Human Neurospheroid Arrays for In Vitro Studies of Alzheimer’s Disease

Stop Alzheimer’s before it starts

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Assembly of functionally integrated human forebrain spheroids

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Three-Dimensional Models of the Human Brain Development and Diseases

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Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics

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The modeling of Alzheimer's disease by the overexpression of mutant Presenilin 1 in human embryonic stem cells

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Selective and effective targeting of chronic myeloid leukemia stem cells by topoisomerase II inhibitor etoposide in combination with imatinib mesylate in vitro

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Stem Cell Models of Human Brain Development

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Dishing out mini-brains: Current progress and future prospects in brain organoid research

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Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

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The promises and challenges of human brain organoids as models of neuropsychiatric disease

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Building brains in a dish: Prospects for growing cerebral organoids from stem cells

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Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1

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Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer’s Disease Mutations

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Three Dimensional Human Neuro-Spheroid Model of Alzheimer’s Disease Based on Differentiated Induced Pluripotent Stem Cells

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Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

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Alzheimer's in 3D culture: Challenges and perspectives

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The genetic landscape of Alzheimer disease: clinical implications and perspectives

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Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease

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A 3D human neural cell culture system for modeling Alzheimer's disease

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Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer

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Three-Dimensional Neural Spheroid Culture: AnIn VitroModel for Cortical Studies

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APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons

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Networked neural spheroid by neuro-bundle mimicking nervous system created by topology effect

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Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9

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Drug discovery through stem cell-based organoid models

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The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

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Stem cell derived basal forebrain cholinergic neurons from Alzheimer’s disease patients are more susceptible to cell death

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A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors

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Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

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The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

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iPSCs to the Rescue in Alzheimer's Research

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Alzheimer's disease in a dish: promises and challenges of human stem cell models

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Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

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Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research

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Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events

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Cognitive Decline in Prodromal Alzheimer Disease and Mild Cognitive Impairment

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Neurotoxicity of methotrexate to hippocampal cells in vivo and in vitro

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Development and Evolution of the Human Neocortex

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Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells

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Self-formation of functional adenohypophysis in three-dimensional culture

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A neurospheroid network-stamping method for neural transplantation to the brain

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Controlled-size embryoid body formation in concave microwell arrays

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Folate antagonist, methotrexate induces neuronal differentiation of human embryonic stem cells transplanted into nude mouse retina

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Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

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Animal models of Alzheimer's disease and frontotemporal dementia

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