Article
Infectious Diseases
Tanya Trinh, Seema Emami, Jonah Gould, Michael Mimouni, Eyal Cohen, David S. Rootman, Allan R. Slomovic, Clara C. Chan
Summary: This study reported the characteristics and outcomes of fungal keratitis in Toronto, Canada over a 20-year period. Candida was the most frequent pathogen in the region, with risk factors for poor outcomes including low visual acuity, previous corneal transplantation, and topical steroid use.
Article
Ophthalmology
Rakhi Kusumesh, Anita Ambastha, Lalan K. Arya, Anita Kumari, Neha Kumari, Bibhuti P. Sinha, Nilesh Mohan, Namrata Kumari
Summary: This retrospective study analyzed the clinical and microbiological data of 2303 non-viral MK patients in Bihar, India from 2019 to 2022. The study revealed that MK is a significant cause of ocular morbidity in Bihar, with male predominance, corneal injury being the major risk factor, and fungal infection being the most common causative organism.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Darren Shu Jeng Ting, Charlotte Shan Ho, Jessica Cairns, Bhavesh P. Gopal, Ahmad Elsahn, Mouhamed Al-Aqaba, Tim Boswell, Dalia G. Said, Harminder S. Dua
Summary: The study examined seasonal patterns, demographic factors, and microbiological profiles of infectious keratitis in Nottingham, UK. While the overall incidence of infectious keratitis was similar among all four seasons, there was a significant increase in cases during the summer over the past decade. This seasonal variation may be attributed to factors such as contact lens wear, increased outdoor/water activities, and warmer temperatures conducive to microbial growth.
Article
Ophthalmology
Malik Moledina, Harry W. Roberts, Achyut Mukherjee, David Spokes, Dimitris Pimenides, Christopher Stephenson, Ramy Bassily, Madhavan S. Rajan, James Myerscough
Summary: This study analyzed the incidence, microbiological profile, and antimicrobial susceptibilities of microbial keratitis (MK) in the East of England over a 6-year period. The most common pathogen was Pseudomonas spp. Gram-positive and gram-negative bacteria showed similar proportions among culture-positive cases. The majority of isolates were susceptible to penicillin classes, fluoroquinolones, and aminoglycosides, but there was an increasing resistance to cephalosporins among gram-negative bacteria.
Article
Microbiology
Nischal Ranganath, Joshua D. Shirley, Douglas W. Challener, Ryan W. Stevens, Dalton R. Kind, Isin Y. Comba, Robin Patel, Audrey N. Schuetz, Aditya S. Shah
Summary: Leptotrichia species are increasingly recognized as pathogens capable of causing invasive infections, especially among immunocompromised patients. However, there is limited data on the epidemiology, antimicrobial susceptibility, treatment, and clinical outcomes of Leptotrichia bacteremia. Evaluation of patient risk factors, treatment approaches, and outcomes, as well as examination of Leptotrichia isolates over the past decade, provided important insights. Evaluation of antimicrobial susceptibility testing is crucial due to evolving resistance patterns.
JOURNAL OF CLINICAL MICROBIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Louise Hayes, Tim Cheetham, Colin Muirhead, Neil Hopper, Judith Reid, William Lamb, Jenny Foster, Richard J. Q. Mcnally
Summary: This study examined the incidence of type 1 diabetes in children aged 0-14 years in the North East of England and North Cumbria from 2012 to 2020. The findings suggest a potential decrease in the incidence of type 1 diabetes in this region. The reasons for this decline are unclear and further research is needed to understand the underlying factors.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Ophthalmology
Yamini Tawde, Shreya Singh, Sourav Das, Shivaprakash Rudramurthy, Harsimran Kaur, Amit Gupta, Mounjuri Kataki, Pranami Gogoi, Anup Ghosh
Summary: This study investigated the clinical presentation, etiological agents, and risk factors of fungal keratitis (FK) cases in two tertiary-care centers in India. The results showed regional differences in the causative agents of FK and highlighted the importance of identifying the ecological niche of potential fungal pathogens.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Correction
Multidisciplinary Sciences
Aris Konstantopoulos, Maria del Mar Cendra, Michael Tsatsos, Mariam Elabiary, Myron Christodoulides, Parwez Hossain
Summary: The paper has been amended and the amended version can be accessed through the link at the top of the paper.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Supriya Sharma, Srikant K. Sahu, Suryasnata Rath, Aparajita Mallick, Savitri Sharma, Sujata Das
Summary: The study revealed that most patients with infectious keratitis and nasolacrimal duct obstruction were infected by gram-positive bacteria, with Streptococcus pneumoniae, coagulase-negative Staphylococcus, and Staphylococcus aureus being the most common. These bacteria showed varying degrees of susceptibility to antibiotics such as ciprofloxacin, ofloxacin, gatifloxacin, and moxifloxacin.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Sloan W. Rush, Blaze Bulla, Ryan B. Rush
Summary: Overall, patients who underwent penetrating keratoplasty (PK) secondary to complications related to contact lens use had worse visual outcomes at 2 years compared to those related to LASIK. The complications leading to PK were rare in both cohorts, but the incidence of undergoing PK secondary to contact lens use trended slightly higher than LASIK.
JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Immunology
Richard Harris
Summary: This study analyzed a (population weighted) sample of 4533 responses to a household survey conducted in March 2021 on the impact of COVID-19 on residents in the North East of England. The results showed that factors such as age, socioeconomic status, ethnicity, and religious beliefs were important in determining willingness to undergo testing, self-isolation, and vaccine hesitancy. Future vaccination and 'track and trace' programs may need to consider these factors for better effectiveness.
Article
Environmental Sciences
Aurora Ghirardelli, Stefan Otto, Roberta Masin, Cristian Bano, Lorenzo Altissimo, Sonia Russo, Giuseppe Zanin
Summary: The study focused on the trends of atrazine, terbuthylazine, deethyl-atrazine, and deethyl-terbuthylazine concentrations in the aquifer north of Vicenza, Italy, from 1987 to 2016. It found that all pollutants showed decreasing concentrations over the 30-year monitoring period, with terbuthylazine and deethyl-terbuthylazine consistently lower than atrazine and deethyl-atrazine, respectively.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Oncology
Pere Roura, Emma Puigoriol, Jacint Altimiras, Eduard Batiste-Alentorn, Irene R. Degano
Summary: This study aimed to analyze the trends in cancer incidence and 1-year mortality in northeastern Spain from 2005 to 2020. The results showed an increasing incidence of colorectal, lung and bronchus, and urinary bladder cancer in females, while the incidence of stomach and prostate cancer decreased in males. The 1-year mortality rates decreased for endometrium cancer in females and colorectal cancer in males. The study also found a decrease in cancer incidence and an increase in mortality rate as a result of the COVID-19 pandemic.
Article
Ophthalmology
Darren Shu Jeng Ting, Charlotte Shan Ho, Jessica Cairns, Ahmad Elsahn, Mouhamed Al-Aqaba, Tim Boswell, Dalia G. Said, Harminder Singh Dua
Summary: Infectious keratitis (IK) is a relatively common and underestimated burden in Nottingham, UK, with Gram-positive and Gram-negative bacteria, especially Pseudomonas aeruginosa being the most commonly isolated pathogens. Current broad-spectrum antimicrobial treatment provides good coverage for IK, although some level of antimicrobial resistance and polymicrobial infections pose challenges.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Agronomy
Alice Kuenzel, Sandra Muenzel, Falk Boettcher, Daniel Spengler
Summary: Winter wheat is the most important crop in Germany, and a three-year field trial in Brandenburg investigated the effects of weather on biometric parameters of different winter wheat varieties. The study found that there were hardly any differences between winter wheat varieties in dry years, but irrigation significantly increased grain yields. Multiple regression analysis showed a strong correlation between the biometric parameters considered and the grain yield.
