Chronotherapy with conventional blood pressure medications improves management of hypertension and reduces cardiovascular and stroke risks

Ambulatory Blood Pressure Monitoring (ABPM) asTHEreference standard to confirm diagnosis of hypertension in adults: Recommendation of the 2015 U.S. Preventive Services Task Force (USPSTF)

(2015) Michael H. Smolensky et al.   CHRONOBIOLOGY INTERNATIONAL

Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea

(2015) Alexandros Kasiakogias et al.   JOURNAL OF HYPERTENSION

Time of administration important? Morning versus evening dosing of valsartan

(2015) Dion H. Zappe et al.   JOURNAL OF HYPERTENSION

2015 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the Management of Hypertension

(2015) Chern-En Chiang et al.   Journal of the Chinese Medical Association

Chronotherapeutics of Conventional Blood Pressure-Lowering Medications: Simple, Low-Cost Means of Improving Management and Treatment Outcomes of Hypertensive-Related Disorders

(2014) Ramón C. Hermida et al.   CURRENT HYPERTENSION REPORTS

Bedtime Hypertension Chronotherapy: Concepts and Patient Outcomes

(2014) Michael Smolensky et al.   CURRENT PHARMACEUTICAL DESIGN

Targeting Nocturnal Hypertension in Type 2 Diabetes Mellitus

(2014) Niklas Blach Rossen et al.   HYPERTENSION

Evening Dosing of Antihypertensive Therapy to Reduce Cardiovascular Events: A Third Type of Evidence Based on a Systematic Review and Meta-Analysis of Randomized Trials

(2014) George C. Roush et al.   Journal of Clinical Hypertension

Sleep-time ambulatory blood pressure as a novel therapeutic target for cardiovascular risk reduction

(2014) R C Hermida et al.   JOURNAL OF HUMAN HYPERTENSION

Prognostic impact from clinic, daytime, and night-time systolic blood pressure in nine cohorts of 13 844 patients with hypertension

(2014) George C. Roush et al.   JOURNAL OF HYPERTENSION

Switching therapy to bedtime for uncontrolled hypertension with a nondipping pattern

(2013) Raymond Farah et al.   BLOOD PRESSURE MONITORING

2013 Ambulatory Blood Pressure Monitoring Recommendations for the Diagnosis of Adult Hypertension, Assessment of Cardiovascular and other Hypertension-associated Risk, and Attainment of Therapeutic Goals

(2013) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

(2013)   EUROPEAN HEART JOURNAL

The possibility of resistant hypertension during the treatment of hypertensive patients

(2013) Tetsuo Nishikawa et al.   HYPERTENSION RESEARCH

Nifedipine controlled-release 40 mg b.i.d. in Japanese patients with essential hypertension who responded insufficiently to nifedipine controlled-release 40 mg q.d.: a phase III, randomized, double-blind and parallel-group study

(2013) Kazuaki Shimamoto et al.   HYPERTENSION RESEARCH

2013 ESH/ESC Guidelines for the management of arterial hypertension

(2013) Giuseppe Mancia et al.   JOURNAL OF HYPERTENSION

Chronotherapy improves blood pressure control and reduces vascular risk in CKD

(2013) Ramón C. Hermida et al.   Nature Reviews Nephrology

Abnormalities in chronic kidney disease of ambulatory blood pressure 24 h patterning and normalization by bedtime hypertension chronotherapy

(2013) R. C. Hermida et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Blunted Sleep-Time Relative Blood Pressure Decline Increases Cardiovascular Risk Independent of Blood Pressure Level—The “Normotensive Non-dipper” Paradox

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Role of Time-of-Day of Hypertension Treatment on the J-Shaped Relationship Between Blood Pressure and Cardiovascular Risk

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Comparison of Ambulatory Blood Pressure Parameters of Hypertensive Patients With and Without Chronic Kidney Disease

(2012) Artemio Mojón et al.   CHRONOBIOLOGY INTERNATIONAL

Administration-Time-Dependent Effects of Hypertension Treatment on Ambulatory Blood Pressure in Patients With Chronic Kidney Disease

(2012) Juan J. Crespo et al.   CHRONOBIOLOGY INTERNATIONAL

Cardiovascular Risk of Essential Hypertension: Influence of Class, Number, and Treatment-Time Regimen of Hypertension Medications

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Dipper and Non-Dipper Blood Pressure 24-Hour Patterns: Circadian Rhythm–Dependent Physiologic and Pathophysiologic Mechanisms

(2012) Fabio Fabbian et al.   CHRONOBIOLOGY INTERNATIONAL

Ambulatory Blood Pressure Monitoring: Importance of Sampling Rate and Duration—48 Versus 24 Hours—on the Accurate Assessment of Cardiovascular Risk

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Effects of Time-of-Day of Hypertension Treatment on Ambulatory Blood Pressure and Clinical Characteristics of Patients With Type 2 Diabetes

(2012) Ana Moyá et al.   CHRONOBIOLOGY INTERNATIONAL

Sleep-Time Blood Pressure: Prognostic Value and Relevance as a Therapeutic Target for Cardiovascular Risk Reduction

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Circadian Variations in Exsorptive Transport: In Situ Intestinal Perfusion Data and In Vivo Relevance

(2012) Alper Okyar et al.   CHRONOBIOLOGY INTERNATIONAL

Clinical Application of a Novel Automatic Algorithm for Actigraphy-Based Activity and Rest Period Identification to Accurately Determine Awake and Asleep Ambulatory Blood Pressure Parameters and Cardiovascular Risk

(2012) Cristina Crespo et al.   CHRONOBIOLOGY INTERNATIONAL

Prevalence and Clinical Characteristics of Isolated-Office and True Resistant Hypertension Determined by Ambulatory Blood Pressure Monitoring

(2012) María T. Ríos et al.   CHRONOBIOLOGY INTERNATIONAL

Circadian Pattern of Ambulatory Blood Pressure in Hypertensive Patients With and Without Type 2 Diabetes

(2012) Diana E. Ayala et al.   CHRONOBIOLOGY INTERNATIONAL

Cardiovascular Risk of Resistant Hypertension: Dependence on Treatment-Time Regimen of Blood Pressure–Lowering Medications

(2012) Diana E. Ayala et al.   CHRONOBIOLOGY INTERNATIONAL

Influence of Age and Hypertension Treatment-time on Ambulatory Blood Pressure in Hypertensive Patients

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Administration-Time Differences in Effects of Hypertension Medications on Ambulatory Blood Pressure Regulation

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Treatment-Time Regimen of Hypertension Medications Significantly Affects Ambulatory Blood Pressure and Clinical Characteristics of Patients With Resistant Hypertension

(2012) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

A Bedtime Dose of ARB Was Better than a Morning Dose in Improving Baroreflex Sensitivity and Urinary Albumin Excretion—The J-TOP Study

(2012) Kazuo Eguchi et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

A Trial of 2 Strategies to Reduce Nocturnal Blood Pressure in Blacks With Chronic Kidney Disease

(2012) Mahboob Rahman et al.   HYPERTENSION

Effect of Valsartan With Bedtime Dosing on Chronic Kidney Disease Patients With Nondipping Blood Pressure Pattern

(2012) Cheng Wang et al.   Journal of Clinical Hypertension

Automatic identification of activity–rest periods based on actigraphy

(2012) Cristina Crespo et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Timing to Perfection: The Biology of Central and Peripheral Circadian Clocks

(2012) Urs Albrecht   NEURON

Notice

(2012)   Kidney International Supplements

Sleep-Time Blood Pressure and the Prognostic Value of Isolated-Office and Masked Hypertension

(2011) Ramón C. Hermida et al.   AMERICAN JOURNAL OF HYPERTENSION

Sleep-Time Blood Pressure as a Therapeutic Target for Cardiovascular Risk Reduction in Type 2 Diabetes

(2011) Ramón C. Hermida et al.   AMERICAN JOURNAL OF HYPERTENSION

Prognostic Role of Ambulatory Blood Pressure Measurement in Patients With Nondialysis Chronic Kidney Disease

(2011) Roberto Minutolo et al.   ARCHIVES OF INTERNAL MEDICINE

Chronotherapy With Valsartan/Hydrochlorothiazide Combination in Essential Hypertension: Improved Sleep-Time Blood Pressure Control With Bedtime Dosing

(2011) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Influence of Time of Day of Blood Pressure-Lowering Treatment on Cardiovascular Risk in Hypertensive Patients With Type 2 Diabetes

(2011) R. C. Hermida et al.   DIABETES CARE

Standards of Medical Care in Diabetes--2012

(2011)   DIABETES CARE

Fixed-combination of amlodipine and diuretic chronotherapy in the treatment of essential hypertension: improved blood pressure control with bedtime dosing—a multicenter, open-label randomized study

(2011) Jing Zeng et al.   HYPERTENSION RESEARCH

Sleep-Time Blood Pressure

(2011) Alan H. Gradman   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Decreasing Sleep-Time Blood Pressure Determined by Ambulatory Monitoring Reduces Cardiovascular Risk

(2011) Ramón C. Hermida et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Bedtime Dosing of Antihypertensive Medications Reduces Cardiovascular Risk in CKD

(2011) R. C. Hermida et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effects of chronotherapy on blood pressure control in non-dipper patients with refractory hypertension

(2011) J. Almirall et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Circadian rhythms and cardiovascular health

(2011) Francesco Portaluppi et al.   SLEEP MEDICINE REVIEWS

Effects of combination therapy with amlodipine and fosinopril administered at different times on blood pressure and circadian blood pressure pattern in patients with essential hypertension

(2010) Y. Meng et al.   ACTA CARDIOLOGICA

Circadian Rhythms in Blood Pressure Regulation and Optimization of Hypertension Treatment With ACE Inhibitor and ARB Medications

(2010) R. C. Hermida et al.   AMERICAN JOURNAL OF HYPERTENSION

Administration–time-dependent effects of blood pressure-lowering medications: basis for the chronotherapy of hypertension

(2010) Michael H. Smolensky et al.   BLOOD PRESSURE MONITORING

PERSPECTIVES ON THE CHRONOTHERAPY OF HYPERTENSION BASED ON THE RESULTS OF THE MAPEC STUDY

(2010) Francesco Portaluppi et al.   CHRONOBIOLOGY INTERNATIONAL

CHRONOTHERAPY WITH VALSARTAN/AMLODIPINE FIXED COMBINATION: IMPROVED BLOOD PRESSURE CONTROL OF ESSENTIAL HYPERTENSION WITH BEDTIME DOSING

(2010) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

ADMINISTRATION-TIME-DEPENDENT EFFECTS OF SPIRAPRIL ON AMBULATORY BLOOD PRESSURE IN UNCOMPLICATED ESSENTIAL HYPERTENSION

(2010) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

INFLUENCE OF CIRCADIAN TIME OF HYPERTENSION TREATMENT ON CARDIOVASCULAR RISK: RESULTS OF THE MAPEC STUDY

(2010) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

The Bedtime Administration Ameliorates Blood Pressure Variability and Reduces Urinary Albumin Excretion in Amlodipine-Olmesartan Combination Therapy

(2010) Atsushi Hoshino et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Evaluation of Dosing Time-Related Anti-Hypertensive Efficacy of Valsartan in Patients with Type 2 Diabetes

(2010) Katsunori Suzuki et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Effect of dosing time of angiotensin II receptor blockade titrated by self-measured blood pressure recordings on cardiorenal protection in hypertensives: the Japan Morning Surge-Target Organ Protection (J-TOP) study

(2010) Kazuomi Kario et al.   JOURNAL OF HYPERTENSION

Effects of Time of Antihypertensive Treatment on Ambulatory Blood Pressure and Clinical Characteristics of Subjects With Resistant Hypertension

(2009) R. C. Hermida et al.   AMERICAN JOURNAL OF HYPERTENSION

Administration‐Time‐Dependent Effects of Olmesartan on the Ambulatory Blood Pressure of Essential Hypertension Patients

(2009) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

THE CROSSTALK BETWEEN PHYSIOLOGY AND CIRCADIAN CLOCK PROTEINS

(2009) David Duguay et al.   CHRONOBIOLOGY INTERNATIONAL

Bedtime administration of long-acting antihypertensive drugs restores normal nocturnal blood pressure fall in nondippers with essential hypertension

(2009) Atsushi Takeda et al.   Clinical and Experimental Nephrology

Chronotherapy With the Angiotensin-Converting Enzyme Inhibitor Ramipril in Essential Hypertension

(2009) Ramón C. Hermida et al.   HYPERTENSION

24-Hour and Nighttime Blood Pressures in Type 2 Diabetic Hypertensive Patients Following Morning or Evening Administration of Olmesartan

(2009) Santiago Tofé Povedano et al.   Journal of Clinical Hypertension

Bottom blood pressure or bottom cardiovascular risk? How far can cardiovascular risk be reduced?

(2009) Alberto Zanchetti   JOURNAL OF HYPERTENSION

Chronotherapy With Nifedipine GITS in Hypertensive Patients: Improved Efficacy and Safety With Bedtime Dosing

(2008) R. C. Hermida et al.   AMERICAN JOURNAL OF HYPERTENSION

Ambulatory Blood Pressure Is a Better Marker Than Clinic Blood Pressure in Predicting Cardiovascular Events in Patients With/Without Type 2 Diabetes

(2008) K. Eguchi et al.   AMERICAN JOURNAL OF HYPERTENSION

Prognostic Influence of Office and Ambulatory Blood Pressures in Resistant Hypertension

(2008) Gil F. Salles et al.   ARCHIVES OF INTERNAL MEDICINE

Comparison of the Effects on Ambulatory Blood Pressure of Awakening versus Bedtime Administration of Torasemide in Essential Hypertension

(2008) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Resistant Hypertension: Diagnosis, Evaluation, and Treatment

(2008) David A. Calhoun et al.   HYPERTENSION

Disparate Estimates of Hypertension Control From Ambulatory and Clinic Blood Pressure Measurements in Hypertensive Kidney Disease

(2008) Velvie Pogue et al.   HYPERTENSION

Chronotherapy Improves Blood Pressure Control and Reverts the Nondipper Pattern in Patients With Resistant Hypertension

(2007) Ramón C. Hermida et al.   HYPERTENSION

Daytime and Nighttime Blood Pressure as Predictors of Death and Cause-Specific Cardiovascular Events in Hypertension

(2007) Robert H. Fagard et al.   HYPERTENSION