNOLOGICAL REVIEWS
- Necroptotic cell death in anti-cancer therapy
- (2017) Olga Krysko et al. IMMUNOLOGICAL REVIEWS
- Co-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma
- (2017) Liliana E. Lucca et al. IMMUNOLOGICAL REVIEWS
- Caspase-8: regulating life and death
- (2017) Bart Tummers et al. IMMUNOLOGICAL REVIEWS
- Relevance of necroptosis in cancer
- (2017) Najoua Lalaoui et al. IMMUNOLOGY AND CELL BIOLOGY
- Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer
- (2017) Xuewei Zhang et al. MOLECULAR CANCER THERAPEUTICS
- An Inflammatory Perspective on Necroptosis
- (2017) Conor J. Kearney et al. MOLECULAR CELL
- Differential Induction of Immunogenic Cell Death and Interferon Expression in Cancer Cells by Structured ssRNAs
- (2017) Jaewoo Lee et al. MOLECULAR THERAPY
- A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
- (2017) Marta Łuksza et al. NATURE
- Necroptosis activation in Alzheimer's disease
- (2017) Antonella Caccamo et al. NATURE NEUROSCIENCE
- Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
- (2017) Stephanie A. Conos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape
- (2017) Abhishek D. Garg et al. TRENDS IN IMMUNOLOGY
- Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis
- (2017) Kelby W. Wegner et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis
- (2017) Chengkui Yang et al. Cell Death & Disease
- RIPK3 promotes adenovirus type 5 activity
- (2017) Melanie Weigert et al. Cell Death & Disease
- RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function
- (2017) Kay Hänggi et al. Cell Death & Disease
- Silver nanoparticles of different sizes induce a mixed type of programmed cell death in human pancreatic ductal adenocarcinoma
- (2017) Ewelina Zielinska et al. Oncotarget
- Phosphatidylserine externalization, “necroptotic bodies” release, and phagocytosis during necroptosis
- (2017) Sefi Zargarian et al. PLOS BIOLOGY
- Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells
- (2017) Haley L. Peters et al. Cancer Immunology Research
- Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma
- (2017) Abhishek D. Garg et al. OncoImmunology
- Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine
- (2016) Gabriel Moreno-Gonzalez et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing
- (2016) W. G. Land et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma
- (2016) Kevin D. McCormick et al. CARCINOGENESIS
- Evolutionary divergence of the necroptosis effector MLKL
- (2016) M C Tanzer et al. CELL DEATH AND DIFFERENTIATION
- Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation
- (2016) A D Garg et al. CELL DEATH AND DIFFERENTIATION
- A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis
- (2016) Katharina Rohde et al. CELL DEATH AND DIFFERENTIATION
- Do not let death do us part: ‘find-me’ signals in communication between dying cells and the phagocytes
- (2016) C B Medina et al. CELL DEATH AND DIFFERENTIATION
- Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration
- (2016) Zhenyu Cai et al. CELL RESEARCH
- MLKL forms cation channels
- (2016) Bingqing Xia et al. CELL RESEARCH
- Poly-ubiquitination in TNFR1-mediated necroptosis
- (2016) Yves Dondelinger et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Biomarkers for the detection of necroptosis
- (2016) Sudan He et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Bortezomib Treatment Sensitizes Oncolytic HSV-1-Treated Tumors to NK Cell Immunotherapy
- (2016) J. Y. Yoo et al. CLINICAL CANCER RESEARCH
- The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
- (2016) Lena Seifert et al. NATURE
- Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
- (2016) Boris Strilic et al. NATURE
- Keratin mediates the recognition of apoptotic and necrotic cells through dendritic cell receptor DEC205/CD205
- (2016) Longxing Cao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade glioma
- (2016) Abhishek D. Garg et al. Science Translational Medicine
- Association of Mixed Lineage Kinase Domain-Like Protein Expression With Prognosis in Patients With Colon Cancer
- (2016) Xian Li et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- Prognostic value of mixed lineage kinase domain-like protein expression in the survival of patients with gastric caner
- (2016) Zhai Ertao et al. TUMOR BIOLOGY
- Post-translational modifications as key regulators of TNF-induced necroptosis
- (2016) X Liu et al. Cell Death & Disease
- Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis
- (2016) Dominique Bozec et al. Oncotarget
- Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
- (2016) Tania Løve Aaes et al. Cell Reports
- Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy
- (2016) Heng Yang et al. OncoImmunology
- Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G
- (2016) Sareetha Kailayangiri et al. OncoImmunology
- Antitumor Immunity Triggered by Melphalan Is Potentiated by Melanoma Cell Surface-Associated Calreticulin
- (2015) A. M. Dudek-Peri et al. CANCER RESEARCH
- RIP1 Kinase Is an Oncogenic Driver in Melanoma
- (2015) X. Y. Liu et al. CANCER RESEARCH
- Regulation of RIPK1's cell death function by phosphorylation
- (2015) Yves Dondelinger et al. CELL CYCLE
- Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production
- (2015) C J Kearney et al. CELL DEATH AND DIFFERENTIATION
- Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis
- (2015) D A Rodriguez et al. CELL DEATH AND DIFFERENTIATION
- Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics
- (2015) Gi-Bang Koo et al. CELL RESEARCH
- Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals
- (2015) M. N. McCracken et al. CLINICAL CANCER RESEARCH
- Regulation of inflammasome activation
- (2015) Si Ming Man et al. IMMUNOLOGICAL REVIEWS
- Necroptotic cells release find-me signal and are engulfed without proinflammatory cytokine production
- (2015) Qiang Wang et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Tumor neoantigens: building a framework for personalized cancer immunotherapy
- (2015) Matthew M. Gubin et al. JOURNAL OF CLINICAL INVESTIGATION
- Apoptosis, autophagy, necroptosis, and cancer metastasis
- (2015) Zhenyi Su et al. Molecular Cancer
- Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy
- (2015) Shabnam Shalapour et al. NATURE
- Phagocytosis of apoptotic cells in homeostasis
- (2015) Sanja Arandjelovic et al. NATURE IMMUNOLOGY
- Combination cancer immunotherapies tailored to the tumour microenvironment
- (2015) Mark J. Smyth et al. Nature Reviews Clinical Oncology
- Big opportunities for small molecules in immuno-oncology
- (2015) Jerry L. Adams et al. NATURE REVIEWS DRUG DISCOVERY
- Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death
- (2015) B Schenk et al. ONCOGENE
- RIPK1 and NF- B signaling in dying cells determines cross-priming of CD8+ T cells
- (2015) N. Yatim et al. SCIENCE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Targeting apoptosis for anticancer therapy
- (2015) Simone Fulda SEMINARS IN CANCER BIOLOGY
- An Apoptotic ‘Eat Me’ Signal: Phosphatidylserine Exposure
- (2015) Katsumori Segawa et al. TRENDS IN CELL BIOLOGY
- New immunotherapies targeting the PD-1 pathway
- (2015) Jordan M. Chinai et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway
- (2015) Zahra Shahsavari et al. TUMOR BIOLOGY
- Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production
- (2015) Xinfang Yu et al. Oncotarget
- RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1α release, and efficient paracrine dendritic cell activation
- (2015) Susanne V. Schmidt et al. Oncotarget
- Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death
- (2015) Abhishek D. Garg et al. Frontiers in Immunology
- DAMPs from Cell Death to New Life
- (2015) Emilie Vénéreau et al. Frontiers in Immunology
- Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma
- (2015) Lien Vandenberk et al. OncoImmunology
- RIPK3—a predictive marker for personalized immunotherapy?
- (2015) Sigrun Smola OncoImmunology
- Classification of current anticancer immunotherapies
- (2015) Lorenzo Galluzzi et al. Oncotarget
- RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
- (2014) Christopher P. Dillon et al. CELL
- Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic ‘eat-me’ signals: cleavage and inhibition of phagocytosis by Lp-PLA2
- (2014) V A Tyurin et al. CELL DEATH AND DIFFERENTIATION
- Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death
- (2014) J. M. Murphy et al. EMBO REPORTS
- Responses of macrophages to the danger signals released from necrotic cells
- (2014) T. Kimura et al. INTERNATIONAL IMMUNOLOGY
- Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death
- (2014) Carolien A. Koks et al. INTERNATIONAL JOURNAL OF CANCER
- High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
- (2014) Carsten Linnemann et al. NATURE MEDICINE
- Regulated necrosis: the expanding network of non-apoptotic cell death pathways
- (2014) Tom Vanden Berghe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Receptor Interactive Protein Kinase 3 Promotes Cisplatin-Triggered Necrosis in Apoptosis-Resistant Esophageal Squamous Cell Carcinoma Cells
- (2014) Yang Xu et al. PLoS One
- Molecular mechanisms of regulated necrosis
- (2014) Lorenzo Galluzzi et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
- (2014) Q Remijsen et al. Cell Death & Disease
- RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage
- (2014) A-L Nugues et al. Cell Death & Disease
- Necroptosis induced by RIPK3 requires MLKL but not Drp1
- (2014) D M Moujalled et al. Cell Death & Disease
- MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
- (2014) Yves Dondelinger et al. Cell Reports
- Cancer immunogenicity, danger signals, and DAMPs: What, when, and how?
- (2013) Abhishek D. Garg et al. BIOFACTORS
- The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis
- (2013) Zeze Fu et al. BMC CANCER
- Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma
- (2013) Lauren E. Colbert et al. CANCER
- Oxygen regulates molecular mechanisms of cancer progression and metastasis
- (2013) Kartik Gupta et al. CANCER AND METASTASIS REVIEWS
- The mechanism of necroptosis in normal and cancer cells
- (2013) Simone Fulda CANCER BIOLOGY & THERAPY
- Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor
- (2013) Dagmar Schumacher et al. CANCER CELL
- Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments
- (2013) H Inoue et al. CELL DEATH AND DIFFERENTIATION
- Antigen Availability Determines CD8+ T Cell-Dendritic Cell Interaction Kinetics and Memory Fate Decisions
- (2013) Sarah E. Henrickson et al. IMMUNITY
- Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
- (2013) Gabriela Bindea et al. IMMUNITY
- Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance
- (2013) Agnieszka Kaczmarek et al. IMMUNITY
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells
- (2013) C-Y Huang et al. Cell Death & Disease
- Many faces of DAMPs in cancer therapy
- (2013) O Krysko et al. Cell Death & Disease
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
- (2012) Jixi Li et al. CELL
- F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells
- (2012) Susan Ahrens et al. IMMUNITY
- Serum Lactate Dehydrogenase Predicts for Overall Survival Benefit in Patients With Metastatic Renal Cell Carcinoma Treated With Inhibition of Mammalian Target of Rapamycin
- (2012) Andrew J. Armstrong et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
- (2012) Shigeki Chiba et al. NATURE IMMUNOLOGY
- The secret ally: immunostimulation by anticancer drugs
- (2012) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Fueling the Flames: Mammalian Programmed Necrosis in Inflammatory Diseases
- (2012) F. K.-M. Chan Cold Spring Harbor Perspectives in Biology
- Primary sterile necrotic cells fail to cross-prime CD8+T cells
- (2012) Jaba Gamrekelashvili et al. OncoImmunology
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The prognostic value of histological tumor necrosis in solid organ malignant disease: a systematic review
- (2011) Colin H Richards et al. Future Oncology
- Beginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways
- (2011) Kodi S. Ravichandran IMMUNITY
- Cell Death in the Maintenance and Abrogation of Tolerance: The Five Ws of Dying Cells
- (2011) Thomas S. Griffith et al. IMMUNITY
- RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
- (2011) Linde Duprez et al. IMMUNITY
- The innate immune system and the clearance of apoptotic cells
- (2011) Andrew Devitt et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Caspase 8 inhibits programmed necrosis by processing CYLD
- (2011) Marie Anne O’Donnell et al. NATURE CELL BIOLOGY
- Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis
- (2011) P Bist et al. ONCOGENE
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
- (2011) Craig H Mermel et al. GENOME BIOLOGY
- Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells
- (2010) Christoph Peter et al. APOPTOSIS
- Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation
- (2010) N Hiraoka et al. BRITISH JOURNAL OF CANCER
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums
- (2010) Kodi S. Ravichandran JOURNAL OF EXPERIMENTAL MEDICINE
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Differential release of chromatin-bound IL-1 discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
- (2010) I. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Receptor Interacting Protein 1 Inhibits p53 Induction through NF- B Activation and Confers a Worse Prognosis in Glioblastoma
- (2009) S. Park et al. CANCER RESEARCH
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Antigenic profiles of individual-matched pairs of primary and melanoma metastases
- (2009) Clifton B. Meije et al. HUMAN PATHOLOGY
- Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways
- (2009) Karine Lolmede et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
- (2009) David Sancho et al. NATURE
- The Inflammatory Response to Cell Death
- (2008) Kenneth L. Rock et al. Annual Review of Pathology-Mechanisms of Disease
- Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
- (2008) Stefan Schütze et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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