The Pathogenesis of Rheumatoid Arthritis

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice

(2011) Stephan Blüml et al.   ARTHRITIS AND RHEUMATISM

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

(2011) Andreas Hess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis

(2011) M. Kurowska-Stolarska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Catecholamine-producing cells in the synovial tissue during arthritis: modulation of sympathetic neurotransmitters as new therapeutic target

(2010) S. Capellino et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis

(2010) Natalia Wegner et al.   ARTHRITIS AND RHEUMATISM

Neutrophils in rheumatoid arthritis: More than simple final effectors

(2010) R. Cascão et al.   AUTOIMMUNITY REVIEWS

Immune Dysregulation by the Rheumatoid Arthritis Shared Epitope

(2010) D. E. De Almeida et al.   JOURNAL OF IMMUNOLOGY

Membrane-Type I Matrix Metalloproteinase-Dependent Regulation of Rheumatoid Arthritis Synoviocyte Function

(2010) F. Sabeh et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium

(2010) A. J. Hueber et al.   JOURNAL OF IMMUNOLOGY

Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006

(2010) M. E. Holmqvist et al.   JOURNAL OF INTERNAL MEDICINE

An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis

(2010) Michael E. Weinblatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence for a functional role of IgE anticitrullinated protein antibodies in rheumatoid arthritis

(2010) A. J. M. Schuerwegh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis

(2009) M J L Peters et al.   ANNALS OF THE RHEUMATIC DISEASES

Interpreting lipid levels in the context of high-grade inflammatory states with a focus on rheumatoid arthritis: a challenge to conventional cardiovascular risk actions

(2009) E Choy et al.   ANNALS OF THE RHEUMATIC DISEASES

Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis

(2009) Tineke Cantaert et al.   ARTHRITIS AND RHEUMATISM

The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo

(2009) Joel M. Kremer et al.   ARTHRITIS AND RHEUMATISM

Microanatomic studies to define predictive factors for the topography of periarticular erosion formation in inflammatory arthritis

(2009) Dennis McGonagle et al.   ARTHRITIS AND RHEUMATISM

Osteoclasts and Arthritis

(2009) Georg Schett et al.   JOURNAL OF BONE AND MINERAL RESEARCH

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

(2009)   LANCET

Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

(2009) Hiba Mahdi et al.   NATURE GENETICS

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Role for TNF in atherosclerosis? Lessons from autoimmune disease

(2009) Gayle E. McKellar et al.   Nature Reviews Cardiology

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

(2009) Ann L. Cornish et al.   Nature Reviews Rheumatology

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE

Rheumatoid Arthritis Synovium Contains Two Subsets of CD83−DC-LAMP− Dendritic Cells with Distinct Cytokine Profiles

(2008) M. Cristina Lebre et al.   AMERICAN JOURNAL OF PATHOLOGY

Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints

(2008) K Polzer et al.   ANNALS OF THE RHEUMATIC DISEASES

Changes in hand and generalised bone mineral density in patients with recent-onset rheumatoid arthritis

(2008) M Guler-Yuksel et al.   ANNALS OF THE RHEUMATIC DISEASES

MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial (CIMESTRA)

(2008) M L Hetland et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunity to Citrullinated Proteins in Rheumatoid Arthritis

(2008) Lars Klareskog et al.   Annual Review of Immunology

How antirheumatic drugs protect joints from damage in rheumatoid arthritis

(2008) Georg Schett et al.   ARTHRITIS AND RHEUMATISM

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

(2008) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Spleen tyrosine kinase: a novel target for therapeutic intervention of rheumatoid arthritis

(2008) Malini Bajpai et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Therapeutic targeting of Janus kinases

(2008) Marko Pesu et al.   IMMUNOLOGICAL REVIEWS

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis

(2008) Allison L Smitten et al.   ARTHRITIS RESEARCH & THERAPY