Review: The Tumor-Like Phenotype of Rheumatoid Synovium: Molecular Profiling and Prospects for Precision Medicine

Phosphoproteome analysis of synoviocytes from patients with rheumatoid arthritis

(2017) Masayoshi Katano et al.   International Journal of Rheumatic Diseases

CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression

(2017) Yanxia Guo et al.   JOURNAL OF IMMUNOLOGY

Why location matters — site-specific factors in rheumatic diseases

(2017) Caroline Ospelt et al.   Nature Reviews Rheumatology

The role of metabolism in the pathogenesis of osteoarthritis

(2017) Ali Mobasheri et al.   Nature Reviews Rheumatology

Synovial tissue research: a state-of-the-art review

(2017) Carl Orr et al.   Nature Reviews Rheumatology

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions

(2017) Mojca Frank-Bertoncelj et al.   Nature Communications

Protective effect of low dose intra-articular cadmium on inflammation and joint destruction in arthritis

(2017) Paola Bonaventura et al.   Scientific Reports

Synovial Immunophenotype and Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis Patients

(2017) Carl Orr et al.   Arthritis & Rheumatology

Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis

(2017) Evangelos Ntougkos et al.   Arthritis & Rheumatology

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis

(2017) Ivy Y. Choi et al.   PLoS One

Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis

(2017) Trudy McGarry et al.   Scientific Reports

Dysregulated bioenergetics: a key regulator of joint inflammation

(2016) M Biniecka et al.   ANNALS OF THE RHEUMATIC DISEASES

GC/TOF-MS-based metabolomic profiling in cultured fibroblast-like synoviocytes from rheumatoid arthritis

(2016) Joong Kyong Ahn et al.   JOINT BONE SPINE

Liposomal Treatment of Experimental Arthritis Can Be Monitored Noninvasively with a Radiolabeled Anti–Fibroblast Activation Protein Antibody

(2016) Tessa van der Geest et al.   JOURNAL OF NUCLEAR MEDICINE

GREM1 Is a Key Regulator of Synoviocyte Hyperplasia and Invasiveness

(2016) E.-J. Han et al.   JOURNAL OF RHEUMATOLOGY

MIFallele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis

(2016) Seung-Ah Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

(2016) Rizi Ai et al.   Nature Communications

Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes

(2016) Ricard Garcia-Carbonell et al.   Arthritis & Rheumatology

Review: Preclinical Rheumatoid Arthritis: Progress Toward Prevention

(2016) Kulveer Mankia et al.   Arthritis & Rheumatology

A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis

(2016) Nan Mu et al.   Scientific Reports

MiRNA-203 suppresses cell proliferation, migration and invasion in colorectal cancer via targeting of EIF5A2

(2016) Biao Deng et al.   Scientific Reports

miR-203 inhibits melanoma invasive and proliferative abilities by targeting the polycomb group gene BMI1

(2015) Xiao Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Contribution of synovial lining cells to synovial vascularization of the rat temporomandibular joint

(2015) Kayoko Nozawa-Inoue et al.   JOURNAL OF ANATOMY

Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti-Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis

(2015) P. Laverman et al.   JOURNAL OF NUCLEAR MEDICINE

Downregulation of microRNA-221 decreases migration and invasion in fibroblast-like synoviocytes in rheumatoid arthritis

(2015) SHUZHONG YANG et al.   Molecular Medicine Reports

Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets

(2015) John W. Whitaker et al.   PLoS One

Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism

(2015) Erika H Noss et al.   ARTHRITIS RESEARCH & THERAPY

Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis

(2015) Trudy McGarry et al.   ARTHRITIS RESEARCH & THERAPY

DNA Methylome Signature in Synoviocytes From Patients With Early Rheumatoid Arthritis Compared to Synoviocytes From Patients With Longstanding Rheumatoid Arthritis

(2015) Rizi Ai et al.   Arthritis & Rheumatology

The Rheumatoid Arthritis Risk GeneLBHRegulates Growth in Fibroblast-like Synoviocytes

(2015) Anna-Karin H. Ekwall et al.   Arthritis & Rheumatology

Stromal Transcriptional Profiles Reveal Hierarchies of Anatomical Site, Serum Response and Disease and Identify Disease Specific Pathways

(2015) Andrew Filer et al.   PLoS One

Cell cycle regulation therapy combined with cytokine blockade enhances antiarthritic effects without increasing immune suppression

(2014) Tadashi Hosoya et al.   ANNALS OF THE RHEUMATIC DISEASES

Choline kinase inhibition in rheumatoid arthritis

(2014) M Guma et al.   ANNALS OF THE RHEUMATIC DISEASES

Cadherin-11 mRNA transcripts are frequently found in rheumatoid arthritis peripheral blood and correlate with established polyarthritis

(2014) P.P. Sfikakis et al.   CLINICAL IMMUNOLOGY

Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner

(2014) Kalle Sipilä et al.   FASEB JOURNAL

Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors

(2014) C. Sekine et al.   JOURNAL OF IMMUNOLOGY

miR-203 Suppresses the Proliferation and Migration and Promotes the Apoptosis of Lung Cancer Cells by Targeting SRC

(2014) Nan Wang et al.   PLoS One

Mitochondrial dysfunction promotes and aggravates the inflammatory response in normal human synoviocytes

(2014) Marta N. Valcárcel-Ares et al.   RHEUMATOLOGY

Inhibition of Spermidine/Spermine N1-Acetyltransferase Activity: A New Therapeutic Concept in Rheumatoid Arthritis

(2014) Michel Neidhart et al.   Arthritis & Rheumatology

Ultrasound colour Doppler is associated with synovial pathology in biopsies from hand joints in rheumatoid arthritis patients: a cross-sectional study

(2013) Martin Andersen et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis

(2013) Rachel Knevel et al.   ANNALS OF THE RHEUMATIC DISEASES

The Impact of Inflammation on Metabolomic Profiles in Patients With Arthritis

(2013) Stephen P. Young et al.   ARTHRITIS AND RHEUMATISM

Avastin Exhibits Therapeutic Effects on Collagen-Induced Arthritis in Rat Model

(2013) Yong Wang et al.   INFLAMMATION

MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma

(2013) Guangyi Zhao et al.   PLoS One

Identification of key regulators for the migration and invasion of rheumatoid synoviocytes through a systems approach

(2013) S. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype

(2013) John W Whitaker et al.   Genome Medicine

Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model

(2012) Ioannis Pandis et al.   ANNALS OF THE RHEUMATIC DISEASES

DNA methylome signature in rheumatoid arthritis

(2012) Kazuhisa Nakano et al.   ANNALS OF THE RHEUMATIC DISEASES

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance

(2011) F. Niederer et al.   ANNALS OF THE RHEUMATIC DISEASES

Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis

(2011) M. Trenkmann et al.   ANNALS OF THE RHEUMATIC DISEASES

Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis

(2011) Monika Biniecka et al.   ARTHRITIS AND RHEUMATISM

Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis

(2011) Jelena Vojinovic et al.   ARTHRITIS AND RHEUMATISM

Disorders in angiogenesis and redox pathways are main factors contributing to the progression of rheumatoid arthritis: A comparative proteomics study

(2011) Jian-Guang Wang et al.   ARTHRITIS AND RHEUMATISM

Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

(2011) Emmanuel Karouzakis et al.   ARTHRITIS AND RHEUMATISM

miR221/222 in Cancer: Their Role in Tumor Progression and Response to Therapy

(2011) M. Garofalo et al.   CURRENT MOLECULAR MEDICINE

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts

(2011) E Karouzakis et al.   GENES AND IMMUNITY

Unknown

(2011) Leo Joosten et al.   MOLECULAR MEDICINE

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angiogenesis and blood vessel stability in inflammatory arthritis

(2010) Aisling Kennedy et al.   ARTHRITIS AND RHEUMATISM

Effectiveness of radiation synovectomy with Yttrium-90 and Samarium-153 particulate hydroxyapatite in rheumatoid arthritis patients with knee synovitis: a controlled, randomized, double-blinded trial

(2010) Marla Francisca dos Santos et al.   CLINICAL RHEUMATOLOGY

The rheumatoid arthritis HLA–DRB1 shared epitope

(2010) Joseph Holoshitz   CURRENT OPINION IN RHEUMATOLOGY

Epigenetics and rheumatoid arthritis: The role of SENP1 in the regulation of MMP-1 expression

(2010) Hanna Maciejewska-Rodrigues et al.   JOURNAL OF AUTOIMMUNITY

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis

(2010) Tomoko Kawabata et al.   ARTHRITIS RESEARCH & THERAPY

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

(2009) Emmanuel Karouzakis et al.   ARTHRITIS AND RHEUMATISM

Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: A link between angiogenesis and inflammation

(2009) Seung-Ah Yoo et al.   ARTHRITIS AND RHEUMATISM

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Immature Blood Vessels in Rheumatoid Synovium Are Selectively Depleted in Response to Anti-TNF Therapy

(2009) Elena Izquierdo et al.   PLoS One

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

(2008) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Methylation status of a single CpG site in theIL6promoter is related toIL6messenger RNA levels and rheumatoid arthritis

(2008) Christoper J. Nile et al.   ARTHRITIS AND RHEUMATISM

Analyses of differential proteome of human synovial fibroblasts obtained from arthritis

(2008) Gan-Ping Bo et al.   CLINICAL RHEUMATOLOGY

Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

(2008) X. Agirre et al.   MOLECULAR CANCER RESEARCH