Synovial Immunophenotype and Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis Patients

Patients with seronegative RA have more inflammatory activity compared with patients with seropositive RA in an inception cohort of DMARD-naïve patients classified according to the 2010 ACR/EULAR criteria

(2016) Lena Bugge Nordberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis

(2016) Nida Meednu et al.   Arthritis & Rheumatology

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

(2015) Akilan Krishnamurthy et al.   ANNALS OF THE RHEUMATIC DISEASES

Peripheral CD4CD8 Double Positive T Cells with a Distinct Helper Cytokine Profile Are Increased in Rheumatoid Arthritis

(2014) Dagmar Quandt et al.   PLoS One

High expression levels of the B cell chemoattractant CXCL13 in rheumatoid synovium are a marker of severe disease

(2014) Serena Bugatti et al.   RHEUMATOLOGY

CXCL13 predicts disease activity in early rheumatoid arthritis and could be an indicator of the therapeutic `window of opportunity'

(2014) Stinne Ravn Greisen et al.   ARTHRITIS RESEARCH & THERAPY

The cellular composition of lymph nodes in the earliest phase of inflammatory arthritis

(2013) L G M van Baarsen et al.   ANNALS OF THE RHEUMATIC DISEASES

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

(2013) Khaled Amara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differences in synovial fluid cytokine levels but not in synovial tissue cell infiltrate between anti-citrullinated peptide/protein antibody-positive and –negative rheumatoid arthritis patients

(2013) José A Gómez-Puerta et al.   ARTHRITIS RESEARCH & THERAPY

Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis: Implications for Understanding Preclinical Rheumatoid Arthritis

(2013) M. J. H. de Hair et al.   Arthritis & Rheumatology

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

(2012) Ulrike Harre et al.   JOURNAL OF CLINICAL INVESTIGATION

The influence of ACPA status and characteristics on the course of RA

(2012) Annemiek Willemze et al.   Nature Reviews Rheumatology

Tumor necrosis factor blocking therapy alters joint inflammation and hypoxia

(2011) Aisling Kennedy et al.   ARTHRITIS AND RHEUMATISM

High Levels of Anti-Cyclic Citrullinated Peptide Autoantibodies Are Associated with Co-occurrence of Pulmonary Diseases with Rheumatoid Arthritis

(2011) F. AUBART et al.   JOURNAL OF RHEUMATOLOGY

Should Anti-citrullinated Protein Antibody and Rheumatoid Factor Status Be Reassessed During the First Year of Followup in Recent-Onset Arthritis? A Longitudinal Study

(2011) M. D. MJAAVATTEN et al.   JOURNAL OF RHEUMATOLOGY

Presence of lymphocyte aggregates in the synovium of patients with early arthritis in relationship to diagnosis and outcome: is it a constant feature over time?

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

The value of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: Do they imply new risk factors?

(2010) F.J. Lopez-Longo et al.   DRUG NEWS & PERSPECTIVES

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: Results from two large early arthritis cohorts

(2009) Diane van der Woude et al.   ARTHRITIS AND RHEUMATISM

Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis

(2009) Tineke Cantaert et al.   ARTHRITIS AND RHEUMATISM

The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid arthritis: A prospective study

(2009) Ruth Klaasen et al.   ARTHRITIS AND RHEUMATISM

Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers

(2009) B. BRESNIHAN et al.   JOURNAL OF RHEUMATOLOGY

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE

The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor   expression in the synovium

(2007) C A Wijbrandts et al.   ANNALS OF THE RHEUMATIC DISEASES