Article
Peripheral Vascular Disease
Eline H. Groenland, Jean-Paul A. C. Vendeville, Remy H. H. Bemelmans, Houshang Monajemi, Michiel L. Bots, Frank L. J. Visseren, Wilko Spiering
Summary: This study evaluated the agreement between app-assisted home blood pressure monitoring and 24-hour ambulatory blood pressure monitoring, and found significant disagreement between the two methods. App-assisted home blood pressure monitoring had high sensitivity in diagnosing sustained and masked hypertension, and can be used as a complement to 24-hour ambulatory blood pressure monitoring.
Article
Peripheral Vascular Disease
Kenji Matsumoto, Zhezhen Jin, Shunichi Homma, Mitchell S. V. Elkind, Joseph E. Schwartz, Tatjana Rundek, Carlo Mannina, Kazato Ito, Ralph L. Sacco, Marco R. Di Tullio
Summary: Sophisticated blood pressure measurements such as ambulatory blood pressure were found to be better independent predictors of incident atrial fibrillation compared to central blood pressure in an older population-based cohort. Office blood pressure, on the other hand, was inadequate for predicting atrial fibrillation in this study.
JOURNAL OF HYPERTENSION
(2021)
Article
Behavioral Sciences
Liwei Shen, Xiaoli Yang, Wenmei Lu, Weijie Chen, Xiaofei Ye, Danhong Wu
Summary: Abnormal blood pressure regulation is a common feature of autonomic dysfunction in Parkinson's disease patients. This study found significant differences in circadian blood pressure rhythm between different disease stages and subtypes of PD patients, with reverse dipping being more common in advanced PD patients. 24-hour ambulatory blood pressure monitoring is crucial for evaluating blood pressure alterations in PD patients and clinicians should be vigilant about reverse dipping to prevent serious clinical events.
BRAIN AND BEHAVIOR
(2022)
Article
Peripheral Vascular Disease
Kenji Matsumoto, Zhezhen Jin, Shunichi Homma, Mitchell S. V. Elkind, Joseph E. Schwartz, Tatjana Rundek, Carlo Mannina, Kazato Ito, Ralph L. Sacco, Marco R. Di Tullio
Summary: In this study, office systolic blood pressure showed weak association with stroke, central blood pressure was not significantly associated with stroke, but all ambulatory blood pressure variables (systolic and diastolic) were significantly linked to stroke. Additionally, ambulatory diastolic blood pressure was found to be a stronger predictor of stroke compared to ambulatory systolic blood pressure.
Review
Peripheral Vascular Disease
Justine Huart, Alexandre Persu, Jean-Philippe Lengele, Jean-Marie Krzesinski, Francois Jouret, George S. Stergiou
Summary: The nondipping blood pressure pattern refers to an inadequate decrease in BP levels during nighttime sleep, disrupting the circadian BP rhythm as observed in 24-hour ambulatory BP monitoring. Patients with this pattern experience poorer renal and cardiovascular outcomes regardless of their average 24-hour BP levels. The pathophysiology of nondipping BP involves disruptions in circadian rhythm, autonomic nervous system, and water and sodium regulation, and recent research has also suggested a potential role of gut microbiota in this pattern.
Article
Medicine, General & Internal
Francesca Coccina, Anna M. Pierdomenico, Chiara Cuccurullo, Jacopo Pizzicannella, Oriana Trubiani, Sante D. Pierdomenico
Summary: The study aimed to assess the risk of heart failure in elderly treated hypertensive patients with different types of hypertension. The results showed that patients with uncontrolled hypertension, nonresistant hypertension, and resistant hypertension had a significantly higher risk of developing heart failure compared to those with controlled hypertension.
Article
Clinical Neurology
Lucia Pinilla, Ivan D. Benitez, Esther Gracia-Lavedan, Gerard Torres, Olga Minguez, Maria Aguila, Adriano Targa, Mireia Dalmases, Olga Mediano, Juan F. Masa, Maria J. Masdeu, Ferran Barbe, Manuel Sanchez-de-la-Torre
Summary: This study aimed to identify the main contributors to explain the nondipper profile in obstructive sleep apnea (OSA) by characterizing the polysomnography (PSG) parameters associated with alterations in the circadian blood pressure (BP) pattern.
Article
Clinical Neurology
Shawn Jing-Sheng Seah, Shi Ting Chiu, As Tar Thant, Siew Pang Chan, Yi-Hui Ou, Yao Hao Teo, Serene Wong, Chieh-Yang Koo, Ferran Barbe, Chi-Hang Lee
Summary: Traditionally, respiratory sleep indices have been reported based on average total sleep time. This study investigates the relationship between the hour-to-hour variability of these indices and blood pressure. The results show that the hour-to-hour variability of AHI and ODI is independently associated with 24-hour pulse pressure, indicating the potential clinical relevance of this new-found association.
Article
Endocrinology & Metabolism
Javiera Cortes-Rios, Maria Rodriguez-Fernandez
Summary: The timing of antihypertensive medications affects the long-term cardiovascular risk of hypertensive individuals. However, the underlying causes and mechanisms of this timing-dependent antihypertensive effect are not yet understood.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Peripheral Vascular Disease
John W. McEvoy, Wen-Yi Yang, Lutgarde Thijs, Zhen-Yu Zhang, Jesus D. Melgarejo, Jose Boggia, Tine W. Hansen, Kei Asayama, Takayoshi Ohkubo, Eamon Dolan, Katarzyna Stolarz-Skrzypek, Sofia Malyutina, Edoardo Casiglia, Lars Lind, Jan Filipovsky, Gladys E. Maestre, Yan Li, Ji-Guang Wang, Yutaka Imai, Kalina Kawecka-Jaszcz, Edgardo Sandoya, Krzysztof Narkiewicz, Eoin O'Brien, Thomas Vanassche, Jan A. Staessen
Summary: Using ambulatory blood pressure monitor data, the study suggests that isolated diastolic hypertension defined by 2017 ACC/AHA criteria is not a risk factor for cardiovascular disease in adults aged 50 years or older but is a risk factor among younger adults. Age is an important consideration in the clinical management of adults with isolated diastolic hypertension.
Review
Biochemistry & Molecular Biology
Jiayang Zhang, Ruoyu Sun, Tingting Jiang, Guangrui Yang, Lihong Chen
Summary: Blood pressure follows a circadian rhythm, with disruptions potentially leading to worsened cardiovascular and renal outcomes. This review summarizes current understanding of the circadian blood pressure regulation and provides a therapeutic overview of its relationship to cardiovascular and renal health and disease.
Article
Medicine, Research & Experimental
Li-qin Duan, Qiong Li, Li Zhao, Jin-fang Zhao, Min Guo, Hong-tao Shi, Lin Zhang, Qing-hua Han
Summary: This study found that the baseline salt intake of hypertensive patients in Shanxi Province was high, and there was a positive correlation between urinary sodium excretion and blood pressure. Controlling urinary sodium concentration may help regulate blood pressure rhythm.
ADVANCES IN THERAPY
(2021)
Article
Pharmacology & Pharmacy
Ali Coner, Ertan Akbay, Sinan Akinci, Gokhan Ozyildiz, Gultekin Genctoy, Haldun Muderrisoglu
Summary: The study found a high rate of reverse dipping blood pressure pattern in the normotensive population, with albumin-to-creatinine ratio and hs-CRP levels being associated with its presence.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2021)
Article
Health Care Sciences & Services
Domenico Di Raimondo, Gaia Musiari, Alessandra Casuccio, Daniela Colomba, Giuliana Rizzo, Edoardo Pirera, Antonio Pinto, Antonino Tuttolomondo
Summary: Several studies indicate that the degree of nocturnal blood pressure reduction is related to organ damage and prognosis in hypertensive patients, with extreme dippers potentially having the lowest 24-hour pressure load and less cardiac remodeling.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Wei Gao, Yanwen Jin, Ting Bao, Yan Huang
Summary: Current studies have shown a high incidence of masked hypertension in Asian countries, but the use of ambulatory blood pressure monitoring (ABPM) is limited. This study compared ABPM and office blood pressure (OBP) in primary care for a high-risk population of hypertension. The results showed that ABPM had a significantly higher positive rate in diagnosing hypertension compared to OBP. ABPM can effectively screen for masked hypertension and nocturnal hypertension in primary care, making it necessary for high-risk populations.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Ramon C. Hermida, Juan J. Crespo, Manuel Dominguez-Sardina, Alfonso Otero, Ana Moya, Maria T. Rios, Elvira Sineiro, Maria C. Castineira, Pedro A. Callejas, Lorenzo Pousa, Jose L. Salgado, Carmen Duran, Juan J. Sanchez, Jose R. Fernandez, Artemio Mojon, Diana E. Ayala
EUROPEAN HEART JOURNAL
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Ramon C. Hermida, Artemio Mojon, Jose R. Fernandez
EUROPEAN HEART JOURNAL
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Ramon C. Hermida, Jose R. Fernandez, Artemio Mojon
EUROPEAN HEART JOURNAL
(2020)
Article
Biology
Ramon C. Hermida, Jose R. Fernandez, Artemio Mojon
CHRONOBIOLOGY INTERNATIONAL
(2020)
Article
Biology
Ramon C. Hermida, Artemio Mojon, Jose R. Fernandez
CHRONOBIOLOGY INTERNATIONAL
(2020)
Review
Cardiac & Cardiovascular Systems
Ramon C. Hermida, Ramon G. Hermida-Ayala, Michael H. Smolensky, Artemio Mojon, Juan J. Crespo, Alfonso Otero, Maria T. Rios, Manuel Dominguez-Sardina, Jose R. Fernandez
CURRENT CARDIOLOGY REPORTS
(2020)
Article
Biology
Ramon C. Hermida, Artemio Mojon, Jose R. Fernandez
CHRONOBIOLOGY INTERNATIONAL
(2020)
Review
Biochemistry & Molecular Biology
Ramon C. Hermida, Ramon G. Hermida-Ayala, Michael H. Smolensky, Artemio Mojon, Jose R. Fernandez
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
(2020)
Article
Biology
Ramon C. Hermida, Michael H. Smolensky, Horia Balan, Richard J. Castriotta, Juan J. Crespo, Yaron Dagan, Sherine El-Toukhy, Jose R. Fernandez, Garret A. FitzGerald, Akio Fujimura, Yong-Jian Geng, Ramon G. Hermida-Ayala, Antonio P. Machado, Luiz Menna-Barreto, Artemio Mojon, Alfonso Otero, R. Daniel Rudic, Eva Schernhammer, Carsten Skarke, Tomoko Y. Steen, Martin E. Young, Xiaoyun Zhao
Summary: Current hypertension guidelines lack recommendations on treatment timing, overlooking the impact of circadian rhythms on medication effects. Studies on ingestion-time trials for hypertension should adhere to strict guidelines including recruitment of participants based on ABPM diagnosis, selecting treatment times based on internal biological time, and using ABPM as the primary method for blood pressure assessment.
CHRONOBIOLOGY INTERNATIONAL
(2021)
Article
Nutrition & Dietetics
Ana Lago-Sampedro, Ailec Ho-Plagaro, Sara Garcia-Serrano, Concepcion Santiago-Fernandez, Cristina Rodriguez-Diaz, Carlos Lopez-Gomez, Flores Martin-Reyes, Gonzalo Ruiz-Aldea, Guillermo Alcain-Martinez, Montserrat Gonzalo, Custodia Montiel-Casado, Jose R. Fernandez, Eduardo Garcia-Fuentes, Francisca Rodriguez-Pacheco
Summary: The study revealed that oleic acid plays a role in restoring the circadian rhythm of clock genes in intestinal tissues of obese patients, influencing their behavior.
CLINICAL NUTRITION
(2021)
Review
Clinical Neurology
Ramon C. Hermida, Artemio Mojon, Ramon G. Hermida-Ayala, Michael H. Smolensky, Jose R. Fernandez
Summary: The evidence suggests that elevated asleep blood pressure and blunted sleep-time relative blood pressure decline are significant independent prognostic markers of cardiovascular disease risk. Treating hypertension at bedtime/evening instead of upon-waking/morning schedule produces better clinical benefits. Current guidelines do not adequately address this issue.
SLEEP MEDICINE REVIEWS
(2021)
Review
Pharmacology & Pharmacy
Ramon C. Hermida, Ramon G. Hermida-Ayala, Michael H. Smolensky, Artemio Mojon, Jose R. Fernandez
Summary: Current research suggests that taking hypertension medications at bedtime is more beneficial than taking them in the morning, leading to better reduction of asleep blood pressure, decreased cardiovascular disease risk, and improved organ function.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Article
Cardiac & Cardiovascular Systems
Ramon C. Hermida, Diana E. Ayala, Artemio Mojon, Michael H. Smolensky, Juan J. Crespo, Alfonso Otero, Manuel Dominguez-Sardina, Ana Moya, Maria T. Rios, Maria C. Castineira, Pedro A. Callejas, Lorenzo Pousa, Elvira Sineiro, Jose L. Salgado, Carmen Duran, Juan J. Sanchez, Jose R. Fernandez
Summary: The study found that ABPM outperforms traditional OBPM in predicting cardiovascular disease outcomes, and can be used to replace in-clinic SBP measurements for improved accuracy. Using asleep systolic BP mean and sleep-time relative SBP decline as ABPM-derived predictive factors significantly enhanced the calibration, diagnostic accuracy, discrimination, and performance of the CVD risk stratification model.
REVISTA ESPANOLA DE CARDIOLOGIA
(2021)
Review
Clinical Neurology
Michael H. Smolensky, Ami P. Shah, Jose R. Fernandez, Linda Sackett-Lundeen, Ramon C. Hermida
Summary: The aim of this study was to substantiate the 24-hour pattern in the occurrence of childhood febrile seizures (CFSs) and discuss its potential circadian rhythm-dependencies. Eight articles were included in a comprehensive search of the literature, with a total of 2461 CFSs cases from different countries. A 24-hour pattern in the onset of CFSs was validated, with the highest proportion occurring at 18:04 and the lowest at 06:00. The time-of-day risk of CFSs is likely influenced by multiple circadian rhythms, including cytokines and melatonin.
Review
Biology
Ramon C. Hermida, Michael H. Smolensky, Artemio Mojon, Jose R. Fernandez
Summary: The research on molecular and laboratory animal circadian rhythm has greatly increased in the past few decades. However, the lack of formal training and expertise in human circadian rhythm research among investigators conducting translational circadian medicine trials has led to deficient design and questionable findings. This has caused unnecessary controversy and hindered advances in patient care. Overall rating: 7/10
CHRONOBIOLOGY INTERNATIONAL
(2023)