Regulation and Function of TMEM16F in Renal Podocytes

Differential effects of anoctamins on intracellular calcium signals

(2017) Inês Cabrita et al.   FASEB JOURNAL

Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+ and plasma membrane lipid

(2017) Rainer Schreiber et al.   JOURNAL OF PHYSIOLOGY-LONDON

CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6)

(2017) Filipa Simões et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A

(2017) Cristina Paulino et al.   eLife

TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice—Brief ReportHighlights

(2016) Ayesha A. Baig et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ion channels in regulated cell death

(2016) Karl Kunzelmann   CELLULAR AND MOLECULAR LIFE SCIENCES

Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

(2016) Jiraporn Ousingsawat et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

TMEM16F Regulates Baseline Phosphatidylserine Exposure and Cell Viability in Human Embryonic Kidney Cells

(2016) Laura K. Schenk et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Structural basis for phospholipid scrambling in the TMEM16 family

(2016) Janine D Brunner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cl− channels in apoptosis

(2016) Podchanart Wanitchakool et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage

(2016) Nadine J. A. Mattheij et al.   FASEB JOURNAL

Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion

(2016) Yu Hu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphatidylserine exposure is required for ADAM17 sheddase function

(2016) Anselm Sommer et al.   Nature Communications

Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1

(2015) Jiraporn Ousingsawat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cell biology of renal filtration

(2015) Rizaldy P. Scott et al.   JOURNAL OF CELL BIOLOGY

Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing

(2015) Lalida Sirianant et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Modulating Ca2+ signals: a common theme for TMEM16, Ist2, and TMC

(2015) Karl Kunzelmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation

(2015) V Forschbach et al.   Cell Death & Disease

Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages

(2015) Jiraporn Ousingsawat et al.   Nature Communications

The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function

(2014) Diana Faria et al.   KIDNEY INTERNATIONAL

Structure and Function of TMEM16 Proteins (Anoctamins)

(2014) Nicoletta Pedemonte et al.   PHYSIOLOGICAL REVIEWS

The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes

(2014) D O Wennmann et al.   Cell Death & Disease

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

(2013) J. Suzuki et al.   SCIENCE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents

(2013) A Kmit et al.   Cell Death & Disease

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues

(2012) Harald WA Ehlen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Podocytes of AT2 Receptor Knockout Mice Are Protected from Angiotensin II-Mediated RAGE Induction

(2011) Christiane Rüster et al.   AMERICAN JOURNAL OF NEPHROLOGY

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

Anoctamin 6 is an essential component of the outwardly rectifying chloride channel

(2011) J. R. Martins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and Function of Epithelial Anoctamins

(2010) Rainer Schreiber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

(2008) Akio Kobayashi et al.   Cell Stem Cell

Mechanisms of angiotensin II signaling on cytoskeleton of podocytes

(2008) Hsiang-Hao Hsu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM