Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis

Tissue inhibitor of metalloproteinase-3 (TIMP3) promotes endothelial apoptosis via a caspase-independent mechanism

(2015) Jian Hua Qi et al.   APOPTOSIS

α2 Integrin, extracellular matrix metalloproteinase inducer, and matrix metalloproteinase-3 act sequentially to induce differentiation of mouse embryonic stem cells into odontoblast-like cells

(2015) Nobuaki Ozeki et al.   EXPERIMENTAL CELL RESEARCH

High threshold of β1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2)

(2014) Kulrut Borrirukwanit et al.   Cancer Cell International

Cutting Edge: TLR2 Is a Functional Receptor for Acute-Phase Serum Amyloid A

(2014) N. Cheng et al.   JOURNAL OF IMMUNOLOGY

Activation of Matrix Metalloproteinases 2, 9, and 13 by Activated Protein C in Human Osteoarthritic Cartilage Chondrocytes

(2014) Miriam T. Jackson et al.   Arthritis & Rheumatology

Tissue Inhibitor of Metalloproteinases–3 Moderates the Proinflammatory Status of Macrophages

(2013) Sean E. Gill et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Toll-like receptor activation and mechanical force stimulation promote the secretion of matrix metalloproteinases 1, 3 and 10 of human periodontal fibroblasts via p38, JNK and NF-kB

(2013) Rodolfo Assis Lisboa et al.   ARCHIVES OF ORAL BIOLOGY

M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway

(2013) Chao-Ying Liu et al.   LABORATORY INVESTIGATION

Microcalcifications in breast cancer: novel insights into the molecular mechanism and functional consequence of mammary mineralisation

(2012) R F Cox et al.   BRITISH JOURNAL OF CANCER

α11β1 integrin-mediated MMP-13-dependent collagen lattice contraction by fibroblasts: Evidence for integrin-coordinated collagen proteolysis

(2012) Malgorzata M. Barczyk et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Acute serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis

(2011) M. Connolly et al.   ANNALS OF THE RHEUMATIC DISEASES

The pattern-recognition receptor nucleotide-binding oligomerization domain-containing protein 1 promotes production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts

(2011) Kazuhiro Yokota et al.   ARTHRITIS AND RHEUMATISM

Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy

(2011) Mary Connolly et al.   ARTHRITIS AND RHEUMATISM

The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis

(2011) Marvin A. Peters et al.   ARTHRITIS AND RHEUMATISM

TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes

(2011) L. Philippe et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptor 2 Induced Angiogenesis and Invasion Is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis

(2011) Tajvur Saber et al.   PLoS One

Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

(2011) Sinéad Nic An Ultaigh et al.   ARTHRITIS RESEARCH & THERAPY

Cooperation of TLR2 with MyD88, PI3K, and Rac1 in Lipoteichoic Acid–Induced cPLA2/COX-2–Dependent Airway Inflammatory Responses

(2010) I-Ta Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration

(2010) K. Grote et al.   BLOOD

Toll-Like Receptor 2- and MyD88-Dependent Phosphatidylinositol 3-Kinase and Rac1 Activation Facilitates the Phagocytosis of Listeria monocytogenes by Murine Macrophages

(2010) Y. Shen et al.   INFECTION AND IMMUNITY

Leptospira santorosaiSerovar Shermani Detergent Extract Induces an Increase in Fibronectin Production through a Toll-Like Receptor 2-Mediated Pathway

(2010) Ya-Chung Tian et al.   INFECTION AND IMMUNITY

Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

(2010) Xiaoxia Z. West et al.   NATURE

Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB-dependent activation of the urokinase plasminogen activator system

(2009) S D Killeen et al.   BRITISH JOURNAL OF CANCER

Toll-Like Receptor-2 Mediates Inflammation and Matrix Degradation in Human Atherosclerosis

(2009) Claudia Monaco et al.   CIRCULATION

Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling

(2009) Q.-Q. Huang et al.   JOURNAL OF IMMUNOLOGY

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer

(2009) L. A. J. O'Neill et al.   PHARMACOLOGICAL REVIEWS

A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin

(2008) Gisa Gerold et al.   NATURE IMMUNOLOGY