RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

(2014) K. Newton et al.   SCIENCE

Necroptosis induced by RIPK3 requires MLKL but not Drp1

(2014) D M Moujalled et al.   Cell Death & Disease

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY

RIP3 Finds Partners in Crime

(2012) Francis Ka-Ming Chan et al.   CELL

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

Identification of an N-terminal Truncation of the NF-κB p65 Subunit That Specifically Modulates Ribosomal Protein S3-dependent NF-κB Gene Expression

(2012) Eric M. Wier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family

(2012) N Skrypek et al.   ONCOGENE

Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1

(2011) P Liu et al.   LEUKEMIA

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

(2011) S Löder et al.   LEUKEMIA

Caspase 8 inhibits programmed necrosis by processing CYLD

(2011) Marie Anne O’Donnell et al.   NATURE CELL BIOLOGY

GILZ inhibits the mTORC2/AKT pathway in BCR-ABL+ cells

(2011) S Joha et al.   ONCOGENE

Mutant nucleophosmin deregulates cell death and myeloid differentiation through excessive caspase-6 and -8 inhibition

(2010) S. M. Leong et al.   BLOOD

Tyrosine Phosphorylation Is Required for IκB Kinase-β (IKKβ) Activation and Function in Osteoclastogenesis

(2010) Isra Darwech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression

(2010) S. L. Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes

(2008) Mayte Coiras et al.   Retrovirology