标题
Strategies in Translating the Therapeutic Potentials of Host Defense Peptides
作者
关键词
-
出版物
Frontiers in Immunology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-05-22
DOI
10.3389/fimmu.2020.00983
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Functional Characterization of a Novel Hybrid Peptide with High Potency against Gram-negative Bacteria
- (2020) Yara Al Tall et al. CURRENT PHARMACEUTICAL DESIGN
- Antimicrobial host defence peptides: functions and clinical potential
- (2020) Neeloffer Mookherjee et al. NATURE REVIEWS DRUG DISCOVERY
- Conversion of Broad-Spectrum Antimicrobial Peptides into Species-Specific Antimicrobials Capable of Precisely Targeting Pathogenic Bacteria
- (2020) Lin Xu et al. Scientific Reports
- Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?
- (2020) Marlon H. Cardoso et al. Frontiers in Microbiology
- Nanoantibiotics containing membrane-active human cathelicidin LL-37 or synthetic ceragenins attached to the surface of magnetic nanoparticles as novel and innovative therapeutic tools: current status and potential future applications
- (2020) Urszula Wnorowska et al. JOURNAL OF NANOBIOTECHNOLOGY
- Search for Shorter Portions of the Proline-Rich Antimicrobial Peptide Fragment Bac5(1-25) That Retain Antimicrobial Activity by Blocking Protein Synthesis
- (2019) Mario Mardirossian et al. ChemMedChem
- Reassessing the Host Defense Peptide Landscape
- (2019) Evan F. Haney et al. Frontiers in Chemistry
- Unifying structural signature of eukaryotic α-helical host defense peptides
- (2019) Nannette Y. Yount et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Melittin: from honeybees to superbugs
- (2019) Hamed Memariani et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Hybrids made from antimicrobial peptides with different mechanisms of action show enhanced membrane permeabilization
- (2019) Heidi M. Wade et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Plant defensins: types, mechanism of action and prospects of genetic engineering for enhanced disease resistance in plants
- (2019) Raham Sher Khan et al. 3 Biotech
- Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens
- (2019) Biswajit Mishra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KR-12-a5 Reverses Adverse Effects of Lipopolysaccharides on HBMSC Osteogenic Differentiation by Influencing BMP/Smad and P38 MAPK Signaling Pathways
- (2019) Hui Li et al. Frontiers in Pharmacology
- Rational Design of Hybrid Peptides: A Novel Drug Design Approach
- (2019) Chao Wang et al. Current Medical Science
- Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model
- (2019) Jayaram Lakshmaiah Narayana et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Artificial intelligence-assisted telemedicine platform for cataract screening and management: a potential model of care for global eye health
- (2019) Darren Shu Jeng Ting et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Antiviral Activities of Human Host Defense Peptides
- (2019) David C. Brice et al. CURRENT MEDICINAL CHEMISTRY
- Non-Lytic Antibacterial Peptides That Translocate Through Bacterial Membranes to Act on Intracellular Targets
- (2019) Marlon H. Cardoso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cathelicidin-Derived Synthetic Peptide Improves Therapeutic Potential of Vancomycin Against Pseudomonas aeruginosa
- (2019) Imran Mohammed et al. Frontiers in Microbiology
- Combinatory Therapy Antimicrobial Peptide-Antibiotic to Minimize the Ongoing Rise of Resistance
- (2019) Luis R. Pizzolato-Cezar et al. Frontiers in Microbiology
- Proline‐Rich Peptides with Improved Antimicrobial Activity against E. coli , K. pneumoniae , and A. baumannii
- (2019) Mario Mardirossian et al. ChemMedChem
- KR‑12‑a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling
- (2019) Lanqing Fu et al. Molecular Medicine Reports
- Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance
- (2019) Réka Spohn et al. Nature Communications
- Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs
- (2019) Alexandra Brakel et al. Frontiers in Chemistry
- Development of a novel hybrid antimicrobial peptide for targeted killing of Pseudomonas aeruginosa
- (2019) Hyun Kim et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The History of Nanoscience and Nanotechnology: From Chemical–Physical Applications to Nanomedicine
- (2019) Samer Bayda et al. MOLECULES
- Rethinking drug design in the artificial intelligence era
- (2019) Petra Schneider et al. NATURE REVIEWS DRUG DISCOVERY
- The antimicrobial peptide ZY4 combats multidrug-resistantPseudomonas aeruginosaandAcinetobacter baumanniiinfection
- (2019) James Mwangi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action
- (2019) Bálint Kintses et al. Nature Communications
- Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions
- (2019) Nigare Raheem et al. Frontiers in Microbiology
- Fragments of the non-lytic proline-rich antimicrobial peptide Bac5 kill E. coli cells by inhibiting protein synthesis.
- (2018) Mario Mardirossian et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Arg/Trp-Rich Cyclic α/β-Antimicrobial Peptides: The Roles of H-bonding and Hydrophobic/Hydrophilic Solvent Accessible Surface Areas upon the Activity and Membrane Selectivity
- (2018) Mojtaba Bagheri et al. CHEMISTRY-A EUROPEAN JOURNAL
- Engineered Nanoparticles with Antimicrobial Property
- (2018) Veliyath Gopi Reshma et al. CURRENT DRUG METABOLISM
- A 10-year analysis of microbiological profiles of microbial keratitis: the North East England Study
- (2018) Darren Shu Jeng Ting et al. EYE
- Polymicrobial Keratitis With Cryptococcus curvatus, Candida parapsilosis, and Stenotrophomonas maltophilia After Penetrating Keratoplasty
- (2018) Darren Shu Jeng Ting et al. Eye & Contact Lens-Science and Clinical Practice
- Antimicrobial Peptides: Features, Action, and Their Resistance Mechanisms in Bacteria
- (2018) Hoda Moravej et al. Microbial Drug Resistance
- The Road from Host-Defense Peptides to a New Generation of Antimicrobial Drugs
- (2018) Alicia Boto et al. MOLECULES
- Tryptophan-Rich and Proline-Rich Antimicrobial Peptides
- (2018) Awdhesh Mishra et al. MOLECULES
- Exploring the role of unnatural amino acids in antimicrobial peptides
- (2018) Rosario Oliva et al. Scientific Reports
- Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens
- (2018) Rajamani Lakshminarayanan et al. Advanced Healthcare Materials
- Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges
- (2018) Lubhandwa S. Biswaro et al. Frontiers in Microbiology
- New Insights Into the Mechanisms and Biological Roles of D-Amino Acids in Complex Eco-Systems
- (2018) Alena Aliashkevich et al. Frontiers in Microbiology
- Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides
- (2018) Ammar Almaaytah et al. Infection and Drug Resistance
- Atomistic-Level Investigation of a LL37-Conjugated Gold Nanoparticle By Well-Tempered Metadynamics
- (2018) André F. Ferreira et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Toward the Synthesis and Improved Biopotential of an N-methylated Analog of a Proline-Rich Cyclic Tetrapeptide from Marine Bacteria
- (2018) Rajiv Dahiya et al. Marine Drugs
- Nano based drug delivery systems: recent developments and future prospects
- (2018) Jayanta Kumar Patra et al. JOURNAL OF NANOBIOTECHNOLOGY
- Antimicrobial Peptides: the Achilles’ Heel of Antibiotic Resistance?
- (2018) Angélique Lewies et al. Probiotics and Antimicrobial Proteins
- The Persistent Dilemma of Microbial Keratitis: Global Burden, Diagnosis, and Antimicrobial Resistance
- (2018) Lawson Ung et al. SURVEY OF OPHTHALMOLOGY
- LL-37-derived short antimicrobial peptide KR-12-a5 and its d -amino acid substituted analogs with cell selectivity, anti-biofilm activity, synergistic effect with conventional antibiotics, and anti-inflammatory activity
- (2017) Eun Young Kim et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Daptomycin
- (2017) Mohsen Heidary et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential
- (2017) Michela Comune et al. JOURNAL OF CONTROLLED RELEASE
- Artificial intelligence in medicine
- (2017) Pavel Hamet et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics
- (2017) Annarita Falanga et al. MOLECULES
- Antimicrobial activity of a new synthetic peptide loaded in polylactic acid or poly(lactic-co-glycolic) acid nanoparticles against Pseudomonas aeruginosa, Escherichia coli O157:H7 and methicillin resistant Staphylococcus aureus (MRSA)
- (2017) J Cruz et al. NANOTECHNOLOGY
- Proline-rich antimicrobial peptides targeting protein synthesis
- (2017) Michael Graf et al. NATURAL PRODUCT REPORTS
- Human antimicrobial peptides in ocular surface defense
- (2017) Imran Mohammed et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Nanoparticles: Properties, applications and toxicities
- (2017) Ibrahim Khan et al. Arabian Journal of Chemistry
- Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications
- (2017) Berthony Deslouches et al. Oncotarget
- Few novel antibiotics in the pipeline, WHO warns
- (2017) Zosia Kmietowicz BMJ-British Medical Journal
- Few novel antibiotics in the pipeline, WHO warns
- (2017) Zosia Kmietowicz BMJ-British Medical Journal
- The Naturally Occurring Host Defense Peptide, LL-37, and Its Truncated Mimetics KE-18 and KR-12 Have Selected Biocidal and Antibiofilm Activities Against Candida albicans, Staphylococcus aureus, and Escherichia coli In vitro
- (2017) Yu Luo et al. Frontiers in Microbiology
- Combination Strategies to Enhance the Efficacy of Antimicrobial Peptides against Bacterial Biofilms
- (2017) Lucia Grassi et al. Frontiers in Microbiology
- Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design
- (2017) Jianguo Li et al. Frontiers in Neuroscience
- Antimicrobial Peptides in Biomedical Device Manufacturing
- (2017) Martijn Riool et al. Frontiers in Chemistry
- Differential stability of therapeutic peptides with different proteolytic cleavage sites in blood, plasma and serum
- (2017) Roland Böttger et al. PLoS One
- Highly potent antimicrobial peptides from N-terminal membrane-binding region of E. coli MreB
- (2017) Karabi Saikia et al. Scientific Reports
- D-form KLKLLLLLKLK-NH2 peptide exerts higher antimicrobial properties than its L-form counterpart via an association with bacterial cell wall components
- (2017) Takayuki Manabe et al. Scientific Reports
- Host Cell Interactions Are a Significant Barrier to the Clinical Utility of Peptide Antibiotics
- (2016) Charles G. Starr et al. ACS Chemical Biology
- Improving short antimicrobial peptides despite elusive rules for activity
- (2016) Ralf Mikut et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The effect of amidation on the behaviour of antimicrobial peptides
- (2016) Manuela Mura et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Antimicrobial peptides and wound healing: biological and therapeutic considerations
- (2016) Maria Luisa Mangoni et al. EXPERIMENTAL DERMATOLOGY
- Peptides with 6-Aminohexanoic Acid: Synthesis and Evaluation as Plasmin Inhibitors
- (2016) Maciej Purwin et al. International Journal of Peptide Research and Therapeutics
- Understanding the mechanisms and drivers of antimicrobial resistance
- (2016) Alison H Holmes et al. LANCET
- Enhancement of the antimicrobial activity and selectivity of GNU7 against Gram-negative bacteria by fusion with LPS-targeting peptide
- (2016) Hyun Kim et al. PEPTIDES
- Mapping membrane activity in undiscovered peptide sequence space using machine learning
- (2016) Ernest Y. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria
- (2016) Rajamani Lakshminarayanan et al. Scientific Reports
- Antimicrobial Peptides: An Emerging Category of Therapeutic Agents
- (2016) Margit Mahlapuu et al. Frontiers in Cellular and Infection Microbiology
- Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus
- (2016) Mohamed F. Mohamed et al. Scientific Reports
- Antimicrobial Peptide CMA3 Derived from the CA-MA Hybrid Peptide: Antibacterial and Anti-inflammatory Activities with Low Cytotoxicity and Mechanism of Action in Escherichia coli
- (2015) Jong-kook Lee et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phospholipid-driven differences determine the action of the synthetic antimicrobial peptide OP-145 on Gram-positive bacterial and mammalian membrane model systems
- (2015) Nermina Malanovic et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool
- (2015) Francesco Salvatore et al. International Journal of Nanomedicine
- Analysis of the flexibility and stability of the structure of magainin in a bilayer, and in aqueous and nonaqueous solutions using molecular dynamics simulations
- (2015) Elham Esmaili et al. JOURNAL OF MOLECULAR MODELING
- Deep learning
- (2015) Yann LeCun et al. NATURE
- APD3: the antimicrobial peptide database as a tool for research and education
- (2015) Guangshun Wang et al. NUCLEIC ACIDS RESEARCH
- Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase
- (2014) Chiara Falciani et al. AMINO ACIDS
- High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments
- (2014) Guangshun Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing
- (2014) Kiran Kumar Chereddy et al. JOURNAL OF CONTROLLED RELEASE
- Design, characterization and expression of a novel hybrid peptides melittin (1–13)-LL37 (17–30)
- (2014) Rujuan Wu et al. MOLECULAR BIOLOGY REPORTS
- iAMP-2L: A two-level multi-label classifier for identifying antimicrobial peptides and their functional types
- (2013) Xuan Xiao et al. ANALYTICAL BIOCHEMISTRY
- Rational Design of Engineered Cationic Antimicrobial Peptides Consisting Exclusively of Arginine and Tryptophan, and Their Activity against Multidrug-Resistant Pathogens
- (2013) Berthony Deslouches et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Peptide design for antimicrobial and immunomodulatory applications
- (2013) Evan F. Haney et al. BIOPOLYMERS
- Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity
- (2013) Binu Jacob et al. JOURNAL OF PEPTIDE SCIENCE
- Antimicrobial peptides stage a comeback
- (2013) Jeffrey L Fox NATURE BIOTECHNOLOGY
- LAMP: A Database Linking Antimicrobial Peptides
- (2013) Xiaowei Zhao et al. PLoS One
- A Proline-Hinge Alters the Characteristics of the Amphipathic α-helical AMPs
- (2013) Jong Kook Lee et al. PLoS One
- Improved Protease Stability of the Antimicrobial Peptide Pin2 Substituted with d-Amino Acids
- (2013) G. Carmona et al. PROTEIN JOURNAL
- Binding and reorientation of melittin in a POPC bilayer: Computer simulations
- (2012) Sheeba J. Irudayam et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Therapeutic Potential of Host Defense Peptides in Antibiotic-resistant Infections
- (2012) Nicole J. Afacan et al. CURRENT PHARMACEUTICAL DESIGN
- Exploring bioactive peptides from natural sources for oxytocin and vasopressin drug discovery
- (2012) Christian W Gruber et al. Future Medicinal Chemistry
- Ab Initio Design of Potent Anti-MRSA Peptides Based on Database Filtering Technology
- (2012) Biswajit Mishra et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II
- (2012) Marc A. Fox et al. PEPTIDES
- Structural and Functional Characterization of a Multifunctional Alanine-Rich Peptide Analogue from Pleuronectes americanus
- (2012) Ludovico Migliolo et al. PLoS One
- Evolutionary Trade-Offs, Pareto Optimality, and the Geometry of Phenotype Space
- (2012) O. Shoval et al. SCIENCE
- Influence of C-Terminal Amidation on the Efficacy of Modelin-5
- (2011) Sarah R. Dennison et al. BIOCHEMISTRY
- Structure, Dynamics, and Antimicrobial and Immune Modulatory Activities of Human LL-23 and Its Single-Residue Variants Mutated on the Basis of Homologous Primate Cathelicidins
- (2011) Guangshun Wang et al. BIOCHEMISTRY
- Structural basis for the enhanced activity of cyclic antimicrobial peptides: The case of BPC194
- (2011) Jacek T. Mika et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children: Executive Summary
- (2011) Catherine Liu et al. CLINICAL INFECTIOUS DISEASES
- More effective antimicrobial mastoparan derivatives, generated by 3D-QSAR-Almond and computational mutagenesis
- (2011) Speranta Avram et al. Molecular BioSystems
- Gold nanoparticles: preparation, properties, and applications in bionanotechnology
- (2011) Yi-Cheun Yeh et al. Nanoscale
- Designing antimicrobial peptides: form follows function
- (2011) Christopher D. Fjell et al. NATURE REVIEWS DRUG DISCOVERY
- Wound healing activity of the human antimicrobial peptide LL37
- (2011) Reinaldo Ramos et al. PEPTIDES
- The expanding scope of antimicrobial peptide structures and their modes of action
- (2011) Leonard T. Nguyen et al. TRENDS IN BIOTECHNOLOGY
- Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
- (2011) Hirenkumar K. Makadia et al. Polymers
- Influence of N-terminus modifications on the biological activity, membrane interaction, and secondary structure of the antimicrobial peptide hylin-a1
- (2010) Edson Crusca et al. BIOPOLYMERS
- Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens
- (2010) Daniel Knappe et al. JOURNAL OF MEDICINAL CHEMISTRY
- Origins and Evolution of Antibiotic Resistance
- (2010) J. Davies et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Esculentin 1-21: a linear antimicrobial peptide from frog skin with inhibitory effect on bovine mastitis-causing bacteria
- (2009) Alfonso Enrique Islas-Rodrìguez et al. JOURNAL OF PEPTIDE SCIENCE
- Molecular Interactions between Magainin 2 and Model Membranes in Situ
- (2009) Khoi Tan Nguyen et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Use of Artificial Intelligence in the Design of Small Peptide Antibiotics Effective against a Broad Spectrum of Highly Antibiotic-Resistant Superbugs
- (2008) Artem Cherkasov et al. ACS Chemical Biology
- Structure, membrane orientation, mechanism, and function of pexiganan — A highly potent antimicrobial peptide designed from magainin
- (2008) Lindsey M. Gottler et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Topical versus Systemic Antimicrobial Therapy for Treating Mildly Infected Diabetic Foot Ulcers: A Randomized, Controlled, Double‐Blinded, Multicenter Trial of Pexiganan Cream
- (2008) Benjamin A. Lipsky et al. CLINICAL INFECTIOUS DISEASES
- NMR of Membrane-Associated Peptides and Proteins
- (2008) Guangshun Wang CURRENT PROTEIN & PEPTIDE SCIENCE
- Structural Determinants of Antimicrobial and Antiplasmodial Activity and Selectivity in Histidine-rich Amphipathic Cationic Peptides
- (2008) A. James Mason et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structures of Human Host Defense Cathelicidin LL-37 and Its Smallest Antimicrobial Peptide KR-12 in Lipid Micelles
- (2008) Guangshun Wang JOURNAL OF BIOLOGICAL CHEMISTRY
- Study of the mechanism of action of anoplin, a helical antimicrobial decapeptide with ion channel-like activity, and the role of the amidatedC-terminus
- (2007) Marcia Perez Dos Santos Cabrera et al. JOURNAL OF PEPTIDE SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now